Publications

2020

Cai EY, Kufeld MN, Schuster S, Arora S, Larkin M, Germanos AA, Hsieh AC, Beronja S. Selective Translation of Cell Fate Regulators Mediates Tolerance to Broad Oncogenic Stress. Cell Stem Cell. 2020 Aug 6;27(2):270-283.e7. doi: 10.1016/j.stem.2020.05.007. Epub 2020 Jun 8. PubMed PMID: 32516567; NIHMSID:NIHMS1598458. 

Ying Z, Beronja S. Embryonic Barcoding of Equipotent Mammary Progenitors Functionally Identifies Breast Cancer Driver. Cell Stem Cell. 2020 Mar 5;26(3):403-419.e4. doi: 10.1016/j.stem.2020.01.009. Epub 2020 Feb 13. PubMed PMID: 32059806; PubMed Central PMCID: PMC7104873.

2019

Pineda, C.M., Gonzalez, D.G., Matte-Martone, C., Boucher, J., Lathrop, E., Gallini, S., Fons, N.R., Xin, T., Tai, K., Marsh, E., Nguyen, D., Suozzi, K.C., Beronja, S. and Greco, V. (2019). Hair follicle regeneration suppresses Ras-driven oncogenic growthJournal of Cell Biology  218: .3212-22.

Liu, Y., Horn, J.L., Banda, K., Goodman, A.Z., Lim, Y., Jana, S., Arora, S., Germanos A.A., Wen, L., Hardin, W.R., Yang, Y.C., Coleman, I.M., Tharakan, R.G., Cai, E.Y., Uo, T., Pillai, S.P.S., Corey, E., Morrissey, C., Chen, Y., Carver, B.S., Plymate, S.R., Beronja, S., Nelson, P.S. and Hsieh, A.C. (2019) The androgen receptor regulates a druggable translational regulon in advanced prostate cancer. Science Translational Medicine 11: 503.

2018 

Ying Z, Sandoval M, Beronja S. Oncogenic activation of PI3K induces progenitor cell differentiation to suppress epidermal growth. Nat Cell Biol. 2018 Nov;20(11):1256-1266. doi: 10.1038/s41556-018-0218-9. Epub 2018 Oct 22. PubMed PMID: 30361695; PubMed Central PMCID: PMC6291208.

2017 

Brown JA, Yonekubo Y, Hanson N, Sastre-Perona A, Basin A, Rytlewski JA, Dolgalev I, Meehan S, Tsirigos A, Beronja S, Schober M. TGF-β-Induced Quiescence Mediates Chemoresistance of Tumor-Propagating Cells in Squamous Cell Carcinoma. Cell Stem Cell. 2017 Nov 2;21(5):650-664.e8. doi: 10.1016/j.stem.2017.10.001. PubMed PMID: 29100014; PubMed Central PMCID: PMC5778452.

Brown S, Pineda CM, Xin T, Boucher J, Suozzi KC, Park S, Matte-Martone C, Gonzalez DG, Rytlewski J, Beronja S, Greco V. Correction of aberrant growth preserves tissue homeostasis. Nature. 2017 Aug 17;548(7667):334-337. doi: 10.1038/nature23304. Epub 2017 Aug 2. PubMed PMID: 28783732; PubMed Central PMCID: PMC5675114. 

2016

Mallarino R, Henegar C, Mirasierra M, Manceau M, Schradin C, Vallejo M, Beronja S, Barsh GS, Hoekstra HE. Developmental mechanisms of stripe patterns in rodents. Nature. 2016 Nov 24;539(7630):518-523. doi: 10.1038/nature20109. Epub 2016 Nov 2. PubMed PMID: 27806375; PubMed Central PMCID: PMC5292240. 

2015

Rytlewski JA, Beronja S. RNAi in the mouse: rapid and affordable gene function studies in a vertebrate system. Wiley Interdiscip Rev Dev Biol. 2015 Jan-Feb;4(1):45-57. doi: 10.1002/wdev.164. Epub 2014 Nov 14. Review. PubMed PMID: 25399926. 

2014

Schramek D, Sendoel A, Segal JP, Beronja S, Heller E, Oristian D, Reva B, Fuchs E. Direct in vivo RNAi screen unveils myosin IIa as a tumor suppressor of squamous cell carcinomas. Science. 2014 Jan 17;343(6168):309-13. doi: 10.1126/science.1248627. PubMed PMID: 24436421; PubMed Central PMCID: PMC4159249. 

2013

Beronja S, Janki P, Heller E, Lien WH, Keyes BE, Oshimori N, Fuchs E. RNAi screens in mice identify physiological regulators of oncogenic growth. Nature. 2013 Sep 12;501(7466):185-90. doi: 10.1038/nature12464. Epub 2013 Aug 14. PubMed PMID: 23945586; PubMed Central PMCID: PMC3774280. 

Beronja S, Fuchs E. RNAi-mediated gene function analysis in skin. Methods Mol Biol. 2013;961:351-61. doi: 10.1007/978-1-62703-227-8_23. PubMed PMID: 23325656; PubMed Central PMCID: PMC4160826.

2012

Chen T, Heller E, Beronja S, Oshimori N, Stokes N, Fuchs E. An RNA interference screen uncovers a new molecule in stem cell self-renewal and long-term regeneration. Nature. 2012 Apr 4;485(7396):104-8. doi: 10.1038/nature10940. PubMed PMID: 22495305; PubMed Central PMCID: PMC3600643. 

2011

Beronja S, Fuchs E. A breath of fresh air in lung regeneration. Cell. 2011 Oct 28;147(3):485-7. doi: 10.1016/j.cell.2011.10.008. PubMed PMID: 22036554; PubMed Central PMCID: PMC3289402. 

Williams SE, Beronja S, Pasolli HA, Fuchs E. Asymmetric cell divisions promote Notch-dependent epidermal differentiation. Nature. 2011 Feb 17;470(7334):353-8. doi: 10.1038/nature09793. PubMed PMID: 21331036; PubMed Central PMCID: PMC3077085.

2010

Beronja S, Livshits G, Williams S, Fuchs E. Rapid functional dissection of genetic networks via tissue-specific transduction and RNAi in mouse embryos. Nat Med. 2010 Jul;16(7):821-7. doi: 10.1038/nm.2167. Epub 2010 Jun 6. PubMed PMID: 20526348; PubMed Central PMCID: PMC2911018. 

2009

Laprise P, Lau KM, Harris KP, Silva-Gagliardi NF, Paul SM, Beronja S, Beitel GJ, McGlade CJ, Tepass U. Yurt, Coracle, Neurexin IV and the Na(+),K(+)-ATPase form a novel group of epithelial polarity proteins. Nature. 2009 Jun 25;459(7250):1141-5. doi: 10.1038/nature08067. PubMed PMID: 19553998. 

2006

Laprise P, Beronja S, Silva-Gagliardi NF, Pellikka M, Jensen AM, McGlade CJ, Tepass U. The FERM protein Yurt is a negative regulatory component of the Crumbs complex that controls epithelial polarity and apical membrane size. Dev Cell. 2006 Sep;11(3):363-74. doi: 10.1016/j.devcel.2006.06.001. PubMed PMID: 16950127; PubMed Central PMCID: PMC2834949. 

2005

Beronja S, Laprise P, Papoulas O, Pellikka M, Sisson J, Tepass U. Essential function of Drosophila Sec6 in apical exocytosis of epithelial photoreceptor cells. J Cell Biol. 2005 May 23;169(4):635-46. doi: 10.1083/jcb.200410081. Epub 2005 May 16. PubMed PMID: 15897260; PubMed Central PMCID: PMC2171699. 

Mehta SQ, Hiesinger PR, Beronja S, Zhai RG, Schulze KL, Verstreken P, Cao Y, Zhou Y, Tepass U, Crair MC, Bellen HJ. Mutations in Drosophila sec15 reveal a function in neuronal targeting for a subset of exocyst components. Neuron. 2005 Apr 21;46(2):219-32. doi: 10.1016/j.neuron.2005.02.029. PubMed PMID: 15848801.