Publications


2026

Garcia MA, Farrell-Sherman A, Zhuo J, Fray E, Zinsser AM, Aydin B, Sowers K, Lai J, Li H, Lopez BM, Abeyta-Lopez A, Chu T, Lubbeck D, Chae M, Varriale J, Westfall DH, Hoh R, Dalhuisen T, Simonetti FR, Peluso MJ, Deeks SG, Siliciano RF, Cohn LB, Siliciano JD. (2026) Inhibitory potential of autologous neutralizing antibodies sets quantitative limits on the rebound-competent HIV-1 reservoir. PNAS [In Press]. [original work]

Romero EV, Clyde AE, Giorgi EE, Westfall DH, Azam W, Taylor ML, Caskey M, Feder AF, Cohn LB. (2026) Recurrent mutations drive rapid HIV escape from two broadly neutralizing antibodies in vivo. Proc Natl Acad Sci U S A. 123(16):e2524021123. doi: 10.1073/pnas. 2524021123. PMID: 41980093; PMCID: PMC13099683. [original work]


2025

Peluso MJ, Sandel DA, Deitchman AN, Kim SJ, Dalhuisen T, Tummala HP, Tibúrcio R, Zemelko L, Borgo GM, Singh SS, Schwartz K, Deswal M, Williams MC, Hoh R, Shimoda M, Narpala S, Serebryannyy L, Khalili M, Vendrame E, SenGupta D, Whitmore LS, Tisoncik-Go J, Gale M Jr, Koup RA, Mullins JI, Felber BK, Pavlakis GN, Reeves JD, Petropoulos CJ, Glidden DV, Spitzer MH, Gama L, Caskey M, Nussenzweig MC, Chew KW, Henrich TJ, Yukl SA, Cohn LB, Deeks SG, Rutishauser RL. (2025) Correlates of HIV-1 control after combination immunotherapy. Nature. doi: 10.1038/s41586-025-09929-5. PMID: 41326736. [original work]

Romero EV, Clyde AE, Giorgi EE, Westfall DH, Azam W, Taylor ML, Caskey M, Feder AF, Cohn LB. (2025) Distinct modes of evolution drive HIV escape from two broadly neutralizing antibodies. bioRxiv. doi: 10.1101/2025.08.29.673185. PMCID: PMC12407991. [original work]

Nguyen E, Korolkova A, Ahmed A, Meanley S, Dee L, Hussain M, Wan F, Hoh R, Rodriguez A, Figueroa T, Cohn LB, Deeks SG, Peluso MJ, Eskaf S, Sugarman J, Sauceda JA, Dubé K. (2025) Participant Perspectives in an HIV Treatment Interruption Study in San Francisco, United States. AIDS Res Hum Retroviruses. 41(11):505-16. doi: 10.1177/08892229251375470. PMCID: PMC12448951. [original work]

Farrell-Sherman A, de la Force N, Prator CA, Valieris R, Azam W, Da Silva I, Deeks SG, Thanh C, Bosch RJ, Henrich TJ, Cohn LB. (2025) Antiviral Monocytes Increase Prior to Detectable HIV-1 Rebound Viremia. Journal of Infectious Diseases. 232(5):1061-66. doi: 10.1093/infdis/jiaf367. PMCID: PMC12614978. [original work]

Reeves DB, Litchford M, Fish CS, Farrell-Sherman A, Poindexter M, Ahmed N, Cassidy NAJ, Neary J, Wamalwa D, Langat A, Chebet D, Moraa H, Antar AAR, Slyker J, Benki-Nugent S, Cohn LB, Schiffer JT, Overbaugh J, John-Stewart G, Lehman DA. (2025) Intact HIV DNA decays in children with and without complete viral load suppression. PLoS Pathogens. 21(4):e1013003. doi: 10.1371/ journal.ppat. 1013003. PMCID: PMC12002518. [original work]

Meanley S, Rodriguez Garcia L, Lisha NE, Ahmed A, Korolkova A, Figueroa T, Nguyen E, J Peluso M, Cohn LB, Deeks S, Dubé K, Sauceda J. (2025) Exploring Stigma and Self-Image: Mixed-Methods Insights from HIV Cure-Related Research Participants Undergoing Analytical Treatment Interruptions. AIDS Patient Care STDS. 39(4):151-59.  doi: 10.1089/apc.2024.0254. PMCID: PMC12139701. [original work]

Hill M, Garcia LR, Nguyen E, Korolkova A, Cohn LB, Rodriguez A, Hoh R, Deeks SG, Peluso MJ, Sauceda JA, Dubé K. (2025) Evaluating the psychosocial experiences of participants in HIV cure research before, during, and after analytical treatment interruptions: A longitudinal qualitative study in the United States. Soc Sci Med. 366:117644. doi: 10.1016/j.socscimed.2024.117644. PMID: 39754855; PMCID: PMC11915557. [original work]

Serrano-Villar S, Gala A, Bacchetti P, Hoh R, di Germanio C, Cohn LB, Henrich TJ, Hunt PW, Laird GM, Pillai SK, Deeks SG, Peluso MJ. (2025) Galectin 9 Levels as a Potential Predictor of Intact HIV Reservoir Decay. Journal of Infectious Diseases. 231(1):156-64. doi: 10.1093/infdis/jiae426. PMCID: PMC11793034. [original work]


2023

Reeves DB, Gaebler C, Oliveira TY, Peluso MJ, Schiffer JT, Cohn LB, Deeks SG, Nussenzweig MC. (2023) Impact of misclassified defective proviruses on HIV reservoir measurements. Nat. Comm. 14(1):4186. doi: 10.1038/s41467-023-39837-z. PMCID: PMC10345136. [original work]

Henrich T, Peluso M, Cohn LB, Flavell R, Dletchman A, Koch W, Aslam M, Asare K, Castillo J, Krishnan H, Munter S, Ryder D, Hoh R, Deeks S, VanBrocklin H. (2023) ImmunoPET Imaging of Tissue HIV-1 Activity in People with HIV Participating in an Antiretroviral Therapy Interruption Study. Journal of Nuclear Medicine. 6(1):1158. [original work]


2022

Weymar GHJ, Bar-On Y, Oliveira TY, Gaebler C, Ramos V, Hartweger H, Breton G, Caskey M, Cohn LB, Jankovic M, Nussenzweig MC. (2022) Distinct gene expression by expanded clones of quiescent memory CD4+ T cells harboring intact latent HIV-1 proviruses. Cell Rep. 40(10):111311. doi: 10.1016/j.celrep.2022.111311. PMCID: PMC9471989. [original work]


2021

Huang AS, Ramos V, Oliveira TY, Gaebler C, Jankovic M, Nussenzweig MC, Cohn LB. (2021) Integration features of intact latent HIV-1 in CD4+ T cells clones contribute to viral persistence. J Exp Med 218(12):e20211427. doi: 10.1084/jem.20211427. PMCID: PMC8515646. [original work]


Prior to 2021

Crawford ED et al. (2020) Rapid deployment of SARS-CoV-2 testing: the CLIAHUBPLoS Pathog.16(10):e1008966. doi: 10.1371/journal.ppat.1008966. PMCID: PMC7592773. [original work]

Cohn LB, Deeks SG. (2020) The immune response fails to control HIV early in initial virus spreadJ Clin Invest. 130(6):2803-5. doi: 10.1172/JCI136886. PMCID: PMC7259984. [editorial]

Cohn LB, Chomont N, Deeks SG. (2020) The biology of the HIV-1 latent reservoir and implications for cure strategiesCell Host and Microbe. 27(4):519-30. doi: 10.1016/j.chom.2020.03.014. PMCID: PMC7219958. [invited review]

Mendoza P, Jackson JR, Oliveira T, Gaebler C, Ramos V, Caskey M, Jankovic M, Nussenzweig MC, Cohn LB. (2020) Antigen responsive CD4+ T cell clones contribute to the HIV-1 latent reservoirJ Exp Med. 217(7): e20200051. doi: 10.1084/jem.20200051. PMCID: PMC7336300. [original work]

Bruner KM, Cohn LB. (2019) HIV-1 reservoir dynamics in CD4+ T cellsCurr Opin HIV AIDS. 14(2):108-14. doi: 10.1097/COH. 0000000000000521. PMCID: PMID: 30531293. [invited review]

Lu CL, Pai JA, Nogueira L, Mendoza P, Gruell H, Oliveira TY, Barton J, Lorenzi JCC, Cohen YZ, Cohn LB, Klein F, Caskey M, Nussenzweig MC, Jankovic M. (2018) Relationship between intact HIV-1 proviruses in circulating CD4+ T cells and rebound viruses emerging during treatment interruptionProc Natl Acad Sci USA. 115(48):E11341-48. doi: 10.1073/pnas.1813512115. PMCID: PMC6275529. [original work]

Battivelli E, Dahabieh M, Abdel-Mohsen M, Svensson JP, Silva IT, Cohn LB, Gramatica A, Deeks S, Greene W, Pillai S, and Verdin E. (2018) Distinct Chromatin Functional States Correlate with HIV Latency Reactivation in Infected Primary CD4+ T CellseLife. 7e34655. doi:10.7554/eLife.34655. PMCID: PMC5973828. [original work]

Cohn LB, da Silva IT, Valieris R, Huang AS, Lorenzi JCC, Cohen YZ, Pai JA, Butler AL, Caskey M, Jankovic M, Nussenzweig MC. (2018) Clonally expanded CD4+ T cells contribute to the HIV-1 latent reservoir and display a distinct gene profile upon reactivationNat Med. 24(5):604-9. doi: 10.1038/s41591-018-0017-7. PMCID: PMC5972543. [original work]

Cohn LB and Nussenzweig MC. (2017) HIV: Persistence through DivisionJ Exp Med. 214(4):875-76. doi: 10.1084/jem.20170463. PMCID: PMC5379988. [editorial]

Lorenzi JC, Cohen YZ, Cohn LB, Kreider EF, Barton JP, Learn GH, Oliveira T, Lavine CL, Horwitz JA, Settler A, Jankovic M, Seaman MS, Chakraborty AK, Hahn BH, Caskey M, Nussenzweig MC. (2016) Paired quantitative and qualitative assessment of the replication-competent HIV-1 reservoir and comparison with integrated proviral DNAProc Natl Acad Sci. USA 113(49):E7908-16. doi: 10.1073/pnas.1617789113. PMCID: PMC5150408. [original work]

Reis BS, Lee K, Fanok MH, Mascaraque C, Amoury M, Cohn LB, Rogoz A, Dallner OS, Moraes-Vieira PM, Domingos AI, Mucida D. (2015) Leptin Receptor Signaling in T Cells is Required for Th17 DifferentiationJ Immunol. 194(11):5253-60. doi: 10.4049/jimmunol.1402996. PMCID: PMC4433844. [original work]

Cohn LB, Silva IT, Oliveira TY, Rosales RA, Parrish EH, Learn GH, Hahn BH, Czartoski JL, McElrath MJ, Lehmann C, Klein F, Caskey M, Walker BD, Siliciano JD, Siliciano RF, Jankovic M, Nussenzweig MC. (2015) HIV-1 integration landscape in active and latent infectionCell. 160(3):420-32. doi: 10.1016/j.cell.2015.01.020. PMCID: PMC4371550. [original work]

Cohn L, Delamarre L. (2014) Dendritic Cell Targeted VaccinesFront in Immunol. 5:255 (1-11). doi: 10.3389/fimmu.2014.00255. PMCID: PMC4039009. [invited review]

Cohn L, Chatterjee, B, Esselborn, F, Smed-Sörensen A, Nakamura N, Chalouni C, Lee BC, Vandlen R, Keler T, Lauer P, Brockstedt D, Mellman I, Delamarre L. (2013) Antigen delivery to early endosomes eliminates the superiority of human blood BDCA3 dendritic cells at cross presentationJ Exp Med. 210(5):1049-63. doi: 10.1084/jem.20121251. PMCID: PMC3646496. [original work]

Chatterjee, B, Smed-Sörensen A, Cohn L, Chalouni C, Vandlen R, Lee BC, Widger J, Keler T, Delamarre L, Mellman I. (2012) Internalization and endosomal degradation of receptor-bound antigens regulate the efficiency of cross presentation by human dendritic cells. Blood. 120(10): 2011-20. doi: 10.107782/blood-2012-01-402370. PMID: 22791285. [original work]

Smed-Sörensen A, Chalouni C, Chatterjee, B, Cohn L, Blattmann P, Nakamura N, Delamarre L, Mellman I. (2012) Influenza A virus infection of human primary dendritic cells impairs their ability to cross-present antigen to CD8 T cells. PLoS Pathog. 8(3):e1002572. doi:10.1371/journal.ppat. 1002572. PMCID: PMC3297599. [original work]

Breton G, Yassine-Diab B, Cohn L, Boulassel MR, Routy JP, Sékaly RP, Steinman RM. (2009) siRNA knockdown of PD-L1 and PD-L2 in monocyte-derived dendritic cells only modestly improves proliferative responses to Gag by CD8(+) T cells from HIV-1-infected individuals. J Clin Immunol. 29(5):637-45. doi: 10.1007/s10875-009-9313-9. PMID: 19562472; PMCID: PMC2933267. [original work]