Publications
2019
Fredricks DN. The Gut Microbiota and Graft-versus-host Disease. J Clin Invest. 2019 May 1;129(5):1808-1817. doi: 10.1172/JCI125797. Epub 2019 May 1. PMCID: PMC6486325.
Sabo MC, Lehman DA, Wang B, Richardson BA, Srinivasan S, Osborn L, Matemo D, Kinuthia J, Fiedler TL, Munch MM, Drake AL, Fredricks DN, Overbaugh J, John-Stewart G, McClelland RS, Graham SM. Associations between vaginal bacteria implicated in HIV acquisition risk and proinflammatory cytokines and chemokines. Sex Transm Infect. 2019 Jun 13. pii: sextrans-2018-053949. doi: 10.1136/sextrans-2018-053949. [Epub ahead of print] PMID: 31197065.
Wright T, Coruh B, Fredricks DN, Kim N. Immune reconstitution inflammatory syndrome associated with disseminated histoplasmosis and TNF-alpha inhibition. Med Mycol Case Rep. 2018 Dec 22;23:62-64. doi: 10.1016/j.mmcr.2018.12.008. eCollection 2019 Mar. PMCID: PMC6325068.
Sabo MC, Balkus JE, Richardson BA, Srinivasan S, Kimani J, Anzala O, Schwebke J, Feidler TL, Fredricks DN, McClelland RS. Association between vaginal washing and vaginal bacterial concentrations. PLoS One. 2019 Jan 24;14(1):e0210825. doi: 10.1371/journal.pone.0210825. eCollection 2019. PMCID: PMC6345501.
Lokken EM, Manguro GO, Abdallah A, Ngacha C, Shafi J, Kiarie J, Jaoko W, Srinivasan S, Fiedler TL, Munch MM, Fredricks DN, McClelland RS, Balkus JE. Association between vaginal washing and detection of Lactobacillus by culture and quantitative PCR in HIV-seronegative Kenyan women: a cross-sectional analysis. Sex Transm Infect. 2019 Jan 29. pii: sextrans-2018-053769. doi: 10.1136/sextrans-2018-053769. [Epub ahead of print]. PMID: 30696752.
McKinnon LR, Achilles SL, Bradshaw CS, Burgener A, Crucitti T, Fredricks DN, Jaspan HB, Kaul R, Kaushic C, Klatt N, Kwon DS, Marrazzo JM, Masson L, McClelland RS, Ravel J, van de Wijgert JHHM, Vodstrcil LA, Tachedjian G. The evolving facets of bacterial vaginosis: implications for HIV transmission. AIDS Res Hum Retroviruses. 2019 Jan 14. doi: 10.1089/AID.2018.0304. [Epub ahead of print]. PMID: 30638028.
2018
Chambers LC, Morgan JL, Lowens MS, Robinson TS, Romano SS, Leipertz GL, Hughes JP, Golden MR, Khosropour CM, Fredricks DN, Manhart LE. Cross-sectional study of urethral exposures at last sexual episode associated with non-gonococcal urethritis among STD clinic patients. Sex Transm Infect. 2018 Sep 4. pii: sextrans-2018-053634. doi: 10.1136/sextrans-2018-053634. [Epub ahead of print]. PMID: 30181326.
Chambers LC, Srinivasan S, Lukehart SA, Ocbamichael N, Morgan JL, Lowens MS, Fredricks DN, Golden MR, Manhart LE. Primary Syphilis in the Male Urethra - A Case Report. Clin Infect Dis. 2018 Sep 10. doi: 10.1093/cid/ciy771. [Epub ahead of print]. PMID: 30202933.
Taneva E, Sinclair S, Mesquita PMM, Weinrick, B, Cameron SA, Cheshenko, Reagle NK, Frank B, Srinivasan S, Fredricks DN, Keller MJ, Herold BC. Vaginal microbiome modulates topical antiretroviral drug pharmacokinetics. JCI Insight. 2018 Jul 12;3(13). pii: 99545. doi: 10.1172/jci.insight.99545. [Epub ahead of print] PMID: 29997295.
Ogimi C, Krantz EM, Golob JL, Waghmare A, Liu C, Leisenring WM, Woodard CR, Marquis S, Kuypers JM, Jerome KR, Pergam SA, Fredricks DN, Sorror ML, Englund JA, Boeckh M. Antibiotic Exposure Prior to Respiratory Viral Infection Is Associated with Progression to Lower Respiratory Tract Disease in Allogeneic Hematopoietic Cell Transplant Recipients. Biol Blood Marrow Transplant. 2018 May 16. pii: S1083-8791(18)30268-4. doi: 10.1016/j.bbmt.2018.05.016. [Epub ahead of print]. PMID: 29777867.
Lannon SM, Adams Waldorf KM, Fiedler T, Kapur RP, Agnew K, Rajagopal L, Gravett MG, Fredricks DN. Parallel detection of lactobacillus and bacterial vaginosis-associated bacterial DNA in the chorioamnion and vagina of pregnant women at term. J Matern Fetal Neonatal Med. 2018 Mar 12:1-9. doi: 10.1080/14767058.2018.1446208. [Epub ahead of print]. PMCID: PMC6135717.
*McClelland RS, Lingappa JR, Srinivasan S, Kinuthia J, John-Stewart GC, Jaoko W, Richardson BA, Yuhas K, Fiedler TL, Mandaliya KN, Munch MM, Mugo NR, Cohen CR, Baeten JM, Celum C, Overbaugh J, Fredricks DN. Key Vaginal Bacteria Associated with Increased Risk of HIV Acquisition in African Women: A Nested Case-Control Study. Lancet Infect Dis. 2018 May;18(5):554-564. doi: 10.1016/S1473-3099(18)30058-6. Epub 2018 Jan 26. PMID: 29396006.
2017
Sivagnanam S, Sengupta DJ, Hoogestraat D, Jain R, Stednick Z, Fredricks DN, Hendrie P, Whimbey E, Podczervinski ST, Krantz EM, Duchin JS, Pergam SA. Seasonal Clustering of Sinopulmonary Mucormycosis in Patients with Hematologic Malignancies at a Large Comprehensive Cancer Center. Antimicrob Resist Infect Control. 2017 Dec 6;6:123. doi: 10.1186/s13756-017-0282-0. eCollection 2017. PMCID: PMC5718160.
Mitchell CM, Srinivasan S, Plantinga A, Wu MC, Reed SD, Guthrie KA, LaCroix AZ, Fiedler T, Munch M, Liu C, Hoffman NG, Blair IA, Newton K, Freeman EW, Joffe H, Cohen L, Fredricks DN. Associations between improvement in genitourinary symptoms of menopause and changes in the vaginal ecosystem. Menopause. 2017 Dec 4. doi: 10.1097/GME.0000000000001037. [Epub ahead of print]. PMCID: PMC5898977.
Bhattacharyya A, Hanafi LA, Sheih A, Golob JL, Srinivasan S, Boeckh MJ, Pergam SA, Mahmood S, Baker KK, Gooley TA, Milano F, Fredricks DN, Riddell SR, Turtle CJ. Graft-Derived Reconstitution of Mucosal-Associated Invariant T Cells after Allogeneic Hematopoietic Cell Transplantation. Biol Blood Marrow Transplant. 2017 Oct 9. pii: S1083-8791(17)30758-9. doi: 10.1016/j.bbmt.2017.10.003. [Epub ahead of print]. PMCID: PMC5806215.
*Golob JL, Pergam SA, Srinivasan S, Fiedler TL, Liu C, Garcia K, Mielcarek M, Ko D, Aker S, Marquis S, Loeffelholz T, Plantinga A, Wu MC, Celustka K, Morrison A, Woodfield M, Fredricks DN. The Stool Microbiota at Neutrophil Recovery is Predictive for Severe Acute Graft versus Host Disease after Hematopoietic Cell Transplantation. Clin Infect Dis. 2017 Aug 18. doi: 10.1093/cid/cix699. [Epub ahead of print]. PMCID: PMC5850019.
Chin A, Pergam SA, Fredricks DN, Hoofnagle AN, Baker KK, Jain R. Evaluation of Posaconazole Serum Concentrations from Delayed-Release Tablets in Patients at High-Risk for Fungal Infections. Antimicrob Agents Chemother. 2017 Sep 22;61(10). pii: e00569-17. doi: 10.1128/AAC.00569-17. Print 2017 Oct. PMCID: PMC5610489.
Heffron R, McClelland RS, Balkus JE, Celum C, Cohen CR, Mugo N, Bukusi E, Donnell D, Lingappa J, Kiarie J, Fiedler T, Munch M, Fredricks DN, Baeten JM; Partners PrEP Study Team. Efficacy of oral pre-exposure prophylaxis (PrEP) for HIV among women with abnormal vaginal microbiota: a post-hoc analysis of the randomised, placebo-controlled Partners PrEP Study. Lancet HIV. 2017 Oct;4(10):e449-e456. doi: 10.1016/S2352-3018(17)30110-8. Epub 2017 Jul 18. PMID: 28732773.
Golob JL, Margolis E, Hoffman NG, Fredricks DN. Evaluating the accuracy of amplicon-based microbiome computational pipelines on simulated human gut microbial communities. BMC Bioinformatics. 2017 May 30;18(1):283. doi: 10.1186/s12859-017-1690-0. PMCID: PMC5450146.
Mitchell CM, Srinivasan S, Zhan X, Wu MC, Reed SD, Guthrie KA, LaCroix AZ, Fiedler T, Munch M, Liu C, Hoffman NG, Blair IA, Newton K, Freeman EW, Joffe H, Cohen L, Fredricks DN. Vaginal microbiota and genitourinary menopausal symptoms: a cross-sectional analysis. Menopause. 2017 Oct;24(10):1160-1166. doi: 10.1097/GME.0000000000000904. PMCID: PMC5607086.
Korhonen CJ, Srinivasan S, Huang D, Ko DL, Sanders EJ, Peshu NM, Krieger JN, Muller CH, Coombs RW, Fredricks DN, Graham SM. Semen Bacterial Concentrations and HIV-1 RNA Shedding Among HIV-1-Seropositive Kenyan Men. J Acquir Immune Defic Syndr. 2017 Mar 1;74(3):250-257. doi: 10.1097/QAI.0000000000001244. PMCID: PMC5305287.
Balkus JE, Srinivasan S, Anzala O, Kimani J, Andac C, Schwebke J, Fredricks DN, McClelland RS. Impact of Periodic Presumptive Treatment for Bacterial Vaginosis on the Vaginal Microbiome among Women Participating in the Preventing Vaginal Infections Trial. J Infect Dis. 2017 Mar 1;215(5):723-731. doi: 10.1093/infdis/jiw622. PMID: 28007924.
Bajema KL, Dalesandro MF, Fredricks DN, Ramchandani M. Disseminated coccidioidomycosis presenting with intramedullary spinal cord abscesses: Management challenges. Med Mycol Case Rep, 2016 Dec 2;15:1-4. doi: 10.1016/j.mmcr.2016.12.001. eCollection 2017. PMCID: PMC5198726.
2016
Srinivasan S, Munch MM, Sizova MV, Fiedler TL, Kohler CM, Hoffman NG, Liu C, Agnew KJ, Marrazzo JM, Epstein SS, Fredricks DN. More Easily Cultivated Than Identified: Classical Isolation With Molecular Identification of Vaginal Bacteria. J Infect Dis. 2016 Aug 15;214 Suppl 1:S21-8. doi: 10.1093/infdis/jiw192. PMCID: PMC4957512.
Vindigni SM, Taylor J, Quilter LAS, Hyun TS, Liu C, Rosinski SL, Rakita RM, Fredricks DN, Damman CJ. Tropheryma whipplei Infection (Whipple's Disease) in a Patient after Liver Transplant. Transpl Infect Dis. 2016 Aug;18(4):617-24. doi: 10.1111/tid.12562. Epub 2016 Aug 3. PMID: 27258480.
Marty FM, Ostrosky-Zeichner L, Cornely OA, Mullane KM, Perfect JR, Thompson GR, Alangaden GJ, Brown JM, Fredricks DN, et al: Isavuconazole treatment for mucormycosis: open-label trial and contemporaneous case-control analysis. Lancet Infect Dis. 2016 Jul;16(7):828-37. doi: 10.1016/S1473-3099(16)00071-2. Epub 2016 Mar 9. PMID: 26969258
Noecker C, Eng A, Srinivasan S, Theriot C, Young V, Jansson J, Fredricks D, Borenstein E. Metabolic model-based integration of microbiome taxonomic and metabolomic profiles elucidates mechanistic links between ecological and metabolic variation. mSystems. 2016 Jan;1(1):1-17. e00013-15. doi: 10.1128/mSystems.00013-15
2015
Gorgos LM, Sycuro LK, Srinivasan S, Fiedler TL, Morgan MT, Balkus JE, McClelland SR, Fredricks DN, Marrazzo JM. Relationship of Specific Bacteria in the Cervical and Vaginal Microbiotas With Cervicitis. Sex Transm Dis. 2015 Sep;42(9):475-81. doi: 10.1097/OLQ.0000000000000318. PMCID: PMC4590771
Nelson DB, Hanlon AL, Wu G, Liu C, Fredricks DN. First Trimester Levels of BV-Associated Bacteria and Risk of Miscarriage Among Women Early in Pregnancy. Matern Child Health J. 2015 Jul 9. [Epub ahead of print]. PMID: 26156825
Neofytos D, Railkar R, Mullane KM, Fredricks DN, Granwehr B, Marr KA, Almyroudis NG, Kontoyiannis DP, Maertens J, Fox R, Douglas C, Iannone R, Kauh E, Shire N. Correlation between Circulating Fungal Biomarkers and Clinical Outcome in Invasive Aspergillosis. PLoS One. 2015 Jun 24;10(6):e0129022. doi: 10.1371/journal.pone.0129022. eCollection 2015. PMCID: PMC4480423
*Srinivasan S, Morgan MT, Fiedler TL, Djukovic D, Hoffman NG, Raftery D, Marrazzo J, Fredricks DN. Metabolic Signatures of Bacterial Vaginosis. MBio. 2015 Apr 14;6(2). pii: e00204-15. doi: 10.1128/mBio.00204-15. PMCID: PMC4453549
2014
Austin MN, Rabe LK, Srinivasan S, Fredricks DN, Wiesenfeld HC, Hillier SL. Mageeibacillus indolicus gen. nov., sp. nov: A novel bacterium isolated from the female genital tract. Anaerobe. 2015 Apr;32:37-42. doi: 10.1016/j.anaerobe.2014.12.003. Epub 2014 Dec 4. PMCID: PMC4385425
Nelson DB, Hanlon A, Nachamkin I, Haggerty C, Mastrogiannis DS, Liu C, Fredricks DN. Early Pregnancy Changes in Bacterial Vaginosis-Associated Bacteria and Preterm Delivery. Paediatr Perinat Epidemiol. 2014 Mar;28(2):88-96. doi: 10.1111/ppe.12106. Epub 2014 Jan 9. PMID: 24405280
2013
Manhart LE, Khosropour CM, Liu C, Gillespie CW, Depner K, Fiedler T, Marrazzo JM, Fredricks DN. Bacterial vaginosis-associated bacteria in men: association of Leptotrichia/Sneathia spp. with nongonococcal urethritis. Sex Transm Dis. 2013 Dec;40(12):944-9. doi: 10.1097/OLQ.0000000000000054. PMID: 24220356
Nelson DB, Komaroff E, Nachamkin I, Haggerty CL, Dibble L, Mastrogiannis D, Liu C, Fredricks DN. Relationship of selected bacterial vaginosis-associated bacteria to nugent score bacterial vaginosis among urban women early in pregnancy. Sex Transm Dis. 2013 Sep;40(9):721-3. doi: 10.1097/OLQ.0000000000000001. PMID: 23945426
Rickerts V, McCormick Smith I, Mousset S, Kommedal O, Fredricks DN. Deciphering the aetiology of a mixed fungal infection by broadrange PCR with sequencing and fluorescence in situ hybridization. Mycoses. 2013 Nov;56(6):681-6. doi: 10.1111/myc.12083. Epub 2013 Apr 8. PMID: 23560622.
Chu HY, Jain R, Xie H, Pottinger P, Fredricks DN. Voriconazole therapeutic drug monitoring: retrospective cohort study of the relationship to clinical outcomes and adverse events. BMC Infect Dis. 2013, 13:105. DOI: 10.1186/1471-2334-13-105. PMID: 23442261. PMCID: PMC3655856.
2012
Balkus JE, Mitchell C, Agnew K, Liu C, Fiedler T, Cohn SE, Luque A, Coombs R, Fredricks DN, Hitti J. Detection of Hydrogen Peroxide-Producing Lactobacillus Species in the Vagina: a Comparison of Culture and Quantitative PCR Among HIV-1-Seropositive Women. BMC Infect Dis. 2012 Aug 13;12:188. doi: 10.1186/1471-2334-12-188. PMID:22889380. PMCID: PMC3462152.
Kalyoussef S, Nieves E, Dinerman C, Viswanathan S, Oh J, Burd B, Angeletti RH, Buckheit K, Fredricks DN, Madan RP, Keller MJ, Herold BC. Lactobacillus Proteins Are Associated with the Bactericidal Activity against E. coli of Female Genital Tract Secretions. PLoS ONE, 2012;7(11):e49506. doi: 10.1371/journal.pone.0049506. Epub 2012 Nov 19. PMCID: PMC3501525
Mitchell CM, Gottsch M, Liu C, Fredricks DN, Nelson D. Associations between vaginal bacteria and levels of vaginal defensins in pregnant women. Am J Obstet Gynecol 2012 Nov 19. doi:pii: S0002-9378(12)02074-1. 10.1016/j.ajog.2012.11.019. PMID:23174285
Keller MJ, Carpenter CA, Lo Y, Einstein MH, Liu C, Fredricks DN, Herold BC. Phase I Randomized Safety Study of Twice Daily Dosing of Acidform Vaginal Gel: Candidate Antimicrobial Contraceptive. PLoS One 2012;7(10):e46901. doi: 10.1371/journal.pone.0046901. Epub 2012 Oct 8. PMCID: PMC3466198.
Mitchell CM, Fredricks DN, Winer RL, Koutsky L. Effect of Sexual Debut on Vaginal Microbiota in a Cohort of Young Women. Obstet Gynecol. 2012 Dec;120(6):1306-13. doi: http://10.1097/AOG.0b013e31827075ac. PMID:23168754
Pellett Madan R, Carpenter C, Fiedler T, Kalyoussef S, McAndrew TC, Viswanathan S, Kim M, Keller MJ, Fredricks DN, Herold BC. Altered Biomarkers of Mucosal Immunity and Reduced Vaginal Lactobacillus Concentrations in Sexually Active Female Adolescents. PLoS ONE, 7(7): e40415. doi:10.1371/journal.pone.0040415. Epub 2012 Jul 10. PMCID: PMC3393710.
Mitchell C, Manhart LE, Thomas K, Fiedler T, Fredricks DN, Marrazzo J. Behavioral Predictors of Colonization with Lactobacillus crispatus or Lactobacillus jensenii After Treatment for Bacterial Vaginosis: A Cohort Study. Infect Dis Obstet Gynecol, 2012, Article ID 706540, doi:10.1155/2012/706540. PMCID: PMC3369434
Srinivasan S, Hoffman NG, Morgan MT, Matsen FA, Fiedler TL, Hall RW, Ross FJ, McCoy CO, Bumgarner R, Marrazzo JM, Fredricks DN. Bacterial Communities in Women with Bacterial Vaginosis: High Resolution Phylogenetic Analysis Reveals Relationships of Microbiota to Clinical Characteristics. PLoS ONE, 2012;7(6):e37818. doi: 10.1371/journal.pone.0037818. Epub 2012 Jun 18. (Noted paper of importance by Faculty of 1000: http://f1000.com/prime/717747993.) PMCID: PMC3377712.
Spellberg B, Kontoyiannis DP, Fredricks DN, Morris M, Perfect J, Chin-Hong P, Ibrahim AS, Brass EP. Risk Factors for Mortality in Patients with Mucormycosis. Med Mycol. 2012 Aug;50(6):611-8. doi: 10.3109/13693786.2012.669502. Epub 2012 Mar 21. PMID: 22435877 PMCID: PMC3951871.
Rickerts V, Khot PD, Ko DL, Fredricks DN. Enhanced fungal DNA-Extraction from Formalin fixed, paraffin embedded tissue specimens by application of thermal energy. Med Mycol. 2012 Aug;50(6):667-72. doi: 10.3109/13693786.2012.665613. Epub 2012 Mar 13. PMID: 22414380. PMCID: PMC3988784.
Marrazzo JM, Fiedler TL, Srinivasan S, Thomas KK, Liu C, Ko D, Xie H, Saracino M, Fredricks DN. Extravaginal Reservoirs of Vaginal Bacteria as Risk Factors for Incident Bacterial Vaginosis. J Infect Dis. 2012 May 15;205(10):1580-8. doi: 10.1093/infdis/jis242. Epub 2012 Mar 23. PMCID: PMC3415820.
2011
Heugel J, Boeckh M, Huang ML, Dierks B, Hackman R, Fredricks D, Kuypers J, Corey L. Detection of adeno-associated virus viremia in hematopoietic cell transplant recipients. J Infect Dis. 2011 Dec 1;204(11):1746-9. doi: 10.1093/infdis/jir655. Epub 2011 Oct 17. PMCID: PMC3203237.
Ngugi BM, Hemmerling A, Bukusi EA, Kikuvi G, Gikunju J, Shiboski S, Fredricks DN, Cohen CR. Effects of Bacterial Vaginosis-associated Bacteria and Sexual Intercourse on Vaginal Colonization With the Probiotic Lactobacillus crispatus CTV-05. Sex Transm Dis. 2011 Nov;38(11):1020-7. doi: 10.1097/OLQ.0b013e3182267ac4. PMCID: PMC3193282.
Spellberg B, Ibrahim AS, Chin-Hong PV, Kontoyiannis DP, Morris MI, Perfect JR, Fredricks D, Brass EP. The Deferasirox-AmBisome Therapy for Mucormycosis (DEFEAT Mucor) study: a randomized, double-blinded, placebo-controlled trial. J Antimicrob Chemother. 2012 Mar;67(3):715-22. doi: 10.1093/jac/dkr375. Epub 2011 Sep 20. PMCID: PMC3383100.
Fredricks, DN. Molecular methods to describe the spectrum and dynamics of the vaginal microbiota. Anaerobe 2011;17:191-5. PMCID: PMC3126881.
Stapleton AE, Au-Yeung M, Hooton TM, Fredricks DN, Roberts PL, Czaja CA, Yarova-Yarovaya Y, Fiedler T, Cox M, Stamm WE. Randomized, placebo-controlled phase 2 trial of a Lactobacillus crispatus probiotic given intravaginally for prevention of recurrent urinary tract infection. Clin Infect Dis. 2011;52:1212-7. PMCID: PMC3079401.
Rickerts V, Khot PD, Myerson D, Ko DL, Lambrecht E, Fredricks DN. Comparison of quantitative real time PCR with sequencing and ribosomal RNA-FISH for the identification of fungi in formalin fixed, paraffin-embedded tissue specimens. BMC Infect Dis. 2011 Jul 26;11:202. doi: 10.1186/1471-2334-11-202. PMCID: PMC3160998.
2010
*Guthrie KA, Yong M, Frieze D, Corey L, Fredricks DN. The impact of a change in antibacterial prophylaxis from ceftazidime to levofloxacin in allogeneic hematopoietic cell transplantation. Bone Marrow Transplant. 2010 Apr;45(4):675-81. doi: 10.1038/bmt.2009.216. Epub 2009 Aug 31. PMCID: PMC2911962.
*Srinivasan S, Liu C, Mitchell CM, Fiedler TL, Agnew KJ, Thomas KT, Marrazzo JM, Fredricks DN. Temporal variability of human vaginal bacteria and relationship with bacterial vaginosis. PLoS One. 2010; Apr;5(4):e10197. PMCID: PMC2855365.
Marrazzo JM, Thomas KK, Fiedler TL, Ringwood, K, Fredricks DN. Risks for acquisition of bacterial vaginosis among women who report sex with women: a cohort study. PLoS One. 2010 Jun 15;5(6):e11139. doi: 10.1371/journal.pone.0011139. PMCID: PMC2886123.
2009
Khot PD, Ko DL, Fredricks DN. Sequencing and Analysis of Fungal Ribosomal RNA Operons for Development of Broad-Range Fungal PCR Assays. Appl Environ Microbiol. 2009:75;1559-65. PMCID: PMC2655463.
Mitchell C, Moreira C, Fredricks D, Paul K, Caliendo AM, Kurpewski J, Ingersoll J, Cu-Uvin S. Detection of fastidious vaginal bacteria in women with HIV infection and bacterial vaginosis. Infect Dis Obstet Gynecol. 2009;2009:236919. doi: 10.1155/2009/236919. Epub 2009 Nov 12. PMCID: PMC2777244.
Mitchell CM, Hitti JE, Agnew KJ, Fredricks DN. Comparison of oral and vaginal metronidazole for treatment of bacterial vaginosis in pregnancy: impact on fastidious bacteria. BMC Infect Dis. 2009 Jun 10;9:89. doi: 10.1186/1471-2334-9-89. PMCID: PMC2703644.
Nelson DB, Hanlon A, Hassan S, Britto J, Geifman-Holtzman O, Haggerty C, Fredricks DN. Preterm labor and bacterial vaginosis-associated bacteria among urban women. Perinat Med. 2009;37(2):130-4. doi: 10.1515/JPM.2009.026. PMCID: PMC3979329.
Srinivasan S, Fredricks DN. The Human Vaginal Bacterial Biota and Bacterial Vaginosis. Interdiscip Perspect Infect Dis. 2008;2008:750479. doi: 10.1155/2008/750479. Epub 2009 Feb 16. PMCID: PMC2648628.
2008
33. *Marrazzo JM, Thomas KK, Fiedler TL, Ringwood K, Fredricks DN. Relationship of Specific Vaginal Bacteria and Bacterial Vaginosis Treatment Failure in Women Who Have Sex with Women. Ann Intern Med, 2008;149:20-28. PMCID: PMC2630802.
*Khot PD, Ko DL, Hackman RC, Fredricks DN. Development and Optimization of quantitative PCR for the diagnosis of invasive aspergillosis using bronchoalveolar lavage fluid. BioMed Central Infect Dis, 2008;8:73. PMCID: PMC2440748.
Oakley BB, Fiedler TL, Marrazzo JM, Fredricks DN. The Diversity of Human Vaginal Bacterial Communities and their Association with Clinically-Defined Bacterial Vaginosis. Appl Environ Microbiol. 2008 Aug;74(15):4898-909. doi: 10.1128/AEM.02884-07. Epub 2008 May 16. PMCID: PMC2519371.
2007
Fredricks DN, Fiedler TL, Thomas KK, Oakley BB, Marrazzo JM. Targeted Polymerase Chain Reaction for the Detection of Vaginal Bacteria Associated with Bacterial Vaginosis. J Clin Microbiol 2007;45:3270-6. PMCID: PMC2045326.
2006
Fredricks DN, Myerson D. Pneumonia in a patient with leukemia. Infect Dis in Clin Practice 2006;14:107-9.
Sheppard D, Marr KM, Fredricks DN, Chiang L, Doedt T, Filler S. Comparison of three methodologies for the determination of pulmonary fungal burden in experimental murine aspergillosis.Clin Microbiol Infect. 2006 Apr;12(4):376-80. PMID: 16524415.
Englund JA, Boeckh M, Kuypers J, Nichols WG, Hackman RC, Morrow RA, Fredricks DN, Corey L. Fatal human metapneumovirus infection in stem cell transplant recipients. Ann Intern Med 2006;144:344-9. PMID: 16520475.
2005
Fredricks DN, Schubert MM, Myerson D. Molecular identification of an invasive gingival bacterial community. Clin Infect Dis 2005;41:e1-4. PMID: 15937752.
Fredricks DN, Marrazzo JM. Molecular methodology in determining vaginal flora in health and disease; its time has come. Curr Infect Dis Reports 2005;7:463-70. PMID: 16225785.
Fredricks DN, Smith CA, Meier A. Comparison of six DNA extraction methods for recovery of fungal DNA as assessed by quantitative PCR. J Clin Microbiol2005;43:5122-8. PMCID: PMC1248488.
* Fredricks DN, Fiedler T, Marrazzo JM. Molecular identification of bacteria associated with bacterial vaginosis. N Engl J Med. 2005 Nov 3;353(18):1899-911. PMID: 16267321.
2004
Musher B, Fredricks DN, Leisenring W, Balajee A, Smith C, Marr KA. Aspergillus galactomannan Enzyme Immunoassay and Quantitative PCR for the Diagnosis of Invasive Aspergillosis with Bronchoalveolar Lavage Fluid. J Clin Microbiol 2004;42;5517-22. PMCID: PMC535238.
Imhoff A, Balajee A, Fredricks DN, Englund JA, Marr KA. Breakthrough fungal infections in stem cell transplant patients receiving voriconazole. Clin Infect Dis 2004;39:743-6. PMID: 15356792.
2003
Maiwald M, von Herbay A, Fredricks DN, Ouverney CC, Kosek JC, Relman DA. Cultivation of Tropheryma whipplei from cerebrospinal fluid. J Infect Dis. 2003;188:801-8. PMID: 12964110.
2001
Maiwald M, von Herbay A, Persing DH, Mitchell PS, Abdelmalek MF, Thorvilson JN, Fredricks DN, Relman DA. Tropheryma whippelii DNA is rare in the intestinal mucosa of patients without other evidence of Whipple's disease. Ann Intern Med 2001;134:115-19. PMID: 11177314.
Fredricks DN, Relman DA. Localization of Tropheryma whippelii rRNA in tissues from patients with Whipple's disease. J Infect Dis 2001;183:1229-37. PMID: 11262205.
2000 - prior
Fredricks DN, Jolley J, Lepp PW, Kosek J, Relman DA. Rhinosporidium seeberi: A human pathogen from a novel group of aquatic protistan parasites. Emerg Infect Dis 2000; 6:273-82. PMCID: PMC2640875.
Relman DA, Fredricks DN, Yoder KE, Mirowski G, Berger T, Koehler JE. Absence of Kaposi’s sarcoma-associated herpesvirus DNA in bacillary angiomatosis-peliosis lesions. J Infect Dis 1999;180:1386-89. PMID: 10479179.
Fredricks DN, Relman DA. Paraffin removal from tissue sections for PCR analysis. Biotech 1999; 26:198-200. PMID: 10023524.
Fredricks DN, Relman DA. State-of-the-art clinical article: The application of PCR to the diagnosis of infectious diseases. Clin Infect Dis 1999;29:475-86. PMID: 10530433.
Petrides PE, Muller-Hocker J, Fredricks DN, Relman DA. PCR analysis of T. whippelii DNA in a case of Whipple's disease: effect of antibiotics and correlation with histology. Amer Gastroent 1998;(9):1579-82. PMID: 9732952.
Fredricks DN, Relman DA. Improved amplification of microbial DNA from blood cultures by removal of the PCR inhibitor Sodium Polyanetholesulfonate. J Clin Microbiol 1998;36:2810-16. PMCID: PMC105069.
Lynch T, Odel J, Fredricks DN, Louis ED, Forman S, Rotterdam H, Fahn S, Relman DA. Polymerase chain reaction-based detection of Tropheryma whippelii in central nervous system Whipple’s disease. Ann Neurol 1997;42:120-24. PMID: 9225695.
Fredricks DN, Rojanasthien N, Jacobson MA. AIDS-related disseminated histoplasmosis in San Francisco, California.West J Med 1997;167:315-21. PMCID: PMC1304617
Ramzan NN, Loftus E, Burgart LJ, Rooney M, Batts KP, Wiesner RH, Fredricks DN, Relman DA, Persing DH. Diagnosis and monitoring of Whipple’s disease by polymerase chain reaction. Ann Intern Med 1997;126(7):520-7. PMID: 9092317.
Banuelos AF, Williams PL, Johnson RH, Bibi S, Fredricks DN, Gilroy SA, Bhatti SU, Aguet J, Stevens DA. Central nervous system coccidioidal abscesses. Clin Infect Dis 1996;22:240-50. PMID: 8838179.
Fredricks DN, Remington JS. Tularemia presenting as community-acquired pneumonia: implications in the era of managed care. Arch Inter Med 1996;156:2137-40. PMID: 8862107.
Fredricks DN and Relman DA. Sequence-based identification of microbial pathogens: a reconsideration of Koch’s postulates. Clin Microbiol Rev 1996;9:18-33. PMCID: PMC172879.
Wagner JA, Keer H, Fredricks DN. A case of disseminated coccidioidomycosis diagnosed by culture of a central venous catheter tip. Clin Infect Dis 1996;22:180-81. PMID: 8824997
Kirn DH, Fredricks D, McCutchan JA, Stites D, Shuman M. Serum ferritin levels correlate with disease activity in patients with AIDS and disseminated histoplasmosis. Clin Infect Dis 1995;21: 1048-49. PMID: 8645808.
Cole M, Phillipi WE, Fredricks DN. Zoster ataxia with Ramsay Hunt syndrome: case report and a note about treatment. Review of Ecuadorian Neurology 1994;3:24- 27.
Sorensen RU, Fredricks DN, Waller RL. Inhibition of normal and malignant cell proliferation by pyocyanine and 1- hydroxyphenazine. Antibiotics and Chemotherapy 1991; 44: 85-93. PMID: 1801650.
PubMed list of David N Fredricks, MD publications
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