Publications

Dr. Andy McGuire looks in the microscope while doing lab work
Dr. Andy McGuire looks in the microscope while doing lab work Fred Hutch

Complete Bibliography

Visit PubMed to view Dr. Andy McGuire's complete publication record.


Selected Publications

mRNA vaccination boosts cross-variant neutralizing antibodies elicited by SARS-CoV-2 infection Stamatatos L, Czartoski J, Wan Y-H, Homad LJ,  Rubin V,  Glantz H, Neradilek M, Seydoux E, Jennewein MF, MacCamy AJ, Feng J, Mize G, De Rosa SC, Finzi A, Lemos M, Cohen KW, Moodie Z, McElrath MJ and McGuire AT. Science. 2021, (372) 6549, pp. 1413-1418

Structural basis for broad coronavirus neutralization. Sauer MM, Tortorici MA, Park YJ, Walls AC, Homad L, Acton OJ, Bowen JE, Wang C, Xiong X, de van der Schueren W, Quispe J, Hoffstrom BG, Bosch BJ, McGuire AT and Veesler D. Nat Struct Mol Biol. 2021 Jun;28(6):478-486

Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies  Seydoux E, Wan  Y-H,  Feng J, Wall A, Aljedani S,Homad LJ,  MacCamy, AJ,  Weidle C, Gray MD,  Brumage L, Taylor J, Pancera M, Stamatatos L, and McGuire AT.  Cell Reports. 2021 2021 May 4;35(5):109084

Neutralizing Antibodies Protect against Oral Transmission of Lymphocryptovirus Singh S, Homad LJ, Akins NR, Stoffers CM, Lackhar S, Malhi H, Wan Y-H, Rawlings DJ, and McGuire AT. Cell Reports Medicine. 2020 1(3),100033 

Analysis of a SARS-CoV-2-Infected Individual Reveals Development of Potent Neutralizing Antibodies with Limited Somatic Mutation Seydoux S,  Homad LJ,  MacCamy AJ,  Parks KR, , Hurlburt NK, Jennewein MF,  Akins NR, Stuart AB, Wan Y-H, Feng J, Whaley RE, Singh S, Boeckh M, Cohen KW, McElrath MJ, Englund JA, Chu HY, Pancera M, McGuire AT and Stamatatos, L. Immunity. Immunity. 2020 Jul 14;53(1):98-105.e5

Anti-idiotypic antibodies elicit anti-HIV-1-specific B cell responses. Dosenovic P, Pettersson AK, Wall A, Thientosapol ES, Feng J, Weidle C, Bhullar K, Kara EE, Hartweger H, Pai JA, Gray MD, Parks KR, Taylor JJ, Pancera M, Stamatatos L, Nussenzweig MC, McGuire AT. J Exp Med. 2019 Jul 25. pii: jem.20190446. doi: 10.1084/jem.20190446. PMID: 31345931

Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes. Bancroft T, DeBuysscher BL, Weidle C, Schwartz A, Wall A, Gray MD, Feng J, Steach HR, Fitzpatrick KS, Gewe MM, Skog PD, Doyle-Cooper C, Ota T, Strong RK, Nemazee D, Pancera M, Stamatatos L, McGuire AT, Taylor JJ. J Exp Med. 2019 Jul 25. pii: jem.20190164. doi: 10.1084/jem.20190164. PMID: 31345930

An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus. Snijder J, Ortego MS, Weidle C, Stuart AB, Gray MD, McElrath MJ, Pancera M, Veesler D, McGuire AT. Immunity. 2018 Apr 17;48(4):799-811.e9. doi: 10.1016/j.immuni.2018.03.026. PMID: 29669253

Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice. McGuire AT, Gray MD, Dosenovic P, Gitlin AD, Freund NT, Petersen J, Correnti C, Johnsen W, Kegel R, Stuart AB, Glenn J, Seaman MS, Schief WR, Strong RK, Nussenzweig MC, Stamatatos L. Nat Commun. 2016 Feb 24;7:10618. doi: 10.1038/ncomms10618. PMID: 26907590

HIV antibodies. Antigen modification regulates competition of broad and narrow neutralizing HIV antibodies. McGuire AT, Dreyer AM, Carbonetti S, Lippy A, Glenn J, Scheid JF, Mouquet H, Stamatatos L. Science. 2014 Dec 12;346(6215):1380-1383. doi: 10.1126/science.1259206. PMID: 25504724

Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies. McGuire AT, Hoot S, Dreyer AM, Lippy A, Stuart A, Cohen KW, Jardine J, Menis S, Scheid JF, West AP, Schief WR, Stamatatos L. J Exp Med. 2013 Apr 8;210(4):655-63. doi: 10.1084/jem.20122824. Epub 2013 Mar 25. PMID: 23530120