Multiple Gene Risk Prediction Performance Simulation

Documentation for package ‘mgrp’ version 1.0

mgrp-package	Multiple Gene Risk Prediction Performance Simulation
aucfn	Utility function to calculate AUC of ROC
calcBaselineLOdds	Calculate Baseline Log-Odds for a genotype comprised of a specified number of genes with different frequencies and disease odds ratios.
calcBaselineLOddsFromSample	Calculate Baseline Log-Odds required for a desired disease prevalence given a sample of genotypes, and a genotype profile specifying the risk allele frequencies and the disease odds ratios (see calcBaselineLOdds).
mgrp	Multiple Gene Risk Prediction Performance Simulation
simMultRiskPerf	Simulate genotypes and risk prediction performance.
simulateGenotypes	Simulate risk prediction genotypes and disease states and calculate performance of the risk markers using various measures.
simulateRiskPerf	Simulate genotypes and risk prediction performance.
summarizeRiskSet	Simulate risk prediction genotypes and disease states and calculate performance of the risk markers using various measures.