2024 | 2023 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 - 2007 | IN THE NEWS

2024

Blanco-Melo, D., Campbell, M.A., Zhu, H., Dennis, T.P.W., Modha, S., Lytras, S., Hughes, J., Gatseva, A., Gifford, R.J. (2024). A novel approach to exploring the dark genome and its application to mapping of the vertebrate virus fossil record. Genome Biol. 25(1):120. doi: 10.1186/s13059-024-03258-y.

2023

Yang, Q., Elz, A.E., Panis, M., Liu, T., Nilsson-Payant, B.E., Blanco-Melo, D. (2023). Modulation of Influenza A virus NS1 expression reveals prioritization of host response antagonism at single-cell resolution. Front Microbiol. 14:1267078. DOI: 10.3389/fmicb.2023.1267078

Carrau, L., Frere, J.J., Golynker, I., Fajardo, A., Rivera, C.F., Horiuchi, S., Roonprapunt, T., Minkoff, J.M., Blanco-Melo, D., tenOever, B. (2023). Delayed engagement of host defenses enables SARS-CoV-2 viremia and productive infection of distal organs in the hamster model of COVID-19. Sci Signal. Jun 13;16(789):eadg5470. DOI: 10.1126/scisignal.adg5470

Guzmán-Solís, A.A., Navarro, M.A., Ávila-Arcos, M.C., Blanco-Melo, D. (2023). A Glimpse into the Past: What Ancient Viral Genomes Reveal About Human History. Annu Rev Virol. 10. DOI: 10.1146/annurev-virology-111821-123859

Oishi, K., Blanco-Melo, D., Kurland, A.P., Johnson, J.R., tenOever, B.R. (2023). Archaeal Kink-Turn Binding Protein Mediates Inhibition of Orthomyxovirus Splicing Biology. J Virol. Mar 21:e0181322. DOI: 10.1128/jvi.01813-22

Goodrum, F., Lowen, A., Lakdawala, S., Alwine, J., Casadevall, A., Imperiale, M., Atwood, W., Avgousti, D., Baines, J., Banfield, B., Banks, L., Bhaduri-McIntosh, S., Bhattacharya, D., Blanco-Melo, D., Bloom, D., Boon, A., Boulant, S., Brandt, C., Broadbent, A., Brooke, C., Cameron, C., Campos, S., Caposio, P., Chan, G., Cliffe, A., Coffin, J., Collins, K., Damania, B., Daugherty, M., Debbink, K., DeCaprio, J., Dermody, T., Dikeakos, J., DiMaio, D., Dinglasan, R., Duprex, W.P., Dutch, R., Elde, N., Emerman, M., Enquist, L., Fane, B., Fernandez-Sesma, A., Flenniken, M., Frappier, L., Frieman, M., Frueh, K., Gack, M., Gaglia, M., Gallagher, T., Galloway, D., García-Sastre, A., Geballe, A., Glaunsinger, B., Goff, S., Greninger, A., Hancock, M., Harris, E., Heaton, N., Heise, M., Heldwein, E., Hogue, B., Horner, S., Hutchinson, E., Hyser, J., Jackson, W., Kalejta, R., Kamil, J., Karst, S., Kirchhoff, F., Knipe, D., Kowalik, T., Lagunoff, M., Laimins, L., Langlois, R., Lauring, A., Lee, B., Leib, D., Liu, S.L., Longnecker, R., Lopez, C., Luftig, M., Lund, J., Manicassamy, B., McFadden, G., McIntosh, M., Mehle, A., Miller, W.A., Mohr, I., Moody, C., Moorman, N., Moscona, A., Mounce, B., Munger, J., Münger, K., Murphy, E., Naghavi, M., Nelson, J., Neufeldt, C., Nikolich, J., O'Connor, C., Ono, A., Orenstein, W., Ornelles, D., Ou, J.H., Parker, J., Parrish, C., Pekosz, A., Pellett, P., Pfeiffer, J., Plemper, R., Polyak, S., Purdy, J., Pyeon, D., Quinones-Mateu, M., Renne, R., Rice, C., Schoggins, J., Roller, R., Russell, C., Sandri-Goldin, R., Sapp, M., Schang, L., Schmid, S., Schultz-Cherry, S., Semler, B., Shenk, T., Silvestri, G., Simon, V., Smith, G., Smith, J., Spindler, K., Stanifer, M., Subbarao, K., Sundquist, W., Suthar, M., Sutton, T., Tai, A., Tarakanova, V., tenOever, B., Tibbetts, S., Tompkins, S., Toth, Z., van Doorslaer, K., Vignuzzi, M., Wallace, N., Walsh, D., Weekes, M., Weinberg, J., Weitzman, M., Weller, S., Whelan, S., White, E., Williams, B., Wobus, C., Wong, S., Yurochko, A. (2023). Virology under the Microscope-a Call for Rational Discourse. J Virol. Jan 26:e0008923. mBio. Jan 26:e0018823. mSphere. Jan 26:e0003423. DOI: 10.1128/jvi.00089-23

2021

Nilsson-Payant, B.E., Uhl, S., Grimont, A., Doane, A,S, Cohen, P., Patel, R.S., Higgins, C.A., Acklin, J.A., Bram, Y., Chandar, V., Blanco-Melo, D., Panis, M., Lim, J.K., Elemento, O., Schwartz, R.E., Rosenberg, B.R., Chandwani, R., tenOever, B.R. (2021). The NF-κB Transcriptional Footprint Is Essential for SARS-CoV-2 Replication. J Virol. 95(23):e0125721. DOI: 10.1128/JVI.01257-21

Guzman-Solis, A.A., Villa-Islas, V., Bravo-Lopez, M.J., Sandoval-Velasco, M., Wesp, J.K., Gomez-Valdes, J.A., Moreno-Cabrera, M.L., Meraz, A., SolisPichardo, G., Schaaf, P., tenOever, B. R., Blanco-Melo, D., Avila Arcos, M. C. (2021). Ancient viral genomes reveal introduction of human pathogenic viruses into Mexico during the transatlantic slave trade. Elife 10. DOI: 10.7554/eLife.68612

Si, L., Bai, H., Rodas, M., Cao, W., Oh, C.Y., Jiang, A., Moller, R., Hoagland, D., Oishi, K., Horiuchi, S., Uhl, S., Blanco-Melo, D., Albrecht, R. A., Liu, W. C., Jordan, T., Nilsson-Payant, B. E., Golynker, I., Frere, J., Logue, J., Haupt, R., McGrath, M., Weston, S., Zhang, T., Plebani, R., Soong, M., Nurani, A., Kim, S. M., Zhu, D. Y., Benam, K. H., Goyal, G., Gilpin, S. E., Prantil-Baun, R., Gygi, S. P., Powers, R. K., Carlson, K. E., Frieman, M., tenOever, B. R., Ingber, D. E. (2021). A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics. Nat Biomed Eng 5, 815-829. DOI: 10.1038/s41551-021-00718-9

Hoagland, D.A., Moller, R., Uhl, S.A., Oishi, K., Frere, J., Golynker, I., Horiuchi, S., Panis, M., Blanco-Melo, D., Sachs, D., Arkun, K., Lim, J. K., tenOever, B. R. (2021). Leveraging the antiviral type I interferon system as a first line of defense against SARS-CoV-2 pathogenicity. Immunity 54, 557-570 e555. DOI: 10.1016/j.immuni.2021.01.017

Nilsson-Payant, B.E., Blanco-Melo, D., Uhl, S., Escudero-Perez, B., Olschewski, S., Thibault, P., Panis, M., Rosenthal, M., Munoz-Fontela, C., Lee, B., tenOever, B. R. (2021). Reduced Nucleoprotein Availability Impairs Negative-Sense RNA Virus Replication and Promotes Host Recognition. J Virol 95. DOI: 10.1128/JVI.02274-20

2020

Blanco-Melo, D., Nilsson-Payant, B.E., Liu, W.C., Uhl, S., Hoagland, D., Moller, R., Jordan, T.X., Oishi, K., Panis, M., Sachs, D., Wang, T. T., Schwartz, R. E., Lim, J. K., Albrecht, R. A., tenOever, B. R. (2020). Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19. Cell 181, 1036-1045 e1039. DOI: 10.1016/j.cell.2020.04.026

2019

Munoz-Moreno, R., Martinez-Romero, C., Blanco-Melo, D., Forst, C.V., Nachbagauer, R., Benitez, A.A., Mena, I., Aslam, S., Balasubramaniam, V., Lee, I., Panis, M., Ayllon, J., Sachs, D., Park, M. S., Krammer, F., tenOever, B. R., Garcia-Sastre, A. (2019). Viral Fitness Landscapes in Diverse Host Species Reveal Multiple Evolutionary Lines for the NS1 Gene of Influenza A Viruses. Cell Rep 29, 3997-4009 e3995. DOI: 10.1016/j.celrep.2019.11.070

Eggenberger, J., Blanco-Melo, D., Panis, M., Brennand, K.J., and tenOever, B.R. (2019). Type I interferon response impairs differentiation potential of pluripotent stem cells. Proc Natl Acad Sci U S A 116, 1384-1393. DOI: 10.1073/pnas.1812449116

2018

Aguado, L.C., Jordan, T.X., Hsieh, E., Blanco-Melo, D., Heard, J., Panis, M., Vignuzzi, M., and tenOever, B.R. (2018). Homologous recombination is an intrinsic defense against antiviral RNA interference. Proc Natl Acad Sci U S A 115, E9211-E9219. DOI: 10.1073/pnas.1810229115

Blanco-Melo, D., Gifford, R.J., and Bieniasz, P.D. (2018). Reconstruction of a replication-competent ancestral murine endogenous retrovirus-L. Retrovirology 15, 34. DOI: 10.1186/s12977-018-0416-3

Takata, M.A., Soll, S.J., Emery, A., Blanco-Melo, D., Swanstrom, R., and Bieniasz, P.D. (2018). Global synonymous mutagenesis identifies cis-acting RNA elements that regulate HIV-1 splicing and replication. PLoS Pathog 14, e1006824. DOI: 10.1371/journal.ppat.1006824

2017

Takata, M.A., Goncalves-Carneiro, D., Zang, T.M., Soll, S.J., York, A., Blanco-Melo, D., and Bieniasz, P.D. (2017). CG dinucleotide suppression enables antiviral defence targeting non-self RNA. Nature 550, 124-127. DOI: 10.1038/nature24039

Aguado, L.C., Schmid, S., May, J., Sabin, L.R., Panis, M., Blanco-Melo, D., Shim, J.V., Sachs, D., Cherry, S., Simon, A.E., Levraud, J. P., tenOever, B. R. (2017). RNase III nucleases from diverse kingdoms serve as antiviral effectors. Nature 547, 114-117. DOI: 10.1038/nature22990

Blanco-Melo, D., Gifford, R.J., and Bieniasz, P.D. (2017). Co-option of an endogenous retrovirus envelope for host defense in hominid ancestors. Elife 6. DOI: 10.7554/eLife.22519

2016-2007

Blanco-Melo, D., Venkatesh, S., and Bieniasz, P.D. (2016). Origins and Evolution of tetherin, an Orphan Antiviral Gene. Cell Host Microbe 20, 189-201. DOI: 10.1016/j.chom.2016.06.007

Magiorkinis, G., Blanco-Melo, D., and Belshaw, R. (2015). The decline of human endogenous retroviruses: extinction and survival. Retrovirology 12, 8. DOI: 10.1186/s12977-015-0136-x

Kutluay, S.B., Zang, T., Blanco-Melo, D., Powell, C., Jannain, D., Errando, M., and Bieniasz, P.D. (2014). Global changes in the RNA binding specificity of HIV-1 gag regulate virion genesis. Cell 159, 1096-1109. DOI: 10.1016/j.cell.2014.09.057

Busnadiego, I., Kane, M., Rihn, S.J., Preugschas, H.F., Hughes, J., Blanco-Melo, D., Strouvelle, V.P., Zang, T.M., Willett, B.J., Boutell, C., Bieniasz, P. D., Wilson, S. J. (2014). Host and viral determinants of Mx2 antiretroviral activity. J Virol 88, 7738-7752. DOI: 10.1128/JVI.00214-14

Blanco-Melo, D., Venkatesh, S., and Bieniasz, P.D. (2012). Intrinsic cellular defenses against human immunodeficiency viruses. Immunity 37, 399-411. DOI: 10.1016/j.immuni.2012.08.013

Arenas-Huertero, C., Perez, B., Rabanal, F., Blanco-Melo, D., De la Rosa, C., Estrada-Navarrete, G., Sanchez, F., Covarrubias, A.A., and Reyes, J.L. (2009). Conserved and novel miRNAs in the legume Phaseolus vulgaris in response to stress. Plant Mol Biol 70, 385-401. DOI: 10.1007/s11103-009-9480-3

Flores, M., Morales, L., Gonzaga-Jauregui, C., Dominguez-Vidana, R., Zepeda, C., Yanez, O., Gutierrez, M., Lemus, T., Valle, D., Avila, M.C., Blanco, D., Medina-Ruiz, S., Meza, K., Ayala, E., Garcia, D., Bustos, P., Gonzalez, V., Girard, L., Tusie-Luna, T., Davila, G., Palacios, R. (2007). Recurrent DNA inversion rearrangements in the human genome. Proc Natl Acad Sci U S A 104, 6099-6106. DOI: 10.1073/pnas.0701631104

IN THE NEWS

Evolutionary virologist Daniel Blanco-Melo seeks out ancient pathogens by Pratik Pawar. Science News (2023) – Profile for SN10: Scientists to Watch.

The Fatal Error of an Ancient, HIV-Like Virus by Katherine J. Wu. The Atlantic (2022) – Interview on primate endogenous lentiviruses.

Ancient tooth DNA reveals how ‘cold sore’ herpes virus has evolved by Freda Kreier. Nature News (Nature 609, 21-22) – Interview on ancient Herpesviruses.

Todo lo que siempre quisiste saber sobre la vacuna contra el COVID-19. Migala Podcast (2020) – Live YouTube interview on COVID-19 and available vaccines. En español.

Scientists Unearth Ancient DNA Depicting a Battle Between Viruses and Our Ancestors By Ryan F. Mandelbaum. Gizmodo.com (2017) - Interview on co-option of endogenous retroviruses.

El fósil de un virus narra cómo nuestros ancestros lo extinguieron by Agustín Ávila-Casanueva. Tenga para que se entretenga Science Blog (2017) – Interview on co-option of endogenous retroviruses. En español.