Jiang, Y., Cao, H., Deng, H., Guan, L., Langthasa, J., Colburg, D. R., Melemenidis, S., Cotton, R. M., Aleman, J., Wang, X. J., Graves, E. E., Kalbasi, A., Pu, K., Rao, J., Le, Q. T. Gold-siRNA supraclusters enhance the anti-tumor immune response of stereotactic ablative radiotherapy at primary and metastatic tumors. Nature Biotechnology. 2025, 43, 1496-1509
Ruan, B., Deng, W., Che, J., Yi, S., Liu, J., Xu, W., Jiang, Y., Zhou, Y., Xie, P., Zhang, H., Zhao, H., Huang, J. Unimolecular near-infrared chemiluminescent reporter for cascaded multiplex imaging of ischemia-reperfusion injury in the liver-kidney axis. Nature Communications. 2025, 16 (1): 7743
Chen, L., Peng, M., Ouyang, Y., Chen, J., Li, H., Wu, M., Qu, R., Zhou, W., Zhang, C., Jiang, Y.#, Xu, S.#, Wu, W., Jiang, X.#, Zhen, X.# Tuning Second Near-Infrared Fluorescence Activation by Regulating the Excited-State Charge Transfer Dynamics Change Ratio. Journal of the American Chemical Society. 2025, 147,17330−17341 (#Co-Corresponding Author)
Xu, W., Yi, S., Liu, J., Jiang, Y., Huang, J. Nitrile-aminothiol bioorthogonal near-infrared fluorogenic probes for ultrasensitive in vivo imaging. Nature Communications. 2025, 16 (1): 8
Zhou, Y., Xu, W., Ruan, B., Zhu, L., Jiang, Y., Cai, H., Huang, J. Molecular Imaging of Renin Activity using Fluorogenic Nanoprobes for Precision Antihypertensive Therapy. Angewandte Chemie International Edition. 2025, 64, e202416002
Guan, L., Viswanathan, V., Jiang, Y., Vijayakumar, S., Cao, H., Zhao, J., Colburg, D. R., Neuhöfer, P., Zhang, Y., Wang, J., Xu, Y., Laseinde, E. E., Hildebrand, R., Rahman, M., Frock, R., Kong, C., Beachy, P. A., Artandi, S., Le, Q. T. Tert-expressing cells contribute to salivary gland homeostasis and tissue regeneration after radiation therapy. Genes & Development. 2024. 38: 569-582
Liu, Y., Diao, S., Ruan, B., Zhou, Y., Yu, M., Dong, G., Xu, W., Ning, L., Zhou, W., Jiang, Y., Xie, C., Fan, Q., Huang, J. Molecular Engineering of Activatable NIR-II Hemicyanine Reporters for Early Diagnosis and Prognostic Assessment of Inflammatory Bowel Disease. ACS nano 2024; 18 (11): 8437-8451
Ruan, B., Yu, M., Zhou, Y., Xu, W., Liu, Y., Liu, B., Zhu, L., Yi, S., Jiang, Y., Huang, J. Size-Transformable Superoxide-Triggered Nanoreporters for Crosstalk-Free Dual Fluorescence/Chemiluminescence Imaging and Urinalysis in Living Mice. Angewandte Chemie International Edition. 2023: e202305812
Li, H., Zhou, S., Wu, M., Qu, R., Wang, X., Chen, W., Jiang, Y., Jiang, X., Zhen, X. Light-driven Self-recruitment of Biomimetic Semiconducting Polymer Nanoparticles for Precise Tumor Vascular Disruption. Advanced Materials. 2023: e2210920
Xu, C., Huang, J., Jiang, Y., He, S., Zhang, C., Pu, K. Nanoparticles with ultrasound-induced afterglow luminescence for tumor-specific theranostics. Nature Biomedical Engineering. 2023; 7 (3): 298-312
Huang, J., Chen, X., Jiang, Y., Zhang, C., He, S., Wang, H., Pu, K. Renal clearable polyfluorophore nanosensors for early diagnosis of cancer and allograft rejection. Nature Materials. 2022; 21 (5): 598-607
Wu, X.*, Jiang, Y.*, Rommelfanger, N. J., Yang, F., Zhou, Q., Yin, R., Liu, J., Cai, S., Ren, W., Shin, A., Ong, K. S., Pu, K., Hong, G. Tether-free photothermal deep-brain stimulation in freely behaving mice via wide-field illumination in the near-infrared-II window. Nature Biomedical Engineering. 2022, 6, 754-770 (*Co-First Author)
Jiang, Y., Pu, K. Molecular Probes for Autofluorescence-Free Optical Imaging. Chemical Reviews. 2021; 121 (21): 13086-13131
Xu, C., Jiang, Y., Huang, J., Huang, J., Pu, K. Second Near-Infrared Light-Activatable Polymeric Nanoantagonist for Photothermal Immunometabolic Cancer Therapy. Advanced Materials. 2021; 33 (36): e2101410
Zhang, C., Zeng, Z., Cui, D., He, S., Jiang, Y., Li, J., Huang, J., Pu, K. Semiconducting polymer nano-PROTACs for activatable photo-immunometabolic cancer therapy. Nature Communications. 2021; 12 (1): 2934
Xu, C.*, Jiang, Y.*, Han, Y., Pu, K., Zhang, R. A Polymer Multicellular Nanoengager for Synergistic NIR-II Photothermal Immunotherapy. Advanced Materials. 2021; 33 (14): e2008061 (*Co-First Author)
Huang, J.*, Jiang, Y.*, Li, J., Huang, J., Pu, K. Molecular Chemiluminescent Probes with a Very Long Near-Infrared Emission Wavelength for in Vivo Imaging. Angewandte Chemie International Edition. 2021; 60 (8): 3999-4003 (*Co-First Author)
Jiang, Y., Huang, J., Xu, C., Pu, K. Activatable polymer nanoagonist for second near-infrared photothermal immunotherapy of cancer. Nature Communications. 2021; 12 (1): 742
Li, J., Yu, X., Jiang, Y., He, S., Zhang, Y., Luo, Y., Pu, K. Second Near-Infrared Photothermal Semiconducting Polymer Nanoadjuvant for Enhanced Cancer Immunotherapy. Advanced Materials. 2021; 33 (4): e2003458
Zeng, Z., Zhang, C., Li, J., Cui, D., Jiang, Y., Pu, K. Activatable Polymer Nanoenzymes for Photodynamic Immunometabolic Cancer Therapy. Advanced Materials. 2021; 33 (4): e2007247
Dang, Q.*, Jiang, Y.*, Wang, J., Wang, J., Zhang, Q., Zhang, M., Luo, S., Xie, Y., Pu, K., Li, Q., Li, Z. Room-Temperature Phosphorescence Resonance Energy Transfer for Construction of Near-Infrared Afterglow Imaging Agents. Advanced Materials. 2020; 32 (52): e2006752 (*Co-First Author)
Huang, J., Huang, J., Cheng, P., Jiang, Y., Pu, K. Near-Infrared Chemiluminescent Reporters for In Vivo Imaging of Reactive Oxygen and Nitrogen Species in Kidneys. Advanced Functional Materials. 2020; 30 (39), 2003628
He, S., Jiang, Y., Li, J., Pu, K. Semiconducting Polycomplex Nanoparticles for Photothermal Ferrotherapy of Cancer. Angewandte Chemie International Edition. 2020; 59 (26): 10633-10638
Jiang, Y., Zhao, X., Huang, J., Li, J., Upputuri, P. K., Sun, H., Han, X., Pramanik, M., Miao, Y., Duan, H., Pu, K., Zhang, R. Transformable hybrid semiconducting polymer nanozyme for second near-infrared photothermal ferrotherapy. Nature Communications. 2020; 11 (1): 1857
Huang, J., Jiang, Y., Li, J., He, S., Huang, J., Pu, K. A Renal-Clearable Macromolecular Reporter for Near-Infrared Fluorescence Imaging of Bladder Cancer. Angewandte Chemie International Edition. 2020; 59 (11): 4415-4420
Lyu, Y., He, S., Li, J., Jiang, Y., Sun, H., Miao, Y., Pu, K. A Photolabile Semiconducting Polymer Nanotransducer for Near-Infrared Regulation of CRISPR/Cas9 Gene Editing. Angewandte Chemie International Edition. 2019; 58 (50): 18197-18201
Huang, J., Lyu, Y., Li, J., Cheng, P., Jiang, Y., Pu, K. A Renal-Clearable Duplex Optical Reporter for Real-Time Imaging of Contrast-Induced Acute Kidney Injury. Angewandte Chemie International Edition. 2019; 58 (49): 17796-17804
Li, J., Cui, D., Jiang, Y., Huang, J., Cheng, P., Pu, K. Near-Infrared Photoactivatable Semiconducting Polymer Nanoblockaders for Metastasis-Inhibited Combination Cancer Therapy. Advanced Materials. 2019; 31 (46): e1905091
Huang, J., Xie, C., Zhang, X., Jiang, Y., Li, J., Fan, Q., Pu, K. Renal-clearable Molecular Semiconductor for Second Near-Infrared Fluorescence Imaging of Kidney Dysfunction. Angewandte Chemie International Edition. 2019; 58 (42): 15120-15127
He, S., Xie, C., Jiang, Y., Pu, K. An Organic Afterglow Protheranostic Nanoassembly. Advanced Materials. 2019; 31 (32): e1902672
Cui, D., Li, P., Zhen, X., Li, J., Jiang, Y., Yu, A., Hu, X., Pu, K. Thermoresponsive Semiconducting Polymer Nanoparticles for Contrast-Enhanced Photoacoustic Imaging. Advanced Functional Materials. 2019; 29 (38), 1903461
Jiang, Y., Li, J., Zeng, Z., Xie, C., Lyu, Y., Pu, K. Organic Photodynamic Nanoinhibitor for Synergistic Cancer Therapy. Angewandte Chemie International Edition. 2019; 58 (24): 8161-8165
Wang, Z., Zhen, X., Upputuri, P. K., Jiang, Y., Lau, J., Pramanik, M., Pu, K., Xing, B. Redox-Activatable and Acid-Enhanced Nanotheranostics for Second Near-Infrared Photoacoustic Tomography and Combined Photothermal Tumor Therapy. ACS nano 2019; 13 (5): 5816-5825
Jiang, Y., Huang, J., Zhen, X., Zeng, Z., Li, J., Xie, C., Miao, Q., Chen, J., Chen, P., Pu, K. A generic approach towards afterglow luminescent nanoparticles for ultrasensitive in vivo imaging. Nature Communications. 2019; 10 (1): 2064
Cui, D., Huang, J., Zhen, X., Li, J., Jiang, Y., Pu, K. A Semiconducting Polymer Nano-prodrug for Hypoxia-Activated Photodynamic Cancer Therapy. Angewandte Chemie International Edition. 2019; 58 (18): 5920-5924
Li, J., Huang, J., Lyu, Y., Huang, J., Jiang, Y., Xie, C., Pu, K. Photoactivatable Organic Semiconducting Pro-nanoenzymes. Journal of the American Chemical Society. 2019; 141 (9): 4073-4079
Jiang, Y., Upputuri, P. K., Xie, C., Zeng, Z., Sharma, A., Zhen, X., Li, J., Huang, J., Pramanik, M., Pu, K. Metabolizable Semiconducting Polymer Nanoparticles for Second Near-Infrared Photoacoustic Imaging. Advanced Materials. 2019; 31 (11): e1808166
Wang, Z., Upputuri, P., Zhen, X., Zhang, R., Jiang, Y., Ai, X., Zhang, Z., Hu, M., Meng, Z., Lu, Y., Zheng, Y., Pu, K., Pramanik, M., Xing, B. pH-sensitive and biodegradable charge-transfer nanocomplex for second near-infrared photoacoustic tumor imaging. Nano Research 2019; 12 (1): 49-55
Li, J., Zhen, X., Lyu, Y., Jiang, Y., Huang, J., Pu, K. Cell Membrane Coated Semiconducting Polymer Nanoparticles for Enhanced Multimodal Cancer Phototheranostics. ACS nano 2018; 12 (8): 8520-8530
Jiang, Y., Pu, K. Multimodal Biophotonics of Semiconducting Polymer Nanoparticles. Accounts of Chemical Research. 2018; 51 (8): 1840-1849
Jiang, Y., Pu, K. Molecular Fluorescence and Photoacoustic Imaging in the Second Near-Infrared Optical Window Using Organic Contrast Agents. Advanced Biosystems. 2018; 2 (5): e1700262
Li, J., Xie, C., Huang, J., Jiang, Y., Miao, Q., Pu, K. Semiconducting Polymer Nanoenzymes with Photothermic Activity for Enhanced Cancer Therapy. Angewandte Chemie International Edition. 2018; 57 (15): 3995-3998
Jiang, Y., Li, J., Zhen, X., Xie, C., Pu, K. Dual-Peak Absorbing Semiconducting Copolymer Nanoparticles for First and Second Near-Infrared Window Photothermal Therapy: A Comparative Study. Advanced Materials. 2018; 30 (14): e1705980
Zhou, J.*, Jiang, Y.*, Hou, S., Upputuri, P. K., Wu, D., Li, J., Wang, P., Zhen, X., Pramanik, M., Pu, K., Duan, H. Compact Plasmonic Blackbody for Cancer Theranosis in the Near-Infrared II Window. ACS nano 2018; 12 (3): 2643-2651 (*Co-First Author)
Lyu, Y., Zeng, J., Jiang, Y., Zhen, X., Wang, T., Qiu, S., Lou, X., Gao, M., Pu, K. Enhancing Both Biodegradability and Efficacy of Semiconducting Polymer Nanoparticles for Photoacoustic Imaging and Photothermal Therapy. ACS nano 2018; 12 (2): 1801-1810
Zhen, X., Xie, C., Jiang, Y., Ai, X., Xing, B., Pu, K. Semiconducting Photothermal Nanoagonist for Remote-Controlled Specific Cancer Therapy. Nano Letters 2018; 18 (2): 1498-1505
Jiang, Y., Cui, D., Fang, Y., Zhen, X., Upputuri, P. K., Pramanik, M., Ding, D., Pu, K. Amphiphilic semiconducting polymer as multifunctional nanocarrier for fluorescence/photoacoustic imaging guided chemo-photothermal therapy. Biomaterials. 2017; 145: 168-177
Jiang, Y., Upputuri, P. K., Xie, C., Lyu, Y., Zhang, L., Xiong, Q., Pramanik, M., Pu, K. Broadband Absorbing Semiconducting Polymer Nanoparticles for Photoacoustic Imaging in Second Near-Infrared Window. Nano Letters 2017; 17 (8): 4964-4969
Jiang, Y., Pu, K. Advanced Photoacoustic Imaging Applications of Near-Infrared Absorbing Organic Nanoparticles. Small 2017; 13 (30), 1700710