I want to understand how Adenovirus protein VII disrupts host chromatin and what the outcomes of that disruption are. In part, I am using a model organism approach to determine whether protein VII can destabilize the fundamental unit of chromatin—the nucleosome. When I’m not in lab, you can find me cooking, working out, relishing the era of Peak TV, or, on occasion, hiking.
I am interested in using nuclear-replicating viruses as tools to interrogate the function of host chromatin factors. I am currently characterizing the role of histone variants in herpes simplex virus 1 (HSV-1) infection using biochemical techniques, molecular genetics and fluorescence microscopy. Outside of the lab, I play trumpet and explore Seattle through listening to live music.
I want to understand how Adenovirus protein VII interacts with host cells to modulate immune responses during infections. I am interested in the host proteins targeted by protein VII as the virus circumvents inflammatory signaling and if protein VII could be used as a tool to suppress pathological inflammation observed in other diseases. Outside of lab, I am most often painting miniatures or finding fun activities to do with my daughter
I am studying the role of Adenovirus protein VII and its impact on chromatin reorganization during infection. I am also interested in discovering more about the role of post translational modifications on protein VII and their impact on function and localization. When I am not in the lab I am either out hiking, biking, playing sports, or listening to music.
I am a recent graduate from UW Microbiology, but I was a research intern in the lab prior to starting full time. I am working with yeast, as a model organism, to better understand how Protein VII affects the dynamic chromatin organization in eukaryotic organisms. Outside of lab, I spend my time volunteering at a women's shelter or can be found chasing the next best "hidden gem" restaurant or another sunset with my camera, albeit a rarity in Seattle
I am a recent graduate from Cottey College, majoring in Biology with a certificate in Leadership. I am excited to learn more about the scientific field and grow as a scientist and to learn as much as possible before I make my run in Graduate school. When I am not in the lab, I can be found playing volleyball, hiking, reading another book or exploring new restaurants.
Former lab members
Nick Donadio (2018-2019) - Currently at Seattle Genetics