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Srivastava, S., Yeung, C. C. S., & Riddell, S. R. (2023). Compromised antigen binding and signaling interfere with bispecific CD19 and CD79a ...

A new study urges CARe when considering multispecific CAR-T cell therapy

research.fredhutch.org/en/news/spotlight/2023/08/tst-leung-bloodadv.html

S, Wang L, Zhu WG, Wang W, Liu X, Shu S, Zhao Y. 2023. The Lin28b/Wnt5a axis drives pancreas cancer through crosstalk between cancer associated ...

Two cans and a string: cancer cells can communicate with neighboring cells

research.fredhutch.org/en/news/spotlight/2023/11/crd-shu-natcommun.html

HP, Riddell SR, Turtle CJ, Maloney DG, Gauthier J. 2023. Factors associated with long-term outcomes of CD19 CAR T-cell therapy for relapsed/refractory ...

Effective immunotherapy for relapsed or treatment-resistant leukemia

research.fredhutch.org/en/news/spotlight/2023/11/crd-liang-bloodadv.html

MJ, Schiffer JT, Cohn LB, Deeks SG, Nussenzweig MC. 2023. Impact of misclassified defective proviruses on HIV reservoir measurements. Nat Commun. ...

How we measure success matters when evaluating HIV therapies

research.fredhutch.org/en/news/spotlight/2023/09/vidd-reeves-natcommun.html

Simon, N., Bradley, P., & Matsen, F. A. (2023). Statistical inference reveals the role of length, GC content, and local sequence in V(D)J ...

Learning the rules of the game behind lymphocyte diversity

research.fredhutch.org/en/news/spotlight/2023/09/phs-russell-elife.html

Ryser, M. D., Gard, C. C., & Etzioni, R. (2023). Test sensitivity in a prospective cancer screening program: A critique of a common proxy ...

Digging into the math ‘behind the screens’ of cancer surveillance

research.fredhutch.org/en/news/spotlight/2023/09/phs-lange-smmr.html

Haffner MC, Nelson PS, Priceman SJ, Ishihara J, Lee JK. 2023. Targeting advanced prostate cancer with STEAP1 chimeric antigen receptor T cell and ...

Boost and attack approach for metastatic prostate cancer therapy!

research.fredhutch.org/en/news/spotlight/2023/06/ccg-bhatia-natcommun.html

contributed to this work. Hoppe ER, Udy DB, Bradley RK. 2023. Recursive splicing discovery using lariats in total RNA sequencing. Life Sci Alliance. ...

Circling back to RNA sequencing data to map recursive splice sites

research.fredhutch.org/en/news/spotlight/2023/06/ccg-hoppe-lifescialliance.html

Upham SL, Pepper G, Huang ML, Aubert M, Jerome KR. 2023. Liver-Humanized NSG-PiZ Mice Support the Study of Chronic Hepatitis B Virus Infection and ...

Liver-humanized mice to study hepatis B virus infection

research.fredhutch.org/en/news/spotlight/2023/06/vidd-jerome-micro.html

Grivas, P., Wright, J. L., Lam, H.-M., … Hsieh, A. C. 2023. Transcriptional-translational conflict is a barrier to cellular transformation and cancer ...

A seesaw between transcription and translation restrains bladder carcinogenesis

research.fredhutch.org/en/news/spotlight/2023/06/hb-jana-cancercell.html