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taken from your body and multiplied in a lab. cellular

Checkpoint Inhibitors

research.fredhutch.org/en/patient-care/treatments/immunotherapy/checkpoint-inhibitors.html

Jones, T. I., Jones, P. L., & Tapscott, S. J. (2023). Human DUX4 and porcine DUXC activate similar early embryonic programs in pig muscle cells: ...

This little piggie went to the clinic: pigs as a model of DUX4-linked muscular dystrophy

research.fredhutch.org/en/news/spotlight/2023/03/this-little-piggie-went-to-the-clinic--pigs-as-a-model-of-dux4-l.html

Inhibition of DNA repair factor TFIIH synergizes with TRAIL therapy to induce cell death in KRAS mutant pancreatic cancer.

Functionalizing the genome to find novel pancreatic cancer treatments

research.fredhutch.org/en/news/spotlight/2023/01/hb-moser-cancerresearch.html

interrupted time-series analysis. J Int AIDS Soc. 2023 Apr;26(4):e26083. doi: 10.1002/jia2.26083. PMID: 37051619; PMCID: PMC10098286.

Win-win! A youth health training program could improve HIV service delivery in Sub-Saharan Africa

research.fredhutch.org/en/news/spotlight/2023/08/phs-duerr-jias.html

restriction of HSV-1 by the antiviral protein MxB. J Virol. 2023 Oct 5;97(10):e0083023. doi: 10.1128/jvi.00830-23. Epub ahead of print. PMID: ...

When a single amino acid makes all the difference

research.fredhutch.org/en/news/spotlight/2023/11/hb-geballe-journalofvirology.html

M., Koch, M. A., Gottardo, R., & Salama, N. R. (2023). Single-cell Profiling Uncovers a Muc4 -Expressing Metaplastic Gastric Cell Type Sustained ...

A new cell type with links to gastric cancer steps up for its mugshot

research.fredhutch.org/en/news/spotlight/2023/10/ccsg-obrien-crc.html

Drescher C, Cieslik M, Wang P, Birrer MJ, Paulovich AG. 2023. Proteogenomic analysis of chemo-refractory high-grade serous ovarian cancer. Cell. ...

One step closer to personalized oncology for chemo-resistant ovarian cancer

research.fredhutch.org/en/news/spotlight/2023/10/tst-chowdhury-cell.html

Kohler P, Owens T, Bukusi EA, Ngure K, Ortblad KF. 2023. The fidelity of a pharmacy-based oral HIV pre-exposure prophylaxis delivery model in Kenya. J ...

Expanding the delivery of HIV pre-exposure prophylaxis (PrEP) in Kenya

research.fredhutch.org/en/news/spotlight/2023/05/phs-omollo-jacquirimmundefsyn.html

resistance to PD-1 pathway blockade. Clinical Cancer Res. 2023

Macrophages predict response to immunotherapy in Merkel cell carcinoma

research.fredhutch.org/en/news/spotlight/2023/11/cc-cherny-clinicalcancerres.html

Nobel Prize for Physiology or Medicine this year (2023). Pseudouridylation was one of the first RNA modifications discovered and is one of the most ...

To Ψ or not to Ψ: how PUS1 knows where to pseudouridylate mRNAs

research.fredhutch.org/en/news/spotlight/2023/12/bs-grunberg-plosone.html