Join our Lab

Abby Wall works in the McGuire Lab
Abby Wall working in the McGuire Lab Credit: Fred Hutch

The McGuire lab in the Vaccine and Infectious Disease Division of Fred Hutch seeks enthusiastic, organized, and independent graduate students and post-doctoral research fellows who are interested in developing immunology, biochemistry or vaccinology skills.

Staff Scientist

We are seeking a Staff Scientist to assist with the development, validation, and testing of novel vaccine candidates aimed at preventing infection by viruses of global health importance including HIV-1, Epstein-Barr virus, or Respiratory Syncytial virus. The candidate will perform an in-depth characterization of the B cell and antibody response to novel candidate vaccines, conduct vaccine-challenge studies, perform data analysis, prepare reports/manuscripts, and supervise lab staff and related activities.

Post Doctoral Scientist

We are seeking a Post-Doctoral Scientist to assist with the development, validation, and testing of novel HIV-1 vaccine candidates based on anti-idiotypic antibodies (ai-mAbs). The project will build upon our previous efforts to elicit broadly using this approach. The candidate will conduct vaccine studies in various types of humanized mice and  perform an in-depth characterization of the B cell and serum antibody response to novel ai-mAbs using high-throughput next generation sequencing,

Research Technician II

  • Conducting diagnostic qPCR and ddPCR assays to quantify viral loads in blood and tissue
  • Recovery and cloning of antibody transcripts from single cells using RT-PCR
  • Handling of mice including breeding, immunizations, and bleeds
  • Cell culture of mammalian cell lines
  • Collect and analyze data and maintain experimental records
  • Perform statistical analysis of test results and prepare written reports on work performed.
  • Operate and carry out basic maintenance of laboratory equipment.
  • Perform other duties as required

Graduate Students interested in joining the lab should reach out to Dr. McGuire directly

Apply online at Fred Hutch's careers website.