Prlic Lab

Prlic Lab

Group shot of Prlic lab

Our Research

The Prlic laboratory primarily studies T cell and innate-like T cell responses in mucosal tissues, with a particular interest in understanding how these cells function in different inflammatory environments, including infections and cancer. By defining the functional plasticity and functional potential of T cells in health and a range of different disease states, we aim to understand how we can manipulate these cells to our advantage. Our goal is to understand the molecular basis of cell activation and differentiation to learn how to manipulate the cells for therapeutic purposes and ultimately improve human health.

Research Interests and Current projects

  • Studying and manipulating CD8 T cells and NK cells for therapeutic purposes
  • Mechanisms driving differentiation of naive T cells into memory T cells
  • Bystander activation of memory CD8 T cells
  • MAIT cell responses in mucosal barrier sites