Signaling Networks as Targets for Drug Discovery

In the Gujral lab, we believe that a deeper understanding of cell-cell communication is the key to a better understanding of human health and disease. We are motivated to translate this newly acquired knowledge into innovative targeted therapies and impact the lives of patients and their families. Members of the Gujral lab fight biological complexity with ingenuity and interdisciplinarity. We integrate state-of-the-art methods from several fields, including advanced computer science, pharmacology, and cell biology, to investigate tissue-specific signaling networks, identify the most promising molecular targets for drug discovery, and new uses for existing medicines. We are also working as members of the broader community that aims to revolutionize drug discovery by changing its focus from target-centric to network-centric.