Paddison Lab

Paddison Lab

Fred Hutch campus

Our Research

The Paddison Lab uses functional genomics to ask biological questions in mammalian stem and progenitor cells. Our primary goal is to define the biological units of self-renewal, expansion, and lineage commitment in model stem cell systems, including: embryonic stem cells, hematopoietic stem cells, neural progenitor cells, and brain tumor initiating cells. We are particularly interested in understanding the molecular mechanisms that allow stem cells to maintain their unique identity and developmental potential.