My research interests have been in the developing novel statistical tools for medical decision making in the field of disease screening, diagnosis, prognosis and outcome prediction, including
Evaluation of clinical utilities of novel biomarkers and risk models with censored time-to-event outcome.
Dynamic risk prediction and disease surveillance with longitudinal biomarkers.
Study design of biomarker studies.
Evaluation of cancer screening process (recruitment, screening, diagnosis, and referral for treatment) using electronic medical records from health care systems.
The research has been motivated by and integrated with my collaboration through the Early Detection Research Network (EDRN) and the Population-Based Research Optimizing Screening through Personalized Regimens (PROSPR), with the ultimate goal of improving survival outcomes and reduce burden of the disease in the population.