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Grivas, P., Wright, J. L., Lam, H.-M., … Hsieh, A. C. 2023. Transcriptional-translational conflict is a barrier to cellular transformation and cancer ...

A seesaw between transcription and translation restrains bladder carcinogenesis

research.fredhutch.org/en/news/spotlight/2023/06/hb-jana-cancercell.html

Ferris MT, Hladik F, Schiffer JT, Prlic M, Lund JM. 2023. Memory T cells possess an innate-like function in local protection from mucosal ...

Bystander-activation of CD8 T cells during Herpes Virus 2 infection

research.fredhutch.org/en/news/spotlight/2023/06/vidd-lund-jclininvest.html

Furlong T, Lee SJ, Martin PJ, Storb R, Mielcarek M. 2023. Impact of Donor Statin Treatment on Graft-versus-Host Disease after Allogeneic Hematopoietic ...

Improving blood stem cell transplantation outcomes by treating donors

research.fredhutch.org/en/news/spotlight/2023/10/crd-rashid-transplantcellther.html

recurrent adenomas. Cancer Epidemiol Biomarkers Prev. 2023 Jun 9:EPI-22-1020. doi: 10.1158/1055-9965.EPI-22-1020. Epub ahead of print. PMID: 37294695.

(Bio)marking the spot – utilizing droplet digital PCR for risk biomarker identification in colorectal cancer

research.fredhutch.org/en/news/spotlight/2023/07/tst-grady-cebp.html

KM, Pollack J, Weaver VM, Krummel MF, Headley MB. 2023. Uptake of tumor-derived microparticles induces metabolic reprogramming of macrophages in the ...

Macrophages "eat" tumor-derived microparticles to undergo a metabolic switch

research.fredhutch.org/en/news/spotlight/2023/07/tst-headley-cell.html

Boonyaratanakornkit, J., Rosato, P. C., & Taylor, J. J. (2023). Validation of Ligand Tetramers for the Detection of Antigen-Specific Lymphocytes. ...

Try before you buy: a new method for validating antigen probes used in B and T cell research

research.fredhutch.org/en/news/spotlight/2023/07/vidd-fitzpatrick-jimmuno.html

Azumaya CM, Luyten YA, Chen M, Morgan RD, Stoddard BL. 2023. Structures, activity and mechanism of the Type IIS restriction endonuclease PaqCI. ...

Structural insights of DNA slicing and dicing by PaqCI restriction enzyme

research.fredhutch.org/en/news/spotlight/2023/07/bs-kennedy-nucacidsres.html

Spencer A, Holmberg LA, Furlan SN, Varelias A, Hill GR. 2023. TIGIT inhibition and lenalidomide synergistically promote antimyeloma immune responses ...

Something new and something old synergize to limit multiple myeloma relapse

research.fredhutch.org/en/news/spotlight/2023/04/crd-minnie-jclininvest.html

Dauparas J, Baek M, Abedi MH, Baker D, Bradley P. 2023. Peptide-binding specificity prediction using fine-tuned protein structure prediction networks. ...

Protein code and shape used to predict peptide-protein interactions

research.fredhutch.org/en/news/spotlight/2023/05/phs-motmaen-pnas.html

transcriptional cyclin-dependent kinases. Sci Transl Med. 2023 May 3;15(694):eabn9674. doi: 10.1126/scitranslmed.abn9674.   

Pancreatic ductal adenocarcinoma subtypes: what your type means?

research.fredhutch.org/en/news/spotlight/2023/05/hb-kugel-science0.html