Publications

2019

Fries CA, Lawson SD, Wang LC, Spencer JR, Roth M, Rickard RF, Goranthla VS, Davis MR. Composite Graft Pretreatment with Hydrogen Sulfide Delays the Onset of Acute Rejection. Annals of Plastic Surgery, 2019. January. PMID: 30628928.

2018

Morrison ML, Iwata A, Keys C, Langston W, Insko MA, Langdale LA, and Roth M. Iodide Improves Outcome After Acute Myocardial Infarction in Rates and Pigs. Critical Care Med 2018. November, 46(11)e1063-e1069, PMID: 30063489.

2017

Black GE, Sokon KK, Moe DM, Simmons J, Muscat D, Pastukh V, Capley G, Gorodnya O, Rucko M, Roth M, Gillespie M, Martin MJ. (2017) Impact of a Novel P13-KINASE Inhibitor in Preventing Mitochondrial DNA Damage and Associated Molecular Pattern Accumulation: Results from the Biochronicity Project. J Trauma Acute Care Surg. 83(4):683-689

2016

Black GE, Sokol KK, Shawhan RR, Eckert MJ, Salgar S, Marko ST, Hoffer ZS, Keyes CC, Roth MB, Martin MJ. (2016) Inducing metabolic suppression in severe hemorrhagic shock: Pilot study results from the Biochronicity Project. J Trauma Acute Care Surg. Dec; 81(6):1003-1011.

2015

Iwata, A., Morrison, M.L., Blackwood, J.E., and Roth, M.B. (2015) Selenide Targets to Reperfusing Tissue and Protects It from Injury. Crit Care Med, 43(7):1361-7. PMCID: 25853592.

LaMacchia JC, Roth MB. (2015) Aquaporins-2 and -4 regulate glycogen metabolism and survival during hyposmotic-anoxic stress in Caenorhabditis elegans. Am J Physiol. Cell Physiol. 309(2):C92-6. PMCID: 26017147.

LaMacchia JC, Frazier HN 3rd, Roth MB. (2015) Glycogen Fuels Survival During Hyposmotic-Anoxic Stress in Caenorhabditis elegans. Genetics. 201(1):65-74. PMCID: 26116152.

Iwata A, Morrison ML, Roth M. Correction: (2015) Iodide Protects Heart Tissue from Reperfusion Injury. PLoS One. 10(9):e0138396.

2014

Iwata, A., Morrison, M.L., Fries, C.A., Davis, M.R., and Roth M.B. (2014) Iodide Protects Heart Tissue from Reperfusion Injury. PLoS One 9(11): e112458. PMCID: PMC4224479
Villamaria, C.Y., Spencer, J.R., Fries, C.A., Davis, M.R., and Roth M. (2014) Hydrogen Sulfide Mitigates Reperfusion Injury in a Porcine Model of Vascularized Composite Autotransplantation. Ann Plast Surg 72(5): 594-8.

2011

Budde, M.W., and Roth, M (2011) The Response of Caenorhabditis elegans to Hydrogen Sulfide and Hydrogen Cyanide. Genetics 189(2):521-32. PMCID: PMC3189795.

Miller, D.L., Budde, M.W., and Roth, M (2011) HIF-1 and SKN-1 Coordinate the Transcriptional Response to Hydrogen Sulfide in Caenorhabditis elegans. PLoS One 6(9):e25476. PMCID: PMC3183046

2010

Chan, K., Goldmark, J.P., and Roth M. (2010) Suspended Animation Extends Survival Limits of Caenorhabditis elegans and Saccharomyces cerevisiae at Low Temperature. Mol Biol Cell (13):2161-71. PMCID: PMC2893981.

Budde, M.W. and Roth M. (2010) Hydrogen Sulfide Increases HIF-1 Activity Independent of VHL-1 in C. elegans. Mol Biol Cell. 21(1):212-7. PMCID: PMC2801715.

2009

Miller, D.L., and Roth M. (2009) C.elegans are Protected from Lethal Hypoxia by an Embryonic Diapause. Curr. Bio. 19(14) 1233-1237. PMCID: PMC Journal

Frazier, H.N., and Roth M. (2009) Adaptive sugar provisioning controls survival of C. elegans embryos in adverse environments. Curr. Bio. 19(10) 859-63. PMCID: PMC2747774.


2008

Chan, K., and Roth M. (2008) Anoxia-induced suspended animation in budding yeast as an experimental paradigm for studying oxygen-regulated gene expression. Eukaryot Cell. 7(10): 1795-808. PMCID: PMC2568055.

Morrison, M., Blackwood, J. E., Lockett, S.L., Iwata, A., Winn, R.K., and Roth M. (2008) Surviving blood loss using hydrogen sulfide. Journal of Trauma, Injury, Infection and Critical Care 65(1): 183-8. PMID: 18580516.


2007

Miller, D.L., and Roth M. (2007) Hydrogen sulfide increases thermotolerance and lifespan in Caenorhabditis elegans., Proceedings of the National Academy of Sciences of the United States of America, 104 (51), 20618-22. PMCID: PMC2154480.

2006

Sundararajan, N., Mao, D., Chan, S., Koo, T.-W., Su, X., Sun, L., Zhang, J., Sung, K.-b., Yamakawa, M., Gafken, P.R., Randolph, T., McLerran, D., Feng, Z., Berlin, A.A., and Roth M. (2006) Ultrasensitive Detection and Characterization of Posttranslational Modifications Using Surface-Enhanced Raman Spectroscopy. Anal. Chem.: 78(11), 3543-3550


2005

Blackstone E.A., Morrison M.L., and Roth M. (2005) Hydrogen Sulfide Induces a Suspended Animation-Like State in Mice. Science. 308(5721): 518.

Moore, L.L., Stanvitch, G., Roth M, and Rosen, D. (2005) HCP-4/CENP-C promotes the prophase timining of centromere resolution by enabling the centromere association of HCP-6 in Caenorhabditis elegans. Mol. Cell Bio. 25(7): 2583-92. PMCID: PMC1061647.


2004

Nystul T.G., Roth M. (2004) Carbon monoxide-induced suspended animation protects against hypoxic damage in Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 101(24): 9133-6. PMCID: PMC428485.

Stear, J.H., Roth M. (2004) The C. elegans Kinetochore Reorganizes at Prometaphase and in Response to Checkpoint Stimuli. Mol Biol. Cell 13: 1473-1483. PMCID: PMC524797.

2002

Padilla, P.A., Nystul, T.G., Zager R.A., Johnson Ali C.M., and Roth, Mark B. (2002) Dephosphorylation of cell-cycle regulated proteins correlates with anoxia-induced suspended animation in Caenorhabitis elegans. Mol Biol. Cell 13: 1473-1483. PMCID: PMC111120.

Frank, D.J., Edgar, B.A., and Roth M.B. (2002) The Drosophila melanogaster gene brain tumor negatively regulates cell growth and ribosomal RNA synthesis. Dev 129:399-407.

Stear J.H. and Roth M.B. (2002) Characterization of HCP-6, a C. elegans protein required to prevent twisting and merotelic attachment. Genes Dev. 16: 1498-1508. PMCID: PMC186334.

2001

Padilla A. and Roth M. (2001) Oxygen deprivation causes suspended animation in the zebrafish embryo. Proceedings of the National Academy of Sciences of the United States of America, 98:7331-7335.

Moore, L. and Roth M. (2001) HCP-4, a CENP-C-like protein in C. elegans, is required for resolution sister centromeres. JCB 153:1199-1207.

2000

Neugebauer, K.M., Merrill, J.T., Wener, M.H., Lahita, R.G., Roth, M. (2000) SR proteins are autoantigens in patients with systemic lupus erythematosis Arthritis Rheum 43(8):1768-1778.


1999

Moore, L.L., Morrison, M., Roth M. (1999) HCP-1 protein involved in chromosome segregation, is localized to the centromereof mitotic chromosomes in C. elegans.JCB 147:471-479.

Buchwitz, B.J., Ahmad, K., Moore, L.L., Roth, M.D. and Henikoff, S. (1999) A histone-H3-like protein in C. elegans. Nature 401:547-548.

Tuma, R.S. and Roth, M.B. (1999) Induction of coiled body biogenesis in Xenopus oocytes by U7 snRNA. Chromosoma 108:337-344.

Stark, M.J., Cooper, T.A., Roth, M.B. (1999) The relative strengths of SR protein-mediated associations of alternative and constitutive exons can influence alternative splicing. J Biol Chem 274:29838-29842.

1998

Frank, D.J., and Roth, M.B. (1998) nc1-1 is required for the regulation of cell size and ribosomal RNA synthesis in C. elegans. J Cell Biol, 140(6):1321-1329.

Stark, J.M., Bazett-Jones, D., Herfort, M., and Roth, M.B. (1998) SR proteins are sufficient for exon bridging across an intron. Proceedings of the National Academy of Sciences of the United States of America, 95:2163-2168.

1997

Neugebauer, K.M. and Roth, M.B. (1997) Transcriptions units as RNA processing units. Genes Dev 11:3279-3285.

Morrison, M. Harris, K.S., and Roth, M.B. (1997) smg mutants affect the expression of alternatively spliced SR protein mRNAs in C. elegans. Proceedings of the National Academy of Sciences of the United States of America, 94(18), 9782-9785.

Neugebauer, K.M. and Roth, M.B. (1997) Distribution of pre-mRNA splicing factors at sites of RNA polymerase II transcription. Genes Dev,11(9):1148-1159.

1995

Ramchatesingh, J., Zahler, A.M., Neugebauer, K.M., Roth, M.B., and Cooper, T.A. (1995) A subset of SR proteins activates splicing of the cardiac troponin T alternative exon by direct interactions with an exonic enhancer. Mol Cell Biol 15(9):4898-4907.

Neugebauer, K.M., Stolk, J.A., and Roth, M.B. (1995) A conserved epitope on a subset of SR proteins defines a larger family of pre-mRNA splicing factors. J Cell Biol 129(4):899-908.

Roth, M. (1995) Nucleus and Gene Expression: Spheres, coiled bodies, and nuclear bodies. Curr Opin Cell Biol 7(3):325-328.

Zahler, A.M., and Roth, M.B. (1995) Distinct functions of SR proteins in recruitment of U1 small nuclear Ribonucleoprotein to alternative 5' splice sites. Proceedings of the National Academy of Sciences of the United States of America, 92:2642-2646.

1993

Tuma, R.S., Stolk, J.A., and Roth, M.B. (1993) Identification and characterization of a sphere organelle protein. J Cell Biol 122:767-773.

Zahler, A.M., Neugebauer, K.M., Stolk, J., and Roth, M. (1993) Human SR proteins and isolation of a cDNA encoding SRp75. Mol Cell Biol 13:4023-4028.

Zahler, A.M., Neugebauer, K.M., Lane, W.S., and Roth, M. (1993) Distinct functions of SR proteins in alternative pre-mRNA splicing. Science 260:219-222.

1992

Zahler, A.M., Lane, W.S., Stolk, J.A., and Roth, M. (1992) SR proteins: A conserved family of pre-mRNA splicing factors. Genes Dev 6:837-847.

Mayeda, A., Zahler, A.M., Krainer, A.R., and Roth, M. (1992) Two members of a conserved family of nuclear phosphoproteins are involved in pre-mRNA splicing. Proceedings of the National Academy of Sciences of the United States of America, 89:1301-1304.

1991

Roth, M.B., Zahler, A.M., and Stolk, J.A. (1991) A conserved family of nuclear phosphoproteins localized to sites of polymerase II transcription. J Cell Biol 115:587-596.

1990

Roth, M., Murphy C., and Gall, J.G. (1990) A monoclonal antibody that recognizes a phosphorylated epitope stains lampbrush chromosome loops and small granules in the amphibian germinal vesicle. J Cell Biol 111:2217-2223.

1989

Roth, M.B., and Gall, J.G. (1989) Targeting of a chromosomal protein to the nucleus and to lampbrush chromosome loops. Proceedings of the National Academy of Sciences of the United States of America, 1269-1272.

1987

Roth, M.B., and Gall, J.G. (1987) Monoclonal antibodies that recognize transcription unit proteins on Newt lampbrush chromosomes. J Cell Biol 105:1047-1054.

1985

Roth, M.B., and Prescott, D.M. (1985) DNA intermediates and telomere addition during genome reorganization in Euplotes crassus. Cell 41:411-417.

Roth, M.B., and Prescott, D.M. (1985) DNA reorganization during macronuclear development in a ciliate. IN: Genome Reorganization, pp 05-219. Alan R. Liss, Inc.

Roth, M.B., Lin, M., and Prescott, D.M. (1985) Large scale synchronous mating and the study of macronuclear development in Euplotes crassus. J Cell Biol 101:79-84

1979

Sprague, K.U., Roth, M.B., Manning, R.F., and Gage, L.P. (1979) Alleles of the fibroin gene coding for proteins of different lengths. Cell 17:407-413