Parkhurst Lab

 

Our Research

A hallmark of many diseases and cancers is a dysfunctional cytoskeleton. A properly functioning cytoskeleton is needed for a wide variety of cellular events ranging from cell shape to cell signaling and migration/metastasis. We use multidisciplinary approaches to study these dynamic structural elements in various processes including wound repair and nuclear architecture/organization. The goal of the Parkhurst Lab is to understand the role of these elements in regulating normal developmental events and how this regulation goes awry in diseases/cancers, thereby providing new avenues for possible therapeutic targets or to enhance the effectiveness of existing treatment modalities.

Learn More About Our Research
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Research Projects

Wound healing

Cell Wound Repair

Molecular and cellular mechanisms of single cell wound repair.

Mechano Landing

Mechanoregulation

How cells sense and respond to mechanical signals and/or stresses.

NEB Landing

Nuclear Envelope Budding

Molecular machineries and mechanisms underlying the phiysical aspects of NE-Budding.

Labs & Resources

Parkhurst in lab

Lab Members

Current lab members and lab alumni.

Books

Publications

Publications from or with the Parkhurst Lab and our lab's journal/book covers.

Glassware

Reagents

Information on resources generated by the Parkhurst Lab.