Silberstein Lab

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Clusters of newly-generated mouse hematopoietic cells filling up bone marrow cavity after transplantation

Clusters of newly-generated mouse hematopoietic cells (shown in blue) filling up bone marrow cavity after transplantation

Image courtesy of Marion Mesnieres and Elena Nefyodova, in collaboration with Maes lab, KU Leuven

Our Research

The Silberstein Lab, part of the Stem Cell and Gene Therapy Program at Fred Hutch, investigates the regulation of hematopoietic stem cell self-renewal by extrinsic factors. We aim to develop therapeutic approaches to enhance blood cell production for patients with myelodysplasia, inherited bone marrow failure and those recovering from transplantation.

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News

Silberstein Lab at the Myeloid Meeting 2024

Dr. Silberstein and Sanika Gupte presents findings on the role of Sema4A in myeloid-biased hematopoietic stem cells.

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