Outcomes

This is a curated list of recent products resulting from BC3 collaborations: abstracts, manuscripts, software, and other outputs that were produced in whole or in part with BC3 consulting and collaboration. If you have abstracts, manuscripts or grants that arise as a result of working with BC3, please share with us, and we'll list them here.

Publications

Levine KM, Uy NF, Gooley TA, Voutsinas J, Tratt M, Eaton KD, Santana-Davila R, Berger AH, Baik CS. Osimertinib retreatment for patients with advanced EGFR-mutated non-small cell lung cancer. Cancer Treat Res Commun. 2025 Oct 25;45:101026. doi: 10.1016/j.ctarc.2025.101026. Epub ahead of print. PMID: 41175446.

Sadowska-Klasa A, Xie H, Zamora D, Waghmare A, Hill JA, Duke ER, Green ML, Oshima MU, Sandmaier BM, Jerome KR, Leisenring WM, Boeckh M. Cytomegalovirus Viral Load Continues to Predict Poor Outcomes in Adults and Children Despite Improved Hematopoietic Cell Transplantation Success. Open Forum Infect Dis. 2025 Sep 26;12(11):ofaf612. doi: 10.1093/ofid/ofaf612. PMID: 41180004; PMCID: PMC12574539.

Lynch RC, Cassaday RD, Smith SD, Cowan AJ, Warren EH, Shadman MS, Till BG, Ujjani CS, Morris K, Rasmussen H, Voutsinas J, Gopal AK. Long-term follow-up of dose-dense brentuximab vedotin, ifosfamide, carboplatin and etoposide in second-line treatment of relapsed/refractory classical Hodgkin lymphoma. Br J Haematol. 2025 Oct;207(4):1599-1603. doi: 10.1111/bjh.70052. Epub 2025 Aug 4. PMID: 41070684.

Cheng GS, Campbell AP, Xie H, Ogimi C, Waghmare A, Kuypers J, Nichols WG, Carpenter P, Corey L, Callais C, Sandmaier BM, Stevens-Ayers T, Jerome KR, Chien JW, Leisenring WM, Englund JA, Boeckh M. Respiratory Virus Infections and Pulmonary Impairment after Allogeneic Hematopoietic Cell Transplantation. J Infect Dis. 2025 Oct 1:jiaf503. doi: 10.1093/infdis/jiaf503. Epub ahead of print. PMID: 41027579.

Ebadi M, Fan X, Schoch G, Gooley T, Rashidi A, Smith SD, Shadman M, Holmberg L, Ujjani C, Poh C, Raghunathan V, Ali N, Vo PT, Manjappa S, Menon M, Di M, Lynch R, Ho C, Till BG, Ermoian R, Gopal AK, Tseng YD. Total Body Irradiation Versus Chemotherapy-Only Conditioning in Autologous Haematopoietic Stem Cell Transplantation for Relapsed/Refractory Large B-cell Lymphoma. Clin Oncol (R Coll Radiol). 2025 Oct 14;48:103959. doi: 10.1016/j.clon.2025.103959. Epub ahead of print. PMID: 41172559.

Ng SK, Flaherty PW, Ancheta M, Tindbaek KA, Sekhon MK, Huang JJ, Portuguese AJ, Albittar A, Kopmar NE, Cowan AJ, Shadman M, Hirayama AV, Till BG, Cassaday RD, Turtle CJ, Liu C, Xie H, Leisenring WM, Gauthier J, Liang EC, Hill JA. Opportunities to Improve Antibiotic Stewardship, and Identification of Blood Biomarkers Associated with Bacteremia Following CAR-T Cell Therapy. Transplant Cell Ther. 2025 Oct;31(10):838.e1-838.e16. doi: 10.1016/j.jtct.2025.07.022. Epub 2025 Jul 31. PMID: 40752589.

Avanessian SC, van den Bijgaart RJE, Chew NW, Supper VM, Tang TT, Zhang Y, Zhao YQ, Abe K, Gauthier J, Barry KC. IL-2/IL-15 signaling induces NK cell production of FLT3LG augmenting anti-PD-1 immunotherapy. Cancer Immunol Res. 2025 Oct 13:10.1158/2326-6066.CIR-24-1259. doi: 10.1158/2326-6066.CIR-24-1259. Epub ahead of print. PMID: 41081432; PMCID: PMC12582536.

Park VY, Hippe DS, Kazerouni AS, Biswas D, Bryant ML, Li I, Javid SH, Kilgore M, Kim J, Kim AG, Scheel JR, Lowry KP, Lam DL, Partridge S, Rahbar H. Multiparametric breast MRI to problem-solve mammographically detected suspicious calcifications. Eur J Radiol. 2025 Oct 11;194:112467. doi: 10.1016/j.ejrad.2025.112467. Epub ahead of print. PMID: 41108951.

Leu J, Narra LR, Gooley T, Cross N, Vuong W, Khan H, Kang J, Yang JT, Grassberger C, Gillespie EF. Evaluating risk factors for skeletal-related events among bone metastases from solid tumors. Radiother Oncol. 2025 Oct;211:111048. doi: 10.1016/j.radonc.2025.111048. Epub 2025 Jul 18. PMID: 40685016.

Salit RB, Fan X, Gooley TA, Halpern AB, Ratsamee N, Marshall A, Scott BL, Deeg HJ. Pre-Hematopoietic Cell Transplantation Ruxolitinib in Transplantation-Eligible Patients with Myelofibrosis: Long-Term Outcomes of a Phase II Prospective Study. Transplant Cell Ther. 2025 Sep 13:S2666-6367(25)01446-0. doi: 10.1016/j.jtct.2025.09.020. Epub ahead of print. PMID: 40953734.

Figueiredo JC, Redwood D, Li L, Donato E, Fort D, Fox EE, Grady WM, Green H, Harrison TA, Haupt C, Hsu L, Hullar MAJ, Huyghe JR, Johnson W, Koehne AL, LaBrie SD, Lakey MA, Lin M, Loroña NC, Maresh GA, Matrana M, Mizrahi JD, Nash SH, Nguyen NT, Paruch JL, Phipps AI, Qu C, Randolph TW, Romo S, Thomas CE, Thomas S, Tiesinga J, Whitlow C, Yeung CCS, Yin H, Zibilich CM, Li CI, Thomas TK, Peters U. The Translational Research Program in Cancer Differences across Populations. Cancer Epidemiol Biomarkers Prev. 2025 Sep 2;34(9):1472-1482. doi: 10.1158/1055-9965.EPI-24-1711. PMID: 40576634; PMCID: PMC12349377.

Hullar MA, Kahsai O, Curtis KR, Navarro SL, Zhang Y, Randolph TW, Levy L, Shojaie A, Kratz M, Neuhouser ML, Lampe PD, Raftery D, Lampe JW. Metabolic plasticity of the gut microbiome in response to diets differing in glycemic load in a randomized, crossover, controlled feeding study. Am J Clin Nutr. 2025 Sep;122(3):780-792. doi: 10.1016/j.ajcnut.2025.06.026. Epub 2025 Jul 5. PMID: 40619005; PMCID: PMC12489384.

Heng AK, Gooley T, Lo SS, Yang JT, Gillespie EF, Halasz LM, Tseng YD. The Impact of Race and Ethnicity on Location and Delivery of Palliative Radiotherapy. Am J Clin Oncol. 2025 Sep 1;48(9):429-434. doi: 10.1097/COC.0000000000001202. PMID: 40226958.

Poh C, Chen X, Voutsinas J, Naresh K, Dizon JJ, Shadman M, Lynch RC, Till BG, Ujjani CS, Di M, Raghunathan V, Warren EH, Smith SD, Wu QV, Cherian S, Gopal AK. Impact of immunophenotype on clinical disease characteristics and outcomes in T-cell prolymphocytic leukaemia. Br J Haematol. 2025 Sep 10. doi: 10.1111/bjh.70113. Epub ahead of print. PMID: 40931545.

Chen YA, Kazerouni AS, Phelps MD, Hippe DS, Youn I, Lee JM, Partridge SC, Rahbar H. Time to Enhancement Measured From Ultrafast Dynamic Contrast-Enhanced MRI for Improved Breast Lesion Diagnosis. J Breast Imaging. 2025 Sep 2;7(4):453-462. doi: 10.1093/jbi/wbae089. PMID: 40104982; PMCID: PMC12403217.

Urgessa F, Jenkins I, Tsegaye A, Nigussie H, Kuru T, Gebremedhin A, Abdela F, Tadesse F, Radich J. MicroRNAs as prognostic and predictive biomarkers among chronic myeloid leukemia patients in Addis Ababa, Ethiopia. Sci Rep. 2025 Aug 29;15(1):31844. doi: 10.1038/s41598-025-17371-w. PMID: 40883483; PMCID: PMC12397308

Zamora D, Xie H, Wong E, Santiano C, Vivas-Jimenez A, Sadowska-Klasa A, Kampouri E, Stevens-Ayers T, Ueda Oshima M, Leisenring WM, Hill JA, Boeckh M. ELISPOT as a predictor of clinically significant cytomegalovirus infection after hematopoietic cell transplantation in letermovir recipients. Bone Marrow Transplant. 2025 Aug;60(8):1137-1145. doi: 10.1038/s41409-025-02611-4. Epub 2025 May 6. PMID: 40328898.

Poh C, Voutsinas JM, Shadman M, Lynch RC, Warren EH, Crimp CA, Till BG, Ujjani CS, Di M, Raghunathan V, Smith SD, Wu QV, Shinohara MM, Gopal AK. Pralatrexate is effective in cytotoxic cutaneous T-cell lymphomas. Blood Adv. 2025 Aug 12;9(15):4037-4042. doi: 10.1182/bloodadvances.2025016680. PMID: 40526835; PMCID: PMC12345251.

Bhatt NS, Voutsinas J, Winters M, Leisenring WM, Ballard S, Jenssen K, Baker KS. Work Status, Absenteeism, Presenteeism, and Quality of Life in Young Adult Cancer Survivors. JAMA Netw Open. 2025 Aug 1;8(8):e2528882. doi: 10.1001/jamanetworkopen.2025.28882. PMID: 40857002; PMCID: PMC12381670.

Moosavi D, Curtis KR, Randolph TW, Kahsai OJ, Ammar H, Lim U, Cheng I, Wilkens LR, Le Marchand L, Lampe JW, Hullar MAJ. Stability and Variability of the Human Fecal Microbiome over 2 Years in the Multiethnic Cohort Study: A Metagenomic Analysis. Cancer Epidemiol Biomarkers Prev. 2025 Aug 1;34(8):1386-1394. doi: 10.1158/1055-9965.EPI-24-1770. PMID: 40402042; PMCID: PMC12247528.

Zhou P, Yeshoua BJ, Konuthula N, Pan CJ, Ferrandino RM, Holte SE, Rizvi Z, Marchiano EM, Futran ND, Barber BR. Association of Oral Health Determinants With Oral Squamous Cell Carcinoma in Never-Smoking Adults. Head Neck. 2025 Jul;47(7):2025-2032. doi: 10.1002/hed.28119. Epub 2025 Feb 28. PMID: 40022306; PMCID: PMC12148706.

Manohar PM, Peterson LM, Jenkins IC, Wu QV, Kurland BF, Novakova-Jiresova A, Muzi M, Chen DL, Specht JM, Dintzis S, Kinahan PE, Mankoff DA, Linden HM. [18 F]-Fluoroestradiol PET (FES-PET) and [18 F] Flurodeoxyglucose PET (FDG-PET) Imaging May Aid in Managing Therapy in Patients with Metastatic Lobular Breast Cancer. Mol Imaging Biol. 2025 Jun;27(3):410-420. doi: 10.1007/s11307-025-02015-2. Epub 2025 May 14. PMID: 40369385; PMCID: PMC12162187.

Moosavi D, Mullens DA, Davidson LA, Fan YY, Goldsby JS, Ivanov IV, Levy L, Kahsai OJ, Curtis KR, Raftery D, Purcell HJ, Mather E, Ammar H, Randolph T, Issaka RB, Navarro SL, Lampe JW, Hullar MA, Chapkin RS. Gut microbial community and host intestinal gene expression with combined fish oil and soluble corn fiber compared with corn oil and maltodextrin: A randomized crossover trial in healthy older individuals. Am J Clin Nutr. 2025 Aug;122(2):396-412. doi: 10.1016/j.ajcnut.2025.04.031. Epub 2025 Jun 19. PMID: 40754387; PMCID: PMC12405781.

Wuliji N, Jones SMW, Gooley T, Gerds AT, Medeiros BC, Shami PJ, Galvin J, Adekola K, Luger S, Baer MR, Rizzieri D, Wildes TM, Wang ES, Sekeres MA, Mukherjee S, Smith J, Garrison M, Kojouri K, Appelbaum J, Percival ME, Sandmaier BM, Lee S, Appelbaum FR, Rouce R, Sorror ML. Social determinants of health and access to allogeneic hematopoietic cell transplantation for acute myeloid leukemia. Blood. 2025 Jun 19;145(25):3041-3051. doi: 10.1182/blood.2024027543. PMID: 40067123.

Ashford NK, Rane S, Farris KM, Miglani J, Chu B, Hippe DS, Gandhi T, Hanson AJ. Acute cerebral blood flow response to heavy cream ingestion in older adults: A non-randomized pilot study. J Alzheimers Dis. 2025 Jul;106(1):331-341. doi: 10.1177/13872877251340369. Epub 2025 May 19. PMID: 40388716.

Mehta RS, Lee SJ, Gooley T, Thur L, Dahlberg A, Delaney C, Gyurkocza B, Vo P, Deeg HJ, Milano F. Long-term outcomes and quality of life with treosulfan-based conditioning in hematological malignancies. Blood Adv. 2025 Jun 10;9(11):2691-2694. doi: 10.1182/bloodadvances.2024015392. PMID: 39969207; PMCID: PMC12159895.

Samples L, Sadrzadeh H, Frigault MJ, Jacobson CA, Hamadani M, Gurumurthi A, Strati P, Shouval R, Noy A, Riedell PA, Dahiya S, Maloney DG, Till BG, Hirayama AV, Gauthier J, Gopal AK, Smith SD, Poh C, Lynch R, Ujjani C, Di M, Raghunathan V, Shakib-Azar M, Naresh KN, Gooley TA, Yared J, Jain MD, Locke FL, Leslie LA, Epperla N, Ghosh M, Skarbnik A, Hill BT, Kamdar MK, Ortiz-Maldonado V, Martinez-Cibrian N, Shune L, Shadman M. Outcomes among adult recipients of CAR T-cell therapy for Burkitt lymphoma. Blood. 2025 Jun 5;145(23):2762-2767. doi: 10.1182/blood.2024026831. PMID: 39938007.

Dahlberg A, Stevenson P, Bhatt NS, Burroughs L, Carpenter PA, Summers C, Tarlock K, Thakar MS, Milano F, Deeg HJ, Bleakley M. Disease Burden at the Time of Transplantation Is a Primary Predictor of Outcomes in Pediatric MDS: A Single-Center Experience. Cancers (Basel). 2025 May 13;17(10):1645. doi: 10.3390/cancers17101645. PMID: 40427141; PMCID: PMC12109966.

Krakow EF, Lee N, Jenkins I, Sala-Torra O, Beppu L, Radich JP, Fukuda B, Sandmaier BM, Yeung CC, Bozic I. A clinical solution for tracking clonal evolution of acute myeloid leukemia after allogeneic transplantation using bulk next generation sequencing. Bone Marrow Transplant. 2025 Aug;60(8):1083-1091. doi: 10.1038/s41409-025-02602-5. Epub 2025 May 16. PMID: 40379905.

Javid SH, Kazerouni AS, Hippe DS, Hirano M, Schnuck-Olapo J, Biswas D, Bryant ML, Li I, Xiao J, Kim AG, Guo A, Dontchos B, Kilgore M, Kim J, Partridge SC, Rahbar H. Preoperative MRI to Predict Upstaging of DCIS to Invasive Cancer at Surgery. Ann Surg Oncol. 2025 May;32(5):3234-3243. doi: 10.1245/s10434-024-16837-x. Epub 2025 Jan 28. Erratum in: Ann Surg Oncol. 2025 May;32(5):3350. doi: 10.1245/s10434-025-17029-x. PMID: 39873851.

Vo P, Ng K, Schoch G, Cooper J, Vupalanchi A, Flowers M, Sandmaier BM, Gooley T, Storb R. Subsequent cancers following non-myeloablative conditioning for allogeneic hematopoietic cell transplantation. Bone Marrow Transplant. 2025 Jul;60(7):1052-1056. doi: 10.1038/s41409-025-02606-1. Epub 2025 Apr 26. PMID: 40287589.

Brumage L, Best S, Hippe DS, Grunblatt E, Chanana P, Wu F, Lee MC, Ying Z, Ibrahim A, Chung JH, Vigil A, Fatherree J, Beronja S, Paddison P, Sullivan L, Nabet B, MacPherson D. In vivo functional screens reveal KEAP1 loss as a driver of chemoresistance in small cell lung cancer. Sci Adv. 2025 Apr 25;11(17):eadq7084. doi: 10.1126/sciadv.adq7084. Epub 2025 Apr 23. PMID: 40267200; PMCID: PMC12017300.

Raychaudhuri S, Gooley TA, Rasmussen A, Quach K, Gill E, Halpern AB, Appelbaum JS, Ghiuzeli CM, Hendrie PC, Cassaday RD, Walter RB, Percival MM. Phase 1 trial of venetoclax with cladribine, cytarabine, G-CSF, and mitoxantrone for AML and high-grade myeloid neoplasm. Blood Neoplasia. 2025 Mar 3;2(3):100085. doi: 10.1016/j.bneo.2025.100085. PMID: 40535475; PMCID: PMC12171542.

Tratt M, Bandhlish A, Eaton KD, Gooley T, Giustini N, Deng L. Survival Outcomes of Lung Adenocarcinoma With Intestinal Differentiation in the Era of Immunotherapy. JTO Clin Res Rep. 2025 Mar 20;6(7):100827. doi: 10.1016/j.jtocrr.2025.100827. PMID: 40534994; PMCID: PMC12172260.

Gong E, Zawacki L, Fan X, Hippe DS, Menon AA, Remington AJ, Lachance K, Akaike T, Tachiki L, Park SY, Nghiem P. Immunotherapy response in immunosuppressed patients with Merkel cell carcinoma: analysis of 183 patients. BMJ Oncol. 2025 Mar 6;4(1):e000654. doi: 10.1136/bmjonc-2024-000654. PMID: 40099002; PMCID: PMC11911694.

Phipps AI, Hill CM, Lin G, Malen RC, Reedy AM, Kahsai O, Ammar H, Curtis K, Ma N, Randolph TW, Ma J, Ogino S, Newcomb PA, Hullar MA. Fusobacterium nucleatum Enrichment in Colorectal Tumor Tissue: Associations With Tumor Characteristics and Survival Outcomes. Gastro Hep Adv. 2025 Feb 20;4(6):100644. doi: 10.1016/j.gastha.2025.100644. PMID: 40487272; PMCID: PMC12138897.

Umoren RA, Ezeaka C, Berkelhamer SK, Hippe DS, Asangansi IE, Cook MW, Fajolu IB, Olawuyi O, Adeboboye C, Ekhalufoh OO, Fashola OS, Feltner J, Fisher JD, James JM, Imoukhuede OM, Park N, Quach V, Stiffler AK, Engmann CM. Essential Newborn Care Virtual Simulations for Skills Retention in Newborn Care. JAMA Netw Open. 2025 Feb 3;8(2):e2460565. doi: 10.1001/jamanetworkopen.2024.60565. PMID: 39976968; PMCID: PMC11843367.

Biswas D, Hippe DS, Winter AM, Li I, Rahbar H, Partridge SC. Diffusion weighted imaging for improving the diagnostic performance of screening breast MRI: impact of apparent diffusion coefficient quantitation methods and cutoffs. Front Oncol. 2024 Dec 20;14:1437506. doi: 10.3389/fonc.2024.1437506. PMID: 39759131; PMCID: PMC11695236.