Vaccine and Infectious Disease Division
Public Health Sciences Division
Fred Hutchinson Cancer Research Center
Department of Biostatistics
University of Washington
The major research interest of our group is to develop efficient and robust statistical methods for design and analysis of biomarker studies for the purpose of disease screening, surrogate endpoint identification, and treatment selection in cancer and infectious diseases. Biomarkers are subject characteristics that can help to predict the risk of diseases and/or the effect of treatment. We study how to efficiently select biomarkers among high-dimensional candidates and derive marker-based individualized rules, using data from randomized trials and observational studies.