Visit PubMed to view Dr. Derek Stirewalt's publication record.
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Othus M, Estey EH, Garcia-Manero G, Wood BL, Stirewalt DL, Godwin JE, Weick JK, Anderson JE, Appelbaum FR, Erba HP, Walter RB. Second cycle remission achievement with 7+3 and survival in adults with newly diagnosed acute myeloid leukemia: analysis of recent SWOG trials. Leukemia. 2019;33(2):554:558. doi: 10.1038/s41375-018-0274-y. Epub 2018 Oct 12. PMID: 30315233. PMCID: PMC6367002.
Pogosova-Agadjanyan EL, Moseley A, Othus M, Appelbaum FR, Chauncey TR, Chen IL, Erba HP, Godwin JE, Fang M, Kopecky KJ, List AF, Pogosov GL, Radich JP, Willman CL, Wood BL, Meshinchi S, Stirewalt DL. Impact of specimen heterogeneity on biomarkers in repository samples from patients with acute myeloid leukemia: A SWOG report. Biopreserv Biobank. 2018;16(1):42-52. doi: 10.1089/bio.2017.0079. Epub 2017 November 27. PMID: 29172682. PMCID: PMC5808392.
Halpern AB, Othus M, Heubner EM, Buckley SA, Pogosova-Agadjanyan EL, Orlowski KF, Scott BL, Becker PS, Hendrie PC, Chen TL, Percival MM, Estey EH, Stirewalt DL, Walter RB. Mitoxantrone, etoposide, and cytarabine (MEC) following epigenetic priming with decitabine in adults with relapsed/refractory acute myeloid leukemia or other high-grade myeloid neoplasms: a phase 1/2 study. Leukemia. 2017;31(12):2560-67. PMID 28555084. PMCID: PMC5709258.
VanderWalde N, Jagsi R, Dotan E, Baumgartner J, Browner IS, Burhenn P, Cohen HJ, Edil BH, Edwards B, Extermann M, Ganti AK, Gross C, Hubbard J, Keating NL, Korc-Grodzicki B, McKoy JM, Medeiros, BC, Mrozek E, O’Connor T, Rugo HS, Rupper RW, Shepard D, Silliman RA, Stirewalt DL, Tew WP, Walter LC, Wildes T, Bergman MA, Sundar H, Hurria A. NCCN Guidelines Insights: Older Adult Oncology, Version 2.2016 [review]. J Natl Compr Canc Netw. 2016;14(11):1357-1370. PMID 27799507.
Othus M, Wood BL, Stirewalt DL, Estey EH, Petersdorf SH, Appelbaum FR, Erba HP, Walter RB. Effect of measurable (“minimal”) residual disease (MRD) information on prediction of relapse and survival in adult acute myeloid leukemia. Leukemia. 2016;30(10):2080-2083. PMID: 27133827. PMCID: PMC5053842.
Kennedy JJ, Yan P, Zhao L, Ivey RG, Voytovich UJ, Moore HD, Lin C, Pogosova-Agadjanyan EL, Stirewalt DL, Reding KW, Whiteaker JR, Paulovich AG. Immobilized metal affinity chromatography coupled to multiple reaction monitoring enables reproducible quantification of phospho-signaling. Mol Cell Proteomics. 2016;15(2):726-39. PMC: 26621847. PMCID: PMC4739685.
Ostronoff F, Othus M, Lazenby M, Estey E, Appelbaum FR, Evans A, Godwin J, Gilkes A, Kopecky KJ, Burnett A, List AF, Fang M, Oehler VG, Petersdorf SH, Pogosova-Agadjanyan EL, Radich JP, Willman CL, Meshinchi S, Stirewalt DL. Prognostic significance of NPM1 mutations in the absence of FLT3-internal tandem duplication in older patients with acute myeloid leukemia: a SWOG and UK National Cancer Research Institute/Medical Research Council report. J Clin Oncol. 2015;33(10):1157-64. PMID: 25713434. PMCID: PMC4372852.
Qu X, Davison J, Du L, Storer B, Stirewalt DL, Heimfeld S, Estey E, Appelbaum FR, Fang M. Identification of differentially methylated markers among cytogenetic risk groups of acute myeloid leukemia. Epigenetics. 2015;10(6):526-35. PMC: 25996682. PMCID: PMC4623036.
Hsu CH, Nguyen C, Yan C, Ries RE, Chen QR, Hu Y, Ostronoff F, Stirewalt DL, Komatsoulis G, Levy S, Meerzaman D, Meshinchi S. Transcriptome Profiling of Pediatric Core Binding Factor AML. PLoS One. 2015;10(9):e0138782. PMID: 26397705. PMCID: PMC4580636.
Dvinge H, Ries RE, Ilagan JO, Stirewalt DL, Meshinchi S, Bradley RK. Sample processing obscures cancer-specific alterations in leukemic transcriptomes. Proc Natl Acad Sci U S A. 2014;111(47):16802-07. PMID: 25385641.PMCID: PMC4250124.
Chevillet JR, Kang Q, Ruf IK, Briggs HA, Vojtech, LN, Hughes, SM, Cheng HH, Arroyo JD, Meredith EK, Gallichotte EN, Pogosova-Agadjanyan EL, Morrissey C, Stirewalt DL, Hladik F, Yu EY, Higano CS, Tewari M. Quantitative and stoichiometric analysis of the microRNA content of exosomes. Proc Natl Acad Sci U S A. 2014;111(41):14888-93. PMID: 25267620. PMCID: PMC4205618.
Stirewalt DL, Pogosova-Agadjanyan EL, Tsuchiya K, Joaquin J, Meshinchi S. Copy-neutral loss of heterozygosity is prevalent and a late event in the pathogenesis of FLT3/ITD AML. Blood Cancer J. 2014;4:e208. PMID: 24786392. PMCID: PMC4042297.
Moore HD, Ivey RG, Voytovich UJ, Lin C, Stirewalt DL, Pogosova-Agadjanyan EL, Paulovich AG. The human salivary proteome is radiation responsive. Radiat Res. 2014;181(5):521-30. PMID: 24720749. PMCID: PMC4110973.
Wildes TM, Stirewalt DL, Medeiros B, Hurria A. Hematopoietic stem cell transplantation for hematologic malignancies in older adults: geriatric principles in the transplant clinic [review]. J Natl Compr Canc Netw. 2014;12(1):128-36. PMID: 24453296. PMCID: PMC4010196.
Hurria A, Wildes T, Blair SL, Browner IS, Cohen HJ, Deshazo M, Dotan E, Edil BH, Extermann M, Ganti AK, Holmes HM, Jagsi R, Karlekar MB, Keating NL, Korc-Grodzicki B, McKoy JM, Medeiros BC, Mrozek E, O'Connor T, Rugo HS, Rupper RW, Silliman RA, Stirewalt DL, Tew WP, Walter LC, Weir AB 3rd, Bergman MA, Sundar H. Senior adult oncology, version 2.2014: clinical practice guidelines in oncology [review]. J Natl Compr Canc Netw. 2014;12(1):82-126. PMID: 24453295.
Morris VA, Zhang A, Yang T, Stirewalt DL, Ramamurthy R, Meshinchi S, Oehler VG. MicroRNA-150 expression induces myeloid differentiation of human acute leukemia cells and normal hematopoietic progenitors. PLoS One. 2013;8(9):e75815. PMID: 24086639. PMCID: PMC3782459.
Pogosova-Agadjanyan EL, Kopecky KJ, Ostronoff F, Appelbaum FR, Godwin J, Lee H, List AF, May JJ, Oehler VG, Petersdorf S, Pogosov GL, Radich JR, Willman CL, Meshinchi S, Stirewalt DL. The prognostic significance of IRF8 transcripts in adult patients with acute myeloid leukemia. PLoS One. 2013; 8(8):e70812. PMID: 23967110. PMCID: PMC3743845.
Ostronoff F, Othus M, Kantarjian HM, Meshinchi S, Ravandi F, Hendrie P, Faderl S, Becker PS, Cortes JE, Pagel JM, Petersdorf SH, Godwin JE, Willman CL, Pierce SA, List AF, Sandhu RK, Walter RB, Stirewalt DL, Appelbaum FR, Estey EH. A model for prediction of FLT3-ITD and NPM1 (without FLT3-ITD) positivity in patients with newly diagnosed acute myeloid leukaemia. Br J Haematol. 2013;163(1):130-2. PMID: 23829510. PMCID: PMC4128010.
Ostronoff F, Othus M, Ho PA, Kutny M, Geraghty DE, Petersdorf SH, Godwin JE, Willman CL, Radich JP, Appelbaum FR, Stirewalt DL, Meshinchi S. Mutations in the DNMT3A exon 23 independently predict poor outcome in older patients with acute myeloid leukemia: a SWOG report. Leukemia. 2013;27(1):238-41. PMID: 22722750. PMCID: PMC4457316.
Foss EJ, Radulovic D, Stirewalt DL, Radich J, Sala-Torra O, Pogosova-Agadjanyan EL, Hengel SM, Loeb KR, Deeg HJ, Meshinchi S, Goddlett DR, Bedalov A. Proteomic classification of acute leukemias by alignment-based quantification of LC-MS/MS data sets. J Proteome Res. 2012;11(10):5005-10. PMID: 22900933. PMCID: PMC3564549.
Deeg HJ, Scott BL, Fang M, Shulman HM, Gyurkocza B, Myerson D, Pagel JM, Platzbecker U, Ramakerishnan A, Radich JP, Sandmaier BM, Sorror M, Stirewalt DL, Wilson WA, Storb R, Appelbaum FR, Gooley T. Five-group cytogenetic risk classification, monosomal karyotype and outcome after hematopoietic cell transplantation for MDS or acute leukemia evolving from MDS. Blood. 2012;120(7):1398-408. PMID: 22767498. PMCID: PMC3478516.
Ochsenreither S, Majeti R, Schmitt T, Stirewalt D, Keiholz U, Loeb KR, Wood B, Choi YE, Bleakley M, Warren EH, Hudecek M, Akatsuka Y, Weissman IL, Greenberg PD. Cyclin-A1 represents a new immunogenic targetable antigen expressed in acute myeloid leukemia stem cells with characteristics of a cancer-testis antigen. Blood. 2012;119(23):5492-501. PMD: 22529286. PMCID: PMC3369684.2
Ho PA, Kopecky KJ, Alonzo TA, Gerbing RB, Miller KL, Kuhn J, Zeng R, Ries RE, Raimondi SC, Hirsch BA, Oehler V, Hurwitz CA, Franklin JL, Gamis AS, Petersdorf SH, Anderson JE, Godwin JE, Reaman GH, Willman CL, Bernstein ID, Radich JP, Appelbaum FR, Stirewalt DL, Meshinchi S. Prognostic implications of the IDH1 synonymous SNP rs11554137 in pediatric and adult AML: report from the Children's Oncology Group and SWOG. Blood. 2011;118(17):4561-6. PMID: 21873548. PMCID: PMC3208275.
Becker PS, Kantarjian HM, Appelbaum FR, Petersdorf SH, Storer B, Pierce S, Shan J, Hendrie PC, Pagel JM, Shustov AR, Stirewalt DL, Faderl S, Harrington E, Estey EH. Clofarabine with high dose cytarabine and granulocyte colony-stimulating factor (G-CSF) priming for relapsed and refractory acute myeloid leukaemia. Br J Haematol. 2011;155(2):182-9. PMID: 21848522. PMCID: PMC4834701.
Fan W, Stirewalt DL, Radich JP, Zhao L. Comparison of two methods for detecting alternative splice variants using GeneChip® Exon Arrays. Int J Biomed Sci. 2011;7(3):172-80. PMID: 23675234. PMCID: PMC3614835.
Ivey RG, Moore HD, Voytovich UJ, Thienes CP, Lorentzen TD, Pogosova-Agadjanyan EL, Frayo S, Izaguirre VK, Lunberg SJ, Hedin L, Badiozamani KR, Hoofnagle AN, Stirewalt DL, Wang P, Georges GE, Gopal AK, Paulovich AG. Blood-based detection of radiation exposure in humans based on novel phospho-Smc1 ELISA. Radiat Res. 2011;175(3):266-81. PMID: 21388270. PMCID: PMC3123689.
Arroyo JD, Chevillet JR, Kroh EM, Ruf IK, Pritchard CC, Gibson DF, Mitchell PS, Bennett CF, Pogosova-Agadjanyan EL, Stirewalt DL, Tait JF, Tewari M. Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma. Proc Natl Acad Sci U S A. 2011;108(12):5003-8. PMID: 21383194. PMCID: PMC3064324.
Pogosova-Agadjanyan EL, Fan W, Georges GE, Schwartz JL, Kepler CM, Lee H, Suchanek AL, Cronk MR, Brumbaugh A, Engel JH, Yukawa M, Zhao LP, Heimfeld S, Stirewalt DL. Identification of radiation-induced expression changes in nonimmortalized human T-cells. Radiat Res. 2011;175(2):172-84. PMID: 21268710. PMCID: PMC3136539.
Newell LF, Gooley T, Hansen JA, Stirewalt DL, Petersdorf EW, Deeg HJ. Tumor necrosis factor polymorphism affects transplant outcome in patients with myelodysplastic syndrome but not in those with chronic myelogenous leukemia, independent of the presence of HLA-DR15. Biol Blood Marrow Transplant. 2010;16(12):1700-06. PMID: 20541027. PMCID: PMC2975858.
Ho PA, Zeng R, Alonzo TA, Gerbing RB, Miller KL, Pollard JA, Stirewalt DL, Heerema NA, Raimondi SC, Hirsch B, Franklin JL, Lange B, Meshinchi S. Prevalence and prognostic implications of WT1 mutations in pediatric acute myeloid leukemia (AML): a report from the Children's Oncology Group. Blood. 2010;116(5):702-10. PMID: 20413658. PMCID: PMC2918327.
Ho PA, Alonzo TA, Kopecky KJ, Miller KL, Kuhn J, Zeng R, Gerbing RB, Raimondi SC, Hirsch BA, Oehler V, Hurwitz CA, Franklin JL, Gamis AS, Petersdorf SH, Anderson JE, Reaman GH, Baker LH, Willman CL, Bernstein ID, Radich JP, Appelbaum FR, Stirewalt DL, Meshinchi S. Molecular alterations of the IDH1 gene in AML: a Children's Oncology Group and Southwest Oncology Group study. Leukemia. 2010;24(5):909-13. PMID: 20376086. PMCID: PMC2945692.
Stirewalt DL, Meshinchi S. Receptor tyrosine kinase alterations in AML - biology and therapy. In: Nagarajan L. (eds) Acute Myelogenous Leukemia. Cancer Treatment and Research. Vol 145. New York, NY: Springer; 2010: 85-108. doi: 10:1007/978-0-387-69259-3_6. PMID:20306247.
Oehler VG, Guthrie KA, Cummings CL, Sabo K, Wood BL, Gooley T, Yang T, Epping MT, Shou Y, Pogosova-Agadjanyan E, Ladne P, Stirewalt DL, Abkowitz JL, Radich JP. The preferentially expressed antigen in melanoma (PRAME) inhibits myeloid differentiation in normal hematopoietic and leukemic progenitor cells. Blood. 2009;114(15):3299-308. PMID: 19625708. PMCID: PMC2759652.
Lionberger JM, Stirewalt DL. Gene expression changes in normal haematopoietic cells. Best Pract Res Clin Haematol. 2009;22(2):249-69. PMID: 19698932.
Ho PA, Alonzo TA, Gerbing RB, Pollard J, Stirewalt DL, Hurwitz C, Heerema NA, Hirsch B, Raimondi SC, Lange B, Franklin JL, Radich JP, Meshinchi S. Prevalence and prognostic implications of CEBPA mutations in pediatric acute myeloid leukemia (AML): a report from the Children's Oncology Group. Blood. 2009;113(26):6558-66. PMID: 19304957. PMCID: PMC2943755.
Hochhaus A, O'Brien SG, Guilhot F, Druker BJ, Branford S, Foroni L, Goldman JM, Müller MC, Radich JP, Rudoltz M, Mone M, Gathmann I, Hughes TP, Larson RA; IRIS Investigators (including Stirewalt DL). Six-year follow-up of patients receiving imatinib for the first-line treatment of chronic myeloid leukemia. Leukemia. 2009;23(6):1054-61. doi: 10.1038/leu.2009.38. PMID: 19282833.
Stirewalt DL, Choi YE, Sharpless NE, Pogosova-Agadjanyan EL, Cronk MR, Yukawa M, Larson EB, Wood BL, Appelbaum FR, Radich JP, Heimfeld S. Decreased IRF8 expression in aging hematopoietic progenitor/stem cells. Leukemia. 2009;23(2):391-3. PMID: 18596738. PMCID: PMC2640437.
Kantarjian HM, Larson RA, Guilhot F, O'Brien SG, Mone M, Rudoltz M, Krahnke T, Cortes J, Druker BJ; International Randomized Study of Interferon and STI571 (IRIS) Investigators (including Stirewalt DL). Efficacy of imatinib dose escalation in patients with chronic myeloid leukemia in chronic phase. Cancer. 2009;115(3):551-60. PMID: 19117345. PMCID: PMC4445370.
Becker PS, Kopecky KJ, Wilks AN, Chien S, Harlan JM, Willman CL, Petersdorf SH, Stirewalt DL, Papayannopoulou T, Appelbaum FR. Very late antigen-4 (VLA-4) function of myeloblasts correlates with improved overall survival for patients with acute myeloid leukemia. Blood. 2009;113(4):866-74. PMID: 18927435. PMCID: PMC2630271.
Mitchell PS, Parkin RK, Kroh EM, Fritz BR, Wyman SK, Pogosova-Agadjanyan EL, Peterson A, Noteboom J, O’Briant KC, Allen A, Li DW, Urban N, Drescher CW, Knudsen BS, Stirewalt DL, Gentleman R, Vessella RL, Nelson PS, Martin DB, Tewari M. Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci U S A. 2008;105(30):10513-8. PMID: 18663219. PMCID: PMC2492472.
Meshinchi S, Stirewalt DL, Alonzo TA, Boggon TJ, Gerbing RB, Rocnik JL, Lange BJ, Gilliland DG, Radich JP. Structural and numerical variation of FLT3/ITD in pediatric AML. Blood. 2008;111(10):4930-3. PMID: 18305215. PMCID: PMC2384125.
Bar M, Stirewalt D, Pogosova-Agadjanyan E, Wagner V, Gooley T, Abbasi N, Bhatia R, Deeg HJ, Radich J. Gene expression patterns in myelodysplasia underline the role of apoptosis and differentiation in disease initiation and progression. Transl Oncogenomics. 2008;3:137-49. PMID: 20396593. PMCID: PMC2854514.
Larson RA, Druker BJ, Guilhot F, O'Brien SG, Riviere GJ, Krahnke T, Gathmann I, Wang Y; IRIS (International Randomized Interferon vs STI571) Study Group (including Stirewalt DL). Imatinib pharmacokinetics and its correlation with response and safety in chronic-phase chronic myeloid leukemia: a subanalysis of the IRIS study. Blood. 2008;111(8):4022-8. doi: 10.1182/blood-2007-10-116475. PMID: 18256322.
Marcondes AM, Mhyre AJ, Stirewalt DL, Kim SH, Dinarello CA, Deeg HJ. Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function. Proc Natl Acad Sci U S A. 2008;105(8):2865-70. PMCID: PMC2268551.
Stirewalt DL, Mhyre AJ, Marcondes M, Pogosova-Agadjanyan E, Abbasi N, Radich JP, Deeg HJ. Tumour necrosis factor-induced gene expression in human marrow stroma: clues to the pathophysiology of MDS? Br J Haematol. 2008;140(4):444-53. doi: 10.1111/j.1365-2141.2007.06923.x. PMID: 18162123.
Stirewalt DL, Meshinchi S, Kopecky KJ, Fan W, Pogosova-Agadjanyan EL, Engel JH, Cronk MR, Dorcy KS, McQuary AR, Hockenbery D, Wood B, Heimfeld S, Radich JP. Identification of genes with abnormal expression in acute myeloid leukemia. Genes Chromosome Cancer. 2008;47(1):8-20. PMID: 17910043.
Sala-Torra O, Gundacker HM, Stirewalt DL, Ladne PA, Pogosova-Agadjanyan EL, Slovak ML, Willman CL, Heimfeld S, Boldt DH, Radich JP. Connective tissue growth factor (CTGF) expression and outcome in adult patients with acute lymphoblastic leukemia. Blood. 2007;109(7):3080-3. PMID: 17170128. PMCID: 1852221.
Kornblau SM, Banker DE, Stirewalt D, Shen D, Lemker E, Verstovsek S, Estrov Z, Faderi S, Cortes J, Beran M, Jackson CE, Chen W, Estey E, Appelbaum FR. Blockade of adaptive defensive changes in cholesterol uptake and synthesis in AML by the addition of pravastatin in idarubicin + high dose Ara-C: a phase 1 study. Blood. 2007;109(7):2999-3006. PMID: 17158228. PMCID: PMC1852228.
Kerbauy DMB, Gooley TA, Sale GE, Flowers MED, Doney KC, Georges GE, Greene JE, Linenberger M, Petersdorf E, Sandmaier BM, Scott BL, Stirewalt DL, Stewart FM, Witherspoon RP, Storb R, Appelbaum FR, Deeg HJ. Hematopoietic cell transplantation as curative therapy for idiopathic myelofibrosis, advanced polycythemia vera, and essential thrombocythemia. Biol Bone Marrow Transplant. 2007;13(3):355-65. PMID: 17317589. doi: 10.1016/j.bbmt.2006.11.004.
Bellido M, Stirewalt DL, Zhao LP, Radich JP. Use of gene expression microarrays for the study of acute leukemia. Expert Rev Mol Diagn. 2006;6(5):733-47. PMID: 17009907. doi: 10.1586/14737159.6.5.733.
Meshinchi S, Alonzo TA, Stirewalt DL, Zwaan CM, Zimmerman M, Reinhardt D, Kaspers GJL, Heerema NA, Gerbing RB, Lange BJ, Radich JP. Clinical implications of FLT3 mutations in pediatric AML. Blood. 2006;108(12):3654-61. PMID: 16912228. PMCID: PMC1895470.
Wilson CS, Davidson GS, Martin SB, Andries E, Potter J, Harvey R, Ar K, Xu Y, Kopecky KJ, Ankerst DP, Gundacker H, Slovak ML, Mosquera-Caro M, Chen IM, Stirewalt DL, Murphy M, Schultz FA, Kang H, Wang X, Radich JP, Appelbaum FR, Atlas SR, Godwin J, Willman CL. Gene expression profiling of adult acute myeloid leukemia identifies novel biologic clusters for risk classification and outcome prediction. Blood. 2006;108(2):685-96. PMID: 16597596. PMCID: PMC1895492.
Stirewalt DL, Kopecky KJ, Meshinchi S, Engel JH, Pogosova-Agadjanyan EL, Linsley J, Slovak ML, Willman CL, Radich JP. Size of FLT3 internal tandem duplication has prognostic significance in patients with acute myeloid leukemia. Blood. 2006;107(9):3724-6. PMID: 16368883. PMCID: PMC1895777.
Slovak ML, Gundacker H, Bloomfield CD, Dewald G, Appelbaum FR, Larson RA, Tallman MS, Bennett JM, Stirewalt DL, Meshinchi S, Willman CL, Ravindranath Y, Alonzo TA, Carroll AJ, Raimondi SC, Heerema NA. A retrospective study of 69 patients with t(6;9)(p23;q34) AML emphasizes the need for a prospective, multicenter initiative for rare 'poor prognosis' myeloid malignancies [review]. Leukemia. 2006;20(7):1295-7. PMID: 16628187. doi: 10.1038/sj.leu.2404233.
Tse W, Deeg HJ, Stirewalt DL, Appelbaum FR, Radich J, Gooley T. Increased AF1q gene expression in high-risk myelodysplastic syndrome. Br J Haematol. 2005;128(2):218-20. PMID: 15638856. doi: 10.1111/j.1365-2141.2004.05306x.
Kussick SJ, Stirewalt DL, Yi HS, Sheets KM, Pogosova-Agadjanyan E, Braswell S, Norwood TH, Radich JP, Wood BL. A distinctive nuclear morphology in acute myeloid leukemia is strongly associated with a loss of HLA-DR expression and FLT3 internal tandem duplication. Leukemia. 2004;18(10):1591-8. PMID: 15343344. doi: 10.1038/sj.leu.2403458.
Tse W, Meshinchi S, Alonzo TA, Stirewalt DL, Gerbing RB, Woods WG, Appelbaum FR, Radich JP. Elevated expression of the AF1q gene, an MLL fusion partner, is an independent adverse prognostic factor in pediatric acute myeloid leukemia. Blood. 2004;104(10):3058-63. PMID:15217837.
Stirewalt DL. Fine tuning PU.1 [editorial]. Nat Genetics. 2004;36(6):550-1. PMID: 15167927. doi: 10.1038/nq0604-550.
Stirewalt DL, Meshinchi S, Kussick SJ, Sheets KM, Pogosova-Agadjanyan E, Willman CL, Radich, JP. Novel FLT3 point mutations within exon 14 found in patients with acute myeloid leukemia. Br J Haematol. 2004;124(4):481-4. PMID: 14984498.
Stirewalt DL, Pogosova-Agadjanyan EL, Khalid N, Hare DR, Ladne PA, Sala-Torra O, Zhao LP, Radich JP. Single-stranded linear amplification protocol results in reproducible and reliable microarray data from nanogram amounts of starting RNA. Genomics. 2004;83(2):321-31. PMID: 14706461.
Hughes TP, Kaeda J, Branford S, Rudzki Z, Hochhaus A, Hensley ML, Gathmann I, Bolton AE, van Hoomissen IC, Goldman JM, Radich JP; International Randomized Study of Interferon versus STI571 (IRIS) Study Group (including Stirewalt D). Frequency of major molecular responses to imatinib or interferon alfa plus cytarabine in newly diagnosed chronic myeloid leukemia. N Engl J Med. 2003;349(15):1423-32. PMID: 14534335. doi: 20.2056/NEJMoa030513.
Stirewalt DL, Radich JP. The role of FLT3 in haematopoietic malignancies [review]. Nat Rev Cancer. 2003;3(9):650-65. PMID: 12951584. doi: 10.1038/nrc1169.
Meshinchi S, Stirewalt DL, Alonzo TA, Zhang Q, Sweetser DA, Woods WG, Bernstein ID, Arceci RJ, Radich JP. Activating mutations of RTK/ras signal transduction pathway in pediatric acute myeloid leukemia. Blood. 2003;102(4):1474-9. PMID: 12702504. doi: 10.1182/blood-2003-01-0137.
O'Brien SG, Guilhot F, Larson RA, Gathmann I, Baccarani M, Cervantes F, Cornelissen JJ, Fischer T, Hochhaus A, Hughes T, Lechner K, Nielsen JL, Rousselot P, Reiffers J, Saglio G, Shepherd J, Simonsson B, Gratwohl A, Goldman JM, Kantarjian H, Taylor K, Verhoef G, Bolton AE, Capdeville R, Druker BJ; IRIS Investigators (including Stirewalt D). Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med. 2003;348(11):994-1004. PMID: 12637609. doi: 10.1056/NEJMoa022457.
Stirewalt DL, Guthrie KA, Beppu L, Bryant EM, Doney K, Gooley T, Appelbaum FR, Radich, JP. Predictors of relapse and overall survival in Philadelphia chromosome-positive acute lymphoblastic leukemia after transplantation. Biol Blood Marrow Transplant. 2003;9(3):206-12. PMID: 12652472. doi: 10.1053/bbmt.200350025.
Stirewalt DL, Meshinchi S, Radich JP. Molecular targets in acute myelogenous leukemia [review]. Blood Rev. 2003;17(1):15-23. PMID: 12490207.
Stirewalt DL, Appelbaum FR, Willman CL, Zager RA, Banker DE. Mevastatin can increase toxicity in primary AMLs exposed to standard therapeutic agents, but statin efficacy is not simply associated with ras hotspot mutations or overexpression. Leuk Res. 2003;27(2):133-45. PMID: 12526919.
Stirewalt DL, Willman CL, Radich JP. Quantitative, real-time polymerase chain reactions for FLT3 internal tandem duplications are highly sensitive and specific. Leuk Res. 2001;25(12):1085-8. PMID: 11684280.
Stirewalt DL, Kopecky KJ, Meshinchi S, Appelbaum FR, Slovak ML, Willman CL, Radich JP. FLT3, RAS, and TP53 mutations in elderly patients with acute myeloid leukemia. Blood. 2001;97(11):3589-95. PMID: 11369655.
Meshinchi S, Woods WG, Stirewalt DL, Sweetser DA, Buckley JD, Tjoa TK, Bernstein ID, Radich JP. Prevalence and prognostic significance of FLT3 internal tandem duplication in pediatric acute myeloid leukemia. Blood. 2001;97(1):89-94. PMID: 11133746.
Stirewalt DL, Radich JP. Malignancy: Tumor suppressor gene aberrations in acute myelogenous leukemia [review]. Hematology. 2000;5(1):15-25. PMID: 11399598
Stirewalt DL, Clurman B, Appelbaum FR, Willman CL, Radich, JP. p73 mutations and expression in adult de novo acute myelogenous leukemia. Leukemia. 1999;13(7):985-90. PMID: 10400412.
Elkins C, Carbonetti NH, Varela VA, Stirewalt D, Klapper DG, Sparling PF. Antibodies to N-terminal peptides of gonococcal porin are bactericidal when gonococcal lipopolysaccharide is not sialylated. Mol Microbiol. 1992;6(18):2617-28. PMID: 1280317.