Our team is cross disciplinary in practice, with collaborators from diverse academic and professional fields, allowing us to effectively design and implement interventions, conduct longitudinal clinical trials and observational research, and evaluate the effectiveness of our programs. Our research uses both clinical trials and observational studies to examine the effects of a wide range of behaviors and interventions on cancer outcomes and survivorship. Interventions of interest target diet, physical activity, weight management, and use of integrative therapies.
The ¡Vida! Study: Using a SMART design to evaluate remotely delivered, community-aligned weight loss interventions among breast cancer survivors
PI: Heather Greenlee, ND, PhD, MPH
NIH/NCI R01CA270441
We are conducting a sequential multiple assignment randomized trial (SMART) testing a 12 month adaptive community-aligned weight loss interventions in a geographically broad group of Latina BC survivors. This research is being conducted in collaboration with investigators from the University of Washington and the University of Pennsylvania.
Pathways Heart Study: Developing CVD prediction models for women with early stage breast cancer
PIs: Heather Greenlee, ND, PhD, MPH
NIH/NCI U01CA214057
We will develop, test, and validate two cardiovascular disease (CVD) risk prediction models, leveraging available clinical and “precision cardio-oncology” data in stage I-III breast cancer patients. This research is being conducted in collaboration with colleagues at Kaiser Permanence Northern California, University of Washington, Roswell Park Cancer Institute, and the National Institute of Environmental Health Sciences.
A Transdisciplinary Approach to Increasing Phytonutrients in New Mexican Diets: A Kitchen-to-Lab-to-Table Model
MPIs: Heather Greenlee, ND, PhD, MPH and Ivette Guzman, PhD
NIH/NCI U54CA132391
We are collaborating with investigators at New Mexico State University (NMSU) and the NMSU Cooperative Extension Service to develop and implement a “kitchen-to-lab-to-table” research model. We are assessing the bioavailability of cancer protective phytonutrients in traditional New Mexican foods, and we are developing a community-based curriculum focused on increasing cancer protective phytonutrients in New Mexican diets.
Tribal Wellness and Cancer Nutrition Initiative | Washington State Andy Hill CARE Fund
MPIs: Heather Greenlee, ND, PhD, MPH and Mandy Fretts, PhD
We are collaborating with investigators at the University of Washington to engage Tribal communities and organizations to 1) conduct key informant interviews on resources for nutrition and cancer and develop a Community Advisory Board (CAB); 2) use a strengths-based approach to develop and culturally adapt existing nutrition education resources for cancer prevention and survivorship for American Indians and Alaska Natives in Washington State, and 3) identify culturally appropriate and feasible methods to assess biomarkers of fruit/vegetable intake in American Indians and Alaska Natives in Washington State.