The Kiem Lab studies cell and gene therapy with a particular interest in the biology of blood and marrow stem cells and the development and use of novel gene therapy and genome editing technologies for ex vivo and in vivo applications. The overall goal is to develop better stem cell transplantation and cell and gene therapy treatments for patients with genetic, infectious, and malignant diseases.
Research topics in the lab include:
The Kiem Lab is also part of multiple collaborations to improve the efficiency by which HSCs can be cultured and transduced, while closely monitoring the gene-modified clones through cutting-edge high-throughput retroviral integration site analysis.
We are located in the Thomas Building of Fred Hutchinson Cancer Research Center, rooms D1-270, D1-271, D1-275 and D1-295.
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The vector core assists investigators with design, construction and/or production of viral vectors. We are offering reasonable service fees compared to industry standard prices with an extra 75% discount for all members of the Fred Hutch and affiliated academic groups. We have a turnaround time of approximately two to three weeks between receiving the transfer plasmid and final product release.
We are located in the Thomas Building of Fred Hutchinson Cancer Research Center, Fred Hutch Vector Core, D1-324
Ready-to-use vector aliquots for immediate pick-up
Gammaretroviral, lentiviral, and foamyviral, Vector production
Adeno-associated viral vector (AAV) production
Clinical Grade Vector Production