View the Ring Lab's full bibliography on PubMed.

2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2017 | 2016 | 2015 | 2013 | 2012

2025

• Dai Y, Aizenbud L, Qin K, Austin M, Jaycox JR, Cunningham J, Wang EY, Zhang L, Fischer S, Carroll SM, van Aggelen H, Kluger Y, Herold KC, Furchtgott L*, Kluger HM*, Ring AM*. Humoral determinants of checkpoint immunotherapy. Nature. 2025. 
  *Corresponding authors

2024

• Schoenfeld DA, Djureinovic D, Su DG, Zhang L, L BY, Kamga L, Mann JE, Huck JD, Hurwitz M, Braun DA, Jilaveanu L, Ring AM*, Kluger HM*. Decoy-resistant IL-18 reshapes the tumor microenvironment and enhances rejection by anti-CTLA-4 in renal cell carcinoma. JCI Insight. 2024;10(1). *Corresponding authors.
• Marin-Lopez A*, Huck JD, Esterly AT, Azcutia V, Rosen C, Garcia-Milian R, Sefik E, Vidal-Pedrola G, Raduwan H, Chen TY, Arora G, Halene S, Shaw AC, Palm NW, Flavell RA, Parkos CA, Thangamani S, Ring AM*, Fikrig E*. The human CD47 checkpoint is targeted by an immunosuppressive Aedes aegypti salivary factor to enhance arboviral skin infectivity. Sci Immunol. 2024;9(98):eadk9872. *Corresponding authors
• Hart TM, Sonnert ND, Tang X, Chaurasia R, Allen P, Hunt JR, Read CB, Johnson EE, Arora G, Dai Y, Cui Y, Chuang YM, Yu Q, Rahman MS, Mendes MT, Rolandelli A, Singh P, Tripathi A, Mamoun C, Caimano M, Radolf JD, Lin YP, Fingerle V, Margos G, Pal U, Johnson RM, Pedra JHF, Azad AF, Salje J, Dimopoulos G, Vinetz JM, Carlyon JA*, Palm NW*, Fikrig E*, Ring AM*. An atlas of human vector-borne microbe interactions reveals pathogenecity mechanisms. Cell. 2024;187(15):4113-27 e13. *Corresponding authors
• Sonnert N.D., Rosen C.E., Ghazi A.R., Franzosa E.A., Duncan-Lowey B., González-Hernández J.A., Huck J.D., Yang Y., Dai Y., Rice T.A., Nguyen M.T., Song D., Cao Y., Martin A.L., Bielecka A.A., Fischer S., Guan C., Oh J., Huttenower C., Ring A.M.*, Palm N.W.* A host-microbiota interactome reveals extensive transkingdom connectivity. Nature. 2024 Mar 20. Online ahead of print. *Corresponding authors     
• Jaycox, J. R., Dai, Y., Ring, A. M. Decoding the autoantibody reactome. Science. 2024; 383, 705-707. PMID: 38359108.

2023

• Klein J, Wood J, Jaycox J, Lu P, Dhodapkar RM, Gehlhausen JR, Tabachnikova A, Tabacof L, Malik AA, Kamath K, Greene K, Monteiro VS, Peña-Hernandez M, Mao T, Bhattacharjee B, Takahashi T, Lucas C, Silva J, Mccarthy D, Breyman E, Tosto-Mancuso J, Dai Y, Perotti E, Akduman K, Tzeng TJ, Xu L, Yildirim I, Krumholz HM, Shon J, Medzhitov R, Omer SB, van Dijk D*, Ring AM*, Putrino D*, Iwasaki A*. Distinguishing features of Long COVID identified through immune profiling. Nature. 2023. In press.
  *Corresponding authors
• Jaycox JR, Lucas C, Yildirim I, Dai Y, Wang EY, Monteiro V, Lord S, Carlin J, Kita M, Buckner JH, Ma S, Campbell M, Ko A, Omer S, Lucas CL, Speake C*, Iwasaki A*, Ring AM*. SARS-CoV-2 mRNA vaccines decouple antiviral immunity from humoral autoimmunity. Nat. Commun. 2023 Mar 9; 14:1299. PMID: 36894554.
  *Corresponding authors
• Clark JT, Weizman OE, Aldridge DL, Shallberg LA, Eberhard J, Lanzar Z, Wasche D, Huck JD, Zhou T, Ring AM*, Hunter CA*. IL-18BP mediates the balance between protective and pathological immune responses to Toxoplasma gondii. Cell Rep. 2023 Feb 22;42(3):112147. PMID: 36827187.
  *Corresponding authors

2022

• Wang E.Y., Dai, Y., Rosen, C.E., Schmitt, M.M., Dong, M.X., Ferre, E.M.N., Liu, F., Yang, Y., Gonzalez-Hernandez, J.A., Meffre, E., Hinchcliffe, M., Koumpouras, F., Lionakis, M.S., Ring, A.M. High-throughput identification of autoantibodies that target the human exoproteome. Cell Reports Methods. 2022 Feb 28; 2(2):100172. PMID: 35360706.
• Arora G, Lynn GE, Tang X, Rosen CE, Hoornstra D, Sajid A, Hovius JW, Palm NW*, Ring AM*, Fikrig E*. CD55 Facilitates Immune Evasion by Borrelia crocidurae, an Agent of Relapsing Fever. mBio. 2022 Oct 26;13(5):e0116122. PMID: 36036625.
  *Corresponding authors

2021

• Wang E.Y., Mao T., Klein J., Dai Y., Huck J.D., Liu F., Zheng N.S., Zhou T., Israelow B., Wong P., Lucas C., Silva J., Oh J.E., Song E., Perotti E.S., Fischer S., Campbell M., Fournier J.B., Wyllie A.L., Vogels C.B.F., Ott I.M., Kalinich C.C., Petrone M.E., Watkins A.E., Cruz C.D., Farhadian S.F., Schulz W.L., Grubaugh N.D., Ko A.I., Iwasaki A.*, Ring A.M.* Diverse Functional Autoantibodies in Patients with COVID-19. Nature. 2021 Jul;595(7866):283-288. PMID: 34010947.
  *Corresponding authors

2020

• Zhou, T., Damsky, W., Weizman, O., McGeary, M.K., Hartmann, K.P., Rosen, C.E., Fischer, S., Jackson, R., Flavell, R.A., Wang, J., Sanmamed, M.F., Bosenberg, M.W., Ring, A.M. (2020). IL-18BP is a secreted immune checkpoint and barrier to IL-18 immunotherapy. Nature. 2020; 583(7817):609-614. PMID: 32581358.
• Gupta A., Arora G., Rosen C.E., Kloos Z., Cao Y., Cerny J., Sajid A., Hoornstra D., Golovchenko M., Rudenko N., Munderloh U., Hovius J.W., Booth C.J., Jacobs-Wagner C., Palm N.W.*, Ring A.M.*, Fikrig E.* A human secretome library screen reveals a role for Peptidoglycan Recognition Protein 1 in Lyme borreliosis. PLoS Pathog. 2020 Nov 11;16(11):e1009030. PMID: 33175909.
  *Corresponding authors

2017

• Ring N.G., Herndler-Brandstetter D., Weiskopf K., Shan L., Volkmer J.P., George B.M., Lietzenmayer M., McKenna K.M., Naik T.J., McCarty A., Zheng Y., Ring A.M.*, Flavell R.A.*, Weissman I.L.* Anti-SIRPα antibody immunotherapy enhances neutrophil and macrophage antitumor activity. Proc Natl Acad Sci, U S A. 2017; 114(49):E10578-E10585.
  *Equal contributors

2016

• Chhabra, A.*, Ring, A.M.*, Weiskopf, K.*, Schnorr, P.J., Gordon, S., Le, A.C., Kwon, H., Ring, N.G., Volkmer, J., Ho, P.Y., Tseng, S., Weissman, I.L., Shizuru, J.A. Hematopoietic stem cell transplantation in an immunocompetent host without radiation or chemotherapy. Sci. Transl. Med. 2016; 8(351):351ra105.
  *Equal contributors

2015

• Mitra, S*, Ring, A.M.*, Amarnath, S., Spangler, J.B., Li, P., Ju, W., Fischer, S., Oh, J., Spolski, R., Weiskopf, K., Kohrt, H., Foley, J.E., Rajagopalan, S., Long, E.O., Fowler, D.H., Waldmann, T.A., Garcia, K.C., and Leonard, W.J. Interleukin-2 activity can be fine tuned with engineered receptor signaling clamps. Immunity. 2015; 42(5): 826-838.
  *Equal contributors
  
• Maute, R.L., Gordon, S.G., Mayer, A.T., McCracken, M.N., Natarajan, A., Ring, N.G., Kimura, R., Tsai, J.M., Manglik, A., Kruse, A.C., Gambhir, S.S., Weissman, I.L.*, Ring, A.M.* Engineering high-affinity PD-1 variants for optimized immunotherapy and immuno-PET imaging. Proc Natl Acad Sci, U S A. 2015; 112(47):E6506-14.
  *Corresponding authors

2013

• Weiskopf, K.*, Ring, A.M.*, Ho, C.C.M., Volkmer, J., Levin, A.M., Volkmer, A.K., Ozkan, E., Fernoff, N.B., van de Rijn, M., Weissman, I.L., and Garcia, K.C. Engineered SIRPα variants as immunotherapeutic adjuvants to anti-cancer antibodies. Science. 2013, 341(6141): 88-91.
  *Equal contributors
• Ring, A.M.*, Manglik, A.*, Kruse, A.C.*, Enos, M.D., Weis, W.I., Garcia, K.C., and Kobilka, B.K. Adrenaline-activated structure of β2-adrenoceptor stabilized by an engineered nanobody. Nature. 2013; 502(7472):575-579.
  *Equal contributors
• Kruse, A.C.*, Ring, A.M.*, Manglik, A., Hu, J., Hu, H., Eitel, K., Hübner, H., Pardon, E., Valant, C., Sexton, P.M., Christopoulos, A., Felder, C.C., Gmeiner, P., Steyaert, J., Weis W.I., Garcia, K.C., Wess, J., Kobilka, B.K. Activation and allosteric modulation of a muscarinic acetylcholine receptor. Nature. 2013; 504(7478): 101-6.
  *Equal contributors

2012

• Ring, A.M., Lin, J.X., Feng, D., Mitra, S., Rickert, M., Bowman, G.R., Pande, V.S., Li, P., Moraga, I., Spolski, R. , Ozkan, E., Leonard, W.J., and Garcia, K.C. Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15. Nature Immunology. 2012; 13(12): 1187-95.
• Levin, A.M.*, Bates, D.L.*, Ring, A.M.*, Krieg, C.*, Lin, J.T., Su, L., Moraga, I., Raeber, M.E., Bowman, G.R., Novick, P., Pande, V.S., Fathman, C.G., Boyman, O., and Garcia, K.C. Exploiting a natural conformational switch to engineer an interleukin-2 ‘superkine’. Nature. 2012; 484(7395): 529–533.
  *Equal contributors