Publications
2022
H Nayanga Thirimanne, Feinan Wu, Derek H Janssens, Jherek Swanger, Ahmed Diab, Heather M Feldman, Robert A Amezquita, Raphael Gottardo, Patrick J Paddison, Steven Henikoff, Bruce E Clurman. Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations. eLife. 2022; 11: e74338. Published online 2022 Feb 28. doi: 10.7554/eLife.74338; PMCID: PMC8926403
Markus Welcker, Baiyun Wang, Domniţa-Valeria Rusnac, Yasser Hussaini, Jherek Swanger, Ning Zheng, Bruce E. Clurman. Two diphosphorylated degrons control c-Myc degradation by the Fbw7 tumor suppressor. Sci Adv. 2022 Jan; 8(4): eabl7872. Published online 2022 Jan 28. doi: 10.1126/sciadv.abl7872; PMCID: PMC8797792
2020
Diab A, Gem H, Swanger J, Kim HY, Smith K, Zou G, Raju S, Kao M, Fitzgibbon M, Loeb KR, Rodriguez CP, Méndez E, Galloway DA, Sidorova JM, Clurman BE. FOXM1 drives HPV+ HNSCC sensitivity to WEE1 inhibition. Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):28287-28296. PMID: 33093209.
Chi Y, Carter JH, Swanger J, Mazin AV, Moritz RL, Clurman BE. A novel landscape of nuclear human CDK2 substrates revealed by in situ phosphorylation. Sci Adv. 2020 Apr 17;6(16):eaaz9899. PMID: 32494624; PMCID: PMC7164936.
2019
Loeb KR, Hughes BT, FIssel BM, Osteen NJ, Knoblaugh SE, Grim JE, Drury LJ, Sarver A, Dupuy AJ, Clurman BE. Insertional mutagenesis using the Sleeping Beauty transposon system identifies drivers of erythroleukemia in mice. Sci Rep 2019; 9(1):5488. PubMed PMID: 30940846; PMCID: PMC In Process.
Dye KN, Welcker M, Clurman BE, Roman A, Galloway DA. Merkel cell polyomavirus Tumor antigens expressed in Merkel cell carcinoma function independently of the ubiquitin ligases Fbw7 and β-TrCP. PLoS Pathog 2019; 15(1):e1007543. PubMed PMID: 30689667; PMCID: PMC6366716.
2018
Davis RJ, Gőnen M, Margineantu, DH, Handeli S, Swanger J, Hoellerbauer P, Paddison PJ, Gu H, Raftery D, Grim JE, Hockenbery DM, Margolin AA, Clurman BE. Pan-cancer transcriptional signatures predictive of oncogenic mutations reveal that Fbw7 regulates cancer cell oxidative metabolism. Proc Natl Acad Sci USA 2018; 115(21):5462-5467. PubMed PMID, 29735700; PMCID: PMC6003503.
Goyal N, Rossi MJ, Mazina OM, Chi Y, Moritz, RL, Clurman BE, Mazin AV. RAD54 N-terminal domain is a DNA sensor that couples ATP hydrolysis with branch migration of Holliday junctions. Nat Commun. 2018; 9(1):34. PubMed PMID: 29295984; PMCID: PMC5750232.
2017
Davis RJ, Swanger J, Hughes BT, and Clurman BE. The PP2A-B56 Phosphatase Opposes Cyclin E Autocatalytic Degradation via Site-Specific Dephosphorylation. Molecular and Cellular Biology. 2017; 37(8): e00657-16. PubMed PMID: 28137908; PMCID: PMC5376636.
Calses PC, Dhillon KK, Tucker N, Chi Y, Huang JW, Kawasumi M, Wang Y, Clurman BE, Jacquemont C, Gafken PR, Sugasawa K, Saijo M, and Taniquchi T. DGCR8 Mediates Repair of UV-Induced DNA Damage Independently of RNA Processing. Cell Reports. 2017; 19(1):162-174. PubMed PMID: 28380355; PMCID: PMC5423785.
Kuppers DA, Schmitt TM, Hwang HC, Samraj L, Clurman BE, Fero ML. The miR-106a~363pcl1 miRNA cluster induces murine T cell lymphoma despite transcriptional activation of the p27Kip1 cell cycle inhibitor. Oncotarget. 2017; 8(31):50680-50691. PubMed PMID: 28881594; PMCID: PMC5584189.
2016
Park E, Lee B, Clurman BC, and Lee K. NUP50 is necessary for the survival of primordial germ cells in mouse embryos. Reproduction. 2016; 151(1):51-8. PubMed PMCID: PMC4684727.
2015
Toledo CM, Ding Y, Hoellerbauer P, Davis RJ, Basom R, Girard EJ, Lee E, Corrin P, Hart T, Boluri H, Davison J, Zhang Q, Hardcastle J, Aronow BJ, Plaisier CL, Baliga NS, Moffat J, Lin Q, Li XN, Nam DH, Lee J, Pollard SM, Zhu J, Delrow JJ, Clurman BE, Olson JM, Paddison PJ. Genome-wide CRISPR-Cas9 screens reveal loss of redundancybetween PKMYT1 and WEE1 in Glioblastoma multiforme stem-like cells. Cell Reports. 2015; 13(11):2425-39. PubMed PMID: 26673326; PMCID: PMC4691575.
2014
Zhao H, Faltermeier CM, Mendelsohn L, Porter PL, Clurman BE, Roberts JM. Mislocalization of p27 to the cytoplasm of breast cancer cells confers resistance to anti-HER2 targeted therapy. Oncotarget. 2014; 5(24):12704-14. PubMed PMID: 25587029; PMCID: PMC4350358.
Davis RJ, Welcker M, Clurman BE. Tumor suppression by the Fbw7 ubiquitin ligase: mechanisms and opportunities. Cancer cell. 2014; 26(4):455-64. PubMed PMID: 25314076; PMCID: PMC4227608.
Welcker M, Clurman BE. Oncoprotein ubiquitylation: dimers, degrons, and degradation. Cell cycle (Georgetown, Tex.). 2014; 13(12):1829-30. PubMed PMID: 24866825; PMCID: PMC4111742.
2013
Welcker M, Larimore EA, Swanger J, Bengoechea-Alonso MT, Grim JE, Ericsson J, Zheng N, Clurman BE. Fbw7 dimerization determines the specificity and robustness of substrate degradation. Genes & development. 2013; 27(23):2531-6. PubMed PMID: 24298052; PMCID: PMC3861666.
Hughes BT, Sidorova J, Swanger J, Monnat RJ Jr, Clurman BE. Essential role for Cdk2 inhibitory phosphorylation during replication stress revealed by a human Cdk2 knockin mutation. Proceedings of the National Academy of Sciences of the United States of America. 2013; 110(22):8954-9. PubMed PMID: 23671119; PMCID: PMC3670391.
Zhang B, Gaiteri C, Bodea LG, Wang Z, McElwee J, Podtelezhnikov AA, Zhang C, Xie T, Tran L, Dobrin R, Fluder E, Clurman B, Melquist S, Narayanan M, Suver C, Shah H, Mahajan M, Gillis T, Mysore J, MacDonald ME, Lamb JR, Bennett DA, Molony C, Stone DJ, Gudnason V, Myers AJ, Schadt EE, Neumann H, Zhu J, Emilsson V. Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease. Cell. 2013; 153(3):707-20. PubMed PMID: 23622250; PMCID: PMC3677161.
Pierce NW, Lee JE, Liu X, Sweredoski MJ, Graham RL, Larimore EA, Rome M, Zheng N, Clurman BE, Hess S, Shan SO, Deshaies RJ. Cand1 promotes assembly of new SCF complexes through dynamic exchange of F box proteins. Cell. 2013; 153(1):206-15. PubMed PMID: 23453757; PMCID: PMC3656483.
Hizli AA, Chi Y, Swanger J, Carter JH, Liao Y, Welcker M, Ryazanov AG, Clurman BE. Phosphorylation of eukaryotic elongation factor 2 (eEF2) by cyclin A-cyclin-dependent kinase 2 regulates its inhibition by eEF2 kinase. Molecular and cellular biology. 2013; 33(3):596-604. PubMed PMID: 23184662; PMCID: PMC3554216.
Davis MA, Larimore EA, Fissel BM, Swanger J, Taatjes DJ, Clurman BE. The SCF-Fbw7 ubiquitin ligase degrades MED13 and MED13L and regulates CDK8 module association with Mediator. Genes & development. 2013; 27(2):151-6. PubMed PMID: 23322298; PMCID: PMC3566307.
Sancho R, Blake SM, Tendeng C, Clurman BE, Lewis J, Behrens A. Fbw7 repression by hes5 creates a feedback loop that modulates Notch-mediated intestinal and neural stem cell fate decisions. PLoS biology. 2013; 11(6):e1001586. PubMed PMID: 23776410; PMCID: PMC3679002.
2012
Grim JE, Knoblaugh SE, Guthrie KA, Hagar A, Swanger J, Hespelt J, Delrow JJ, Small T, Grady WM, Nakayama KI, Clurman BE. Fbw7 and p53 cooperatively suppress advanced and chromosomally unstable intestinal cancer. Molecular and cellular biology. 2012; 32(11):2160-7. PubMed PMID: 22473991; PMCID: PMC3372235.
2011
Sengupta T, Abraham G, Xu Y, Clurman BE, Minella AC. Hypoxia-inducible factor 1 is activated by dysregulated cyclin E during mammary epithelial morphogenesis. Molecular and cellular biology. 2011; 31(18):3885-95. PubMed PMID: 21746877; PMCID: PMC3165725.
Kuppers DA, Hwang HC, Jackson AL, Linsley PS, Clurman BE, Fero ML. Effect of Xpcl1 activation and p27(Kip1) loss on gene expression in murine lymphoma. PloS one. 2011; 6(3):e14758. PubMed PMID: 21412408; PMCID: PMC3055866.
Welcker M, Larimore EA, Frappier L, Clurman BE. Nucleolar targeting of the fbw7 ubiquitin ligase by a pseudosubstrate and glycogen synthase kinase 3. Molecular and cellular biology. 2011; 31(6):1214-24. PubMed PMID: 21220517; PMCID: PMC3067902.
2010
Chi Y, Clurman BE. Mass spectrometry-based identification of protein kinase substrates utilizing engineered kinases and thiophosphate labeling. Current protocols in chemical biology. 2010; 2(4):219-34. PubMed PMID: 23839977.
2008
Chi Y, Welcker M, Hizli AA, Posakony JJ, Aebersold R, Clurman BE. Identification of CDK2 substrates in human cell lysates. Genome biology. 2008; 9(10):R149. PubMed PMID: 18847512; PMCID: PMC2760876.
Liu H, Huang J, Wang J, Jiang S, Bailey AS, Goldman DC, Welcker M, Bedell V, Slovak ML, Clurman B, Thayer M, Fleming WH, Epner E. Transvection mediated by the translocated cyclin D1 locus in mantle cell lymphoma. The Journal of experimental medicine. 2008; 205(8):1843-58. PubMed PMID: 18625744; PMCID: PMC2525596.
Grim JE, Gustafson MP, Hirata RK, Hagar AC, Swanger J, Welcker M, Hwang HC, Ericsson J, Russell DW, Clurman BE. Isoform- and cell cycle-dependent substrate degradation by the Fbw7 ubiquitin ligase. The Journal of cell biology. 2008; 181(6):913-20. PubMed PMID: 18559665; PMCID: PMC2426948.
Minella AC, Loeb KR, Knecht A, Welcker M, Varnum-Finney BJ, Bernstein ID, Roberts JM, Clurman BE. Cyclin E phosphorylation regulates cell proliferation in hematopoietic and epithelial lineages in vivo. Genes & development. 2008; 22(12):1677-89. PubMed PMID: 18559482; PMCID: PMC2428064.
Welcker M, Clurman BE. FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation. Nature reviews. Cancer. 2008; 8(2):83-93. PubMed PMID: 18094723.
2007
Garrett-Engele CM, Tasch MA, Hwang HC, Fero ML, Perlmutter RM, Clurman BE, Roberts JM. A mechanism misregulating p27 in tumors discovered in a functional genomic screen. PLoS genetics. 2007; 3(12):e219. PubMed PMID: 18069898; PMCID: PMC2134944.
Minella AC, Grim JE, Welcker M, Clurman BE. p53 and SCFFbw7 cooperatively restrain cyclin E-associated genome instability. Oncogene. 2007; 26(48):6948-53. PubMed PMID: 17486057.
Chang C, Storer BE, Scott BL, Bryant EM, Shulman HM, Flowers ME, Sandmaier BM, Witherspoon RP, Nash RA, Sanders JE, Bedalov A, Hansen JA, Clurman BE, Storb R, Appelbaum FR, Deeg HJ. Hematopoietic cell transplantation in patients with myelodysplastic syndrome or acute myeloid leukemia arising from myelodysplastic syndrome: similar outcomes in patients with de novo disease and disease following prior therapy or antecedent hematologic disorders. Blood. 2007; 110(4):1379-87. PubMed PMID: 17488876; PMCID: PMC1939908.
O'Neil J, Grim J, Strack P, Rao S, Tibbitts D, Winter C, Hardwick J, Welcker M, Meijerink JP, Pieters R, Draetta G, Sears R, Clurman BE, Look AT. FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors. The Journal of experimental medicine. 2007; 204(8):1813-24. PubMed PMID: 17646409; PMCID: PMC2118656.
Besson A, Hwang HC, Cicero S, Donovan SL, Gurian-West M, Johnson D, Clurman BE, Dyer MA, Roberts JM. Discovery of an oncogenic activity in p27Kip1 that causes stem cell expansion and a multiple tumor phenotype. Genes & development. 2007; 21(14):1731-46. PubMed PMID: 17626791; PMCID: PMC1920168.
Chen X, Barton LF, Chi Y, Clurman BE, Roberts JM. Ubiquitin-independent degradation of cell-cycle inhibitors by the REGgamma proteasome. Molecular cell. 2007; 26(6):843-52. PubMed PMID: 17588519; PMCID: PMC2031223.
Welcker M, Clurman BE. Fbw7/hCDC4 dimerization regulates its substrate interactions. Cell division. 2007; 2:7. PubMed PMID: 17298674; PMCID: PMC1802738.
Geng Y, Lee YM, Welcker M, Swanger J, Zagozdzon A, Winer JD, Roberts JM, Kaldis P, Clurman BE, Sicinski P. Kinase-independent function of cyclin E. Molecular cell. 2007; 25(1):127-39. PubMed PMID: 17218276.
2006
Gustafson MP, Xu C, Grim JE, Clurman BE, Knudsen BS. Regulation of cell proliferation in a stratified culture system of epithelial cells from prostate tissue. Cell and tissue research. 2006; 325(2):263-76. PubMed PMID: 16557385.
Neiman PE, Burnside J, Elsaesser K, Hwang H, Clurman BE, Kimmel R, Delrow J. Analysis of gene expression, copy number and palindrome formation with a Dt40 enriched cDNA microarray. Sub-cellular biochemistry. 2006; 40:245-56. PubMed PMID: 17623909.
2005
Gustafson MP, Welcker M, Hwang HC, Clurman BE. Zcchc8 is a glycogen synthase kinase-3 substrate that interacts with RNA-binding proteins. Biochemical and biophysical research communications. 2005; 338(3):1359-67. PubMed PMID: 16263084.
Welcker M, Clurman B. Cell cycle: how cyclin E got its groove back. Current biology: CB. 2005; 15(19):R810-2. PubMed PMID: 16213815.
Minella AC, Clurman BE. Mechanisms of tumor suppression by the SCF(Fbw7). Cell cycle (Georgetown, Tex.). 2005; 4(10):1356-9. PubMed PMID: 16131838.
Minella AC, Welcker M, Clurman BE. Ras activity regulates cyclin E degradation by the Fbw7 pathway. Proceedings of the National Academy of Sciences of the United States of America. 2005; 102(27):9649-54.PubMed PMID: 15980150; PMCID: PMC1172263.
Loeb KR, Kostner H, Firpo E, Norwood T, D Tsuchiya K, Clurman BE, Roberts JM. A mouse model for cyclin E-dependent genetic instability and tumorigenesis. Cancer cell. 2005; 8(1):35-47. PubMed PMID: 16023597.
Hwang HC, Clurman BE. Cyclin E in normal and neoplastic cell cycles. Oncogene. 2005; 24(17):2776-86. PubMed PMID: 15838514.
Welcker M, Clurman BE. The SV40 large T antigen contains a decoy phosphodegron that mediates its interactions with Fbw7/hCdc4. The Journal of biological chemistry. 2005; 280(9):7654-8. PubMed PMID: 15611062.
2004
Thomas DM, Johnson SA, Sims NA, Trivett MK, Slavin JL, Rubin BP, Waring P, McArthur GA, Walkley CR, Holloway AJ, Diyagama D, Grim JE, Clurman BE, Bowtell DD, Lee JS, Gutierrez GM, Piscopo DM, Carty SA, Hinds PW. Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma. The Journal of cell biology. 2004; 167(5):925-34. PubMed PMID: 15583032; PMCID: PMC2172443.
Chen X, Chi Y, Bloecher A, Aebersold R, Clurman BE, Roberts JM. N-acetylation and ubiquitin-independent proteasomal degradation of p21(Cip1). Molecular cell. 2004; 16(5):839-47. PubMed PMID: 15574338.
Ye X, Nalepa G, Welcker M, Kessler BM, Spooner E, Qin J, Elledge SJ, Clurman BE, Harper JW. Recognition of phosphodegron motifs in human cyclin E by the SCF(Fbw7) ubiquitin ligase. The Journal of biological chemistry. 2004; 279(48):50110-9. PubMed PMID: 15364936.
Welcker M, Orian A, Grim JE, Eisenman RN, Clurman BE. A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size. Current biology : CB. 2004; 14(20):1852-7. PubMed PMID: 15498494.
Noseda M, Chang L, McLean G, Grim JE, Clurman BE, Smith LL, Karsan A. Notch activation induces endothelial cell cycle arrest and participates in contact inhibition: role of p21Cip1 repression. Molecular and cellular biology. 2004; 24(20):8813-22. PubMed PMID: 15456857; PMCID: PMC517869.
Welcker M, Orian A, Jin J, Grim JE, Harper JW, Eisenman RN, Clurman BE. The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation. Proceedings of the National Academy of Sciences of the United States of America. 2004; 101(24):9085-90. PubMed PMID: 15150404; PMCID: PMC428477.
2003
Grim JE, Clurman BE. Cycling without CDK2? Trends in cell biology. 2003; 13(8):396-9. PubMed PMID: 12888290.
Welcker M, Singer J, Loeb KR, Grim J, Bloecher A, Gurien-West M, Clurman BE, Roberts JM. Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation. Molecular cell. 2003; 12(2):381-92. PubMed PMID: 14536078.
Grandori C, Wu KJ, Fernandez P, Ngouenet C, Grim J, Clurman BE, Moser MJ, Oshima J, Russell DW, Swisshelm K, Frank S, Amati B, Dalla-Favera R, Monnat RJ Jr. Werner syndrome protein limits MYC-induced cellular senescence. Genes & development. 2003; 17(13):1569-74. PubMed PMID: 12842909; PMCID: PMC196129.
2002
Minella AC, Swanger J, Bryant E, Welcker M, Hwang H, Clurman BE. p53 and p21 form an inducible barrier that protects cells against cyclin E-cdk2 deregulation. Current biology : CB. 2002; 12(21):1817-27. PubMed PMID: 12419181.
Hwang HC, Martins CP, Bronkhorst Y, Randel E, Berns A, Fero M, Clurman BE. Identification of oncogenes collaborating with p27Kip1 loss by insertional mutagenesis and high-throughput insertion site analysis. Proceedings of the National Academy of Sciences of the United States of America. 2002; 99(17):11293-8. PubMed PMID: 12151601; PMCID: PMC123250.
Lindsay ME, Plafker K, Smith AE, Clurman BE, Macara IG. Npap60/Nup50 is a tri-stable switch that stimulates importin-alpha:beta-mediated nuclear protein import. Cell. 2002; 110(3):349-60. PubMed PMID: 12176322.
Platzbecker U, Gooley T, Anasetti C, Appelbaum FR, Clurman B, Doney K, Chauncey T, Flowers ME, Myerson D, Radich JP, Storb R, Witherspoon RP, Deeg HJ. Curative therapy of advanced essential thrombocythemia or polycythemia vera by hemopoietic stem cell transplantation. Leukemia & lymphoma. 2002; 43(7):1409-14. PubMed PMID: 12389621.
2000
Guan T, Kehlenbach RH, Schirmer EC, Kehlenbach A, Fan F, Clurman BE, Arnheim N, Gerace L. Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein export. Molecular and cellular biology. 2000; 20(15):5619-30. PubMed PMID: 10891499; PMCID: PMC86026.
Smitherman M, Lee K, Swanger J, Kapur R, Clurman BE. Characterization and targeted disruption of murine Nup50, a p27(Kip1)-interacting component of the nuclear pore complex. Molecular and cellular biology. 2000; 20(15):5631-42. PubMed PMID: 10891500; PMCID: PMC86029.
Sheaff RJ, Singer JD, Swanger J, Smitherman M, Roberts JM, Clurman BE. Proteasomal turnover of p21Cip1 does not require p21Cip1 ubiquitination. Molecular cell. 2000; 5(2):403-10. PubMed PMID: 10882081.
1999
Singer JD, Gurian-West M, Clurman B, Roberts JM. Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells. Genes & development. 1999; 13(18):2375-87. PubMed PMID: 10500095; PMCID: PMC317026.
Stirewalt DL, Clurman B, Appelbaum FR, Willman CL, Radich JP. p73 mutations and expression in adult de novo acute myelogenous leukemia. Leukemia. 1999; 13(7):985-90. PubMed PMID: 10400412.
1998
Clurman BE, Porter P. New insights into the tumor suppression function of P27(kip1) Proceedings of the National Academy of Sciences of the United States of America. 1998; 95(26):15158-60. PubMed PMID: 9860936; PMCID: PMC33928.
Clurman BE, Groudine M. The CDKN2A tumor-suppressor locus--a tale of two proteins. The New England journal of medicine. 1998; 338(13):910-2. PubMed PMID: 9516230.
Levkau B, Koyama H, Raines EW, Clurman BE, Herren B, Orth K, Roberts JM, Ross R. Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade. Molecular cell. 1998; 1(4):553-63. PubMed PMID: 9660939.
1997
Clurman B, Groudine M. Tumour-suppressor genes. Killer in search of a motive? Nature. 1997; 389(6647):122-3. PubMed PMID: 9296483.
Sheaff RJ, Groudine M, Gordon M, Roberts JM, Clurman BE. Cyclin E-CDK2 is a regulator of p27Kip1. Genes & development. 1997; 11(11):1464-78. PubMed PMID: 9192873.
Tam W, Ben-Yehuda D, Hayward WS. bic, a novel gene activated by proviral insertions in avian leukosis virus-induced lymphomas, is likely to function through its noncoding RNA. Molecular and cellular biology. 1997; 17(3):1490-502. PubMed PMID: 9032277; PMCID: PMC231875.
Neiman PE, Clurman BE, Lobanenkov VV. Molecular pathogenesis of myc-initiated B-cell lymphomas in the bursa of Fabricius. Current topics in microbiology and immunology. 1997; 224:231-8. PubMed PMID: 9308246.
1996
Clurman BE, Sheaff RJ, Thress K, Groudine M, Roberts JM. Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation. Genes & development. 1996; 10(16):1979-90. PubMed PMID: 8769642.
Clurman BE, Roberts JM, Groudine M. Deregulation of cell cycle control in hematologic malignancies. Current opinion in hematology. 1996; 3(4):315-20. PubMed PMID: 9372094.
1995
Clurman BE, Roberts JM. Cell cycle and cancer. Journal of the National Cancer Institute. 1995; 87(20):1499-501. PubMed PMID: 7563177.
Clurman BE, Hayward WS. Multiple proto-oncogene activations in avian leukosis virus-induced lymphomas: evidence for stage-specific events. Molecular and cellular biology. 1989; 9(6):2657-64. PubMed PMID: 2548084; PMCID: PMC362338.
1989
Clurman BE, Hayward WS. Multiple proto-oncogene activations in avian leukosis virus-induced lymphomas: evidence for stage-specific events. Molecular and cellular biology. 1989; 9(6):2657-64. PubMed PMID: 2548084; PMCID: PMC362338.
Book Chapters
Wiman, K., Clurman B., Shih C., Goodenow M., Simon M., Lestrange R., Hayward W., Hayday A., Tonegawa S. Activation of c-myc in Viral and Nonviral Neoplasia. Genetics, Cell Differentiation, Cancer (ed. P. Marks) 1985. Academic Press, NY
Clurman B., Hayward W. 1988. Insertional Activation of Known Oncogenes. Oncogene Activation (ed.G.Klein).; Marcell-Dekkar, NY, 55-95. 3.
Clurman, B., and J. Roberts. 1996. Cell Cycle Control: An Overview. 1996-2002 . The Metabolic and Molecular Bases of Inherited Disease. ed. C. Scriver, A. Beaudet, W. Sly, and D. Valle, McGraw-Hill, New York and in The Genetic Basis of Human Cancer. 1997. ed. K. Kinzler and B. Vogelstein. McGraw-Hill, N.Y.
Clurman, Bruce. Molecular Biology. Chapter 2, ASCO SEP. 2007 American Society of Clinical Oncology. 19-50.
Clurman, Bruce. Molecular Biology. Chapter 2, ASCO SEP. Ed. 2 2009 American Society of Clinical Oncology
Clurman, Bruce. Molecular Biology. Chapter 2, ASCO SEP. Ed. 3 2013. American Society of Clinical Oncology.
Clurman, Bruce. Molecular Biology. Chapter 2, ASCO SEP. Ed. 3 2016. American Society of Clinical Oncology. In Press
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