Current Projects
Communicating Health Information and Improving Coordination with Primary Care (CHIIP) Study
Working with colleagues at St. Jude Children’s Research Hospital, this randomized clinical trial (NCT03104543) is evaluating strategies to improve control of high blood pressure, abnormal blood cholesterol, and high blood sugar levels among long-term childhood cancer survivors. This study is being funded by the National Cancer Institute.
Dexrazoxane and Prevention of Anthracycline-Related Cardiomyopathy in Childhood Cancer Survivors
This Children's Oncology Group study (ALTE11C2; NCT01790152) is assessing the efficacy of dexrazoxane in ameliorating anthracycline-related cardiomyopathy among a cohort of children previously treated on dexrazoxane-containing legacy clinical trials. This study is being funded by the Leukemia & Lymphoma Society, St. Baldrick’s Foundation, and the National Cancer Institute.
ECHOS
This study is examining the trajectory of echocardiographic changes among childhood cancer survivors at risk for cancer therapy-related cardiomyopathy. Funded by the Rally Foundation, we are collaborating with colleagues at the Children’s Oncology Group, City of Hope, Emory University, Hospital for Sick Children (Toronto), Seattle Children’s, University of Minnesota, and University of Washington to create a large imaging biorepository of echocardiograms from children and young adults treated for cancer.
Improving Access to Cancer Survivorship via Telehealth (IMPACT) Study
Working with partners through the SCCA Network and the WWAMI region Practice & Research Network (WPRN), this pilot randomized clinical trial (NCT04081779) seeks to determine the feasibility and preliminary efficacy of delivering survivorship care to rural and Latino cancer survivors across the WWAMI region using a lay health educator model. This work is funded by the National Cancer Institute.
Late Effects Among Survivors of Hematopoietic Cell Transplantation (HCT)
We are leveraging data from Washington State’s hospitalization and cancer registries to determine the long-term health effects experienced by survivors of HCT treated at Fred Hutch. Studies have examined a range of outcomes including global hospitalizations, cardiovascular health, kidney health, and late infections.
SALSA: Study of Active LifeStyle Activation
Using an adaptive study design, this trial seeks to determine if various innovative intervention strategies can help childhood cancer survivors improve their physical activity and dietary habits in order to reduce their long-term risk of early cardiovascular disease. Survivors are being recruited in collaboration with St. Jude Children’s Research Hospital and with funding from the National Cancer Institute.
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