Multiple Gene Risk Prediction Performance Simulation


[Package List] [Top]

Documentation for package ‘mgrp’ version 1.0

Help Pages

mgrp-package Multiple Gene Risk Prediction Performance Simulation
aucfn Utility function to calculate AUC of ROC
calcBaselineLOdds Calculate Baseline Log-Odds for a genotype comprised of a specified number of genes with different frequencies and disease odds ratios.
calcBaselineLOddsFromSample Calculate Baseline Log-Odds required for a desired disease prevalence given a sample of genotypes, and a genotype profile specifying the risk allele frequencies and the disease odds ratios (see calcBaselineLOdds).
mgrp Multiple Gene Risk Prediction Performance Simulation
simMultRiskPerf Simulate genotypes and risk prediction performance.
simulateGenotypes Simulate risk prediction genotypes and disease states and calculate performance of the risk markers using various measures.
simulateRiskPerf Simulate genotypes and risk prediction performance.
summarizeRiskSet Simulate risk prediction genotypes and disease states and calculate performance of the risk markers using various measures.