Lab Members

Philip Greenberg, MD

Philip Greenberg, MD

Title: Principal Investigator
Phone: 206.667.4462

Investigator Profile
Member & Head, Program of Immunology, Clinical Research Division, Fred Hutch  
Professor of Immunology and Medicine, University of Washington

Shannon Oda, PhD

Shannon Oda, PhD

Title: Research Associate

Shannon is developing novel immunomodulatory fusion proteins (IFPs) as an engineering strategy to enable T cells to overcome inhibitory obstacles in the tumor microenvironment. She is examining how IFP expression impacts T cell programming, including improved metabolism and resistance to exhaustion, and has shown significantly enhanced primary human T cell function and outcomes in hematological and solid tumor models.

Thomas Schmitt, PhD

Thomas Schmitt, PhD

Title: Research Associate

Tom is generating and optimizing expression vectors encoding high affinity WTI-specific TCR genes for use in T cell therapy trials. He is also developing novel methods for the directed evolution of tumor specific TCRs in vitro.

Rachel Perret, PhD

Rachel Perret, PhD

Title: Senior Staff Scientist

Rachel is developing high affinity TCRs for immunotherapy of acute myeloid leukemia and pancreatic, lung, ovarian and other cancers. She has identified several effective TCRs targeting KRAS and cyclin A1, presented by multiple HLA alleles, thus creating an immunotherapy “toolbox” for clinical use.

Kristin Anderson, PhD

Kristin Anderson, PhD

Title: Post-Doctoral Research Fellow

Kristin studies properties of T cell migration and tumor microenvironments that impact the utility of adoptive T cell therapy for solid tumors, with a focus on ovarian cancer. Chemotherapy, immune checkpoint blockade, cell depletion techniques, and abrogation of other negative T cell regulators are being tested as strategies that might enhance adoptive T cell immunotherapy efficacy.

Leah Schmidt, PhD

Leah Schmidt, PhD

Title: Postdoctoral Research Fellow

Leah is using autochthonous mouse models of cancer to test strategies for improving the efficacy of adoptive immunotherapies.

Tijana Martinov, PhD

Tijana Martinov, PhD

Title: Postdoctoral Research Fellow

Tijana is developing T cell strategies to effectively target and destroy cancerous cells in mouse models of multiple myeloma. 

Ashley Thelen, PhD

Ashley Thelen, PhD

Title: Postdoctoral Research Fellow
Division: athelen@fredhutch.org

Ashley is using genome editing and synthetic biology approaches to enhance T cell fitness for targeting solid tumors.

Natalie Duerkopp

Natalie Duerkopp

Title: Project Manager
Breanna Bates

Breanna Bates

Title: Research Technician
Cheryl Black

Cheryl Black

Title: Research Technician
Madison Burnett

Madison Burnett

Title: Research Technician
Jonah Butler

Jonah Butler

Title: Research Technician
Mary Chaffee

Mary Chaffee

Title: Research Technician
Edison Chiu

Edison Chiu

Title: Research Technician
Nicolas Garcia

Nicolas Garcia

Title: Research Technician
Cody Jenkins

Cody Jenkins

Title: Research Technician
Shwetha Mureli

Shwetha Mureli

Title: Research Technician
Magdalia Suarez

Magdalia Suarez

Title: Research Technician
Xiaoxia (Sasha) Tan

Xiaoxia (Sasha) Tan

Title: Research Technician
Oahn Tran

Oahn Tran

Title: Research Technician
Sarah Daman

Sarah Daman

Title: Lab Aide
Susan Ruskin

Susan Ruskin

Title: Lab Aide
Lena Wirth

Lena Wirth

Title: Lab Aide