Our Research

The Bone Marrow Transplantation Laboratory uses preclinical transplant models to dissect the immunological mechanisms of transplant complications and aims to improve patient outcome through new therapies to prevent and treat graft-versus-host disease (GVHD), relapse and opportunistic infection. Research focuses on understanding the pathways of alloreactivity resulting in graft-versus-host disease and graft-versus-leukemia (GVL) effects. The ultimate aim is to generate testable therapeutic interventions that attenuate GVHD and improve GVL, without compromise of pathogen-specific immunity.