Lab Members
Aude Chapuis, MD
Title:
Principal Investigator
Phone:
206.667.4369
Email:
achapuis@fredhutch.org
Clinical Research Division, Program in Immunology
Endowed Chair: John C. and Karyl Kay Hughes Endowed Chair
View faculty profile
Bo Lee
Title:
Lab Manager/Staff Scientist
Email:
blee2@fredhutch.org
Area of Responsibility:
Bo is working to develop target reporters to identify the targets of anti-tumor T cells residing in the tumors of cancer patients. She is also assisting in developing processes to support clinical products and IND generation to enable clinical trial initiation.
Yuta Asano
Title:
Post Doctoral Research Fellow
Email:
yasano@fredhutch.org
Area of Responsibility:
Yuta is working on development of T-cell immunotherapy for Merkel cell carcinoma. Outside the lab, he enjoys bouldering and chilling with his cat.
Sinéad Kinsella, PhD
Title:
Staff Scientist
Email:
skinsell@fredhutch.org
Area of Responsibility:
Sinéad is focused on TCR discovery and metabolic regulation of antigen presentation across multiple tumor types.
Previously, Sinéad’s research has centered on the molecular mechanisms of immune regeneration and enhancing immune function in response to cytoreductive therapies.
Tianzi Zhang
Title:
Post Doctoral Research Fellow
Email:
tzhang2@fredhutch.org
Area of Responsibility:
Tianzi is working on developing a high-throughput screening system that enables rapid patient-specific CD8+ TCR-antigen pair discovery. By using single-cell transcriptomic sequencing and TCR sequencing, the TCRs with high antigen specificity and anti-tumor reactivity will be engineered in lab and translated into the clinic.
Elise Wilcox, PhD
Title:
Post Doctoral Research Fellow
Email:
ewilcox@fredhutch.org
Area of Responsibility:
Elise studies how different versions of the proteosome, a complex which breaks proteins down into peptides presented on the cell surface, affect immune recognition by T cells. The goal is to prevent cancer from evading treatment and to determine which T cell receptors recognize peptides made by all versions of the proteosome. Outside of the lab, she loves running, baking, and flying planes.
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© 2023 Fred Hutchinson Cancer Center, a 501(c)(3) nonprofit organization.
© 2023 Fred Hutchinson Cancer Center, a 501(c)(3) nonprofit organization.