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2020 | 2019 | 2018 |  2017 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2004


Cai EY, Kufeld MN, Schuster SL, Arora S, Larkin M, Germanos AA, Hsieh AC, Beronja S. (2020). "Selective translation of cell fate regulators mediates tolerance to broad oncogenic stress.Cell Stem Cell doi: 10.1016/j.stem.2020.05.007

Itani OA, Zhong X, Tang X, Scott BA, Yan JY, Flibotte S, Lim YHsieh AC, Bruce JE, Van Gilst M, Crowder M. (2020). “Coordinate Regulation of Ribosome and tRNA Biogenesis Controls Hypoxic Injury and Translation” Current Biology doi: 10.1016/j.cub.2020.10.001

Diamantopoulos LN, Khaki AR, Grivas P, Gore JL, Schade GR, Hsieh AC, Lee JK, Yezefski T, Yu EY, Schweizer MT, Cheng HH, Psutka SP, Lin DW, Tretiakova MS, Vakar-Lopez F, Montgomery RB, Wright JW. (2020). "Plasmacytoid bladder cancer variant: response to chemotherapy and oncologic outcomes.Bladder Cancer doi: 10.3233/BLC-190258

Diamantopoulos LN, Holt SK, Khaki AR, Sekar RR, Gadzinski A, Nyame YA, Vakar-Lopez F, Tretiakova MS, Psutka SP, Gore JL, Lin DW, Schade GR, Hsieh AC, Lee JK, Yezefski T, Schweizer MT, Cheng HH, Yu EY, True LD, Montgomery RB, Grivas P, Wright JL. (2020). "Response to neoadjuvant chemotherapy and survival in micropapillary urothelial carcinoma: data from a tertiary referral center and Surveillance, Epidemiology, and End Results (SEER) program." Clinical Genitourinary Cancer doi: 10.1016/j.clgc.2020.10.002


Liu Y*, Horn JL*, Banda K*,  Goodman AZ, Lim Y, Jana S, Arora S, Germanos AA, Wen L, Hardin WR, Yang YC, Coleman IM, Tharakan RG, Cai EY, Uo T, Pillai SPS, Corey E, Morrissey C, Chen Y, Carver BS, Plymate SR, Beronja S, Nelson PS, Hsieh AC. (2019). "Androgen receptor regulates a druggable translational regulon in advanced prostate cancer.Science Translational Medicine doi: 10.1126/scitranslmed.aaw4993 *co-first authors

Kuppers DA, Arora S, Lim Y, Lim A, Carter L, Corrin P, Plasier CL, Basom R, Delrow J, Wang S, He HH, Torok-Storb B, Hsieh AC*, Paddison PJ*. (2019). "N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis.Nature Communications doi: 10.1038/s41467-019-12518-6 *co-corresponding author

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Schuster SL, Hsieh AC. (2019). "The untranslated regions of mRNAs in cancer.Trends in Cancer doi: 10.1016/j.trecan.2019.02.011

Winters BR*, De Sakar N*, Arora S, Bolouri H, Jana SVakar-Lopez F, Cheng HH, Schweizer MT, Yu EY, Grivas, P, Lee JK, Kollath L, Holt SK, McFerrin L, Ha G, Nelson PS, Montgomery RB, Wright JL#, Lam H#, Hsieh AC#. (2019). "Genomic distinctions between metastatic lower and upper tract urothelial carcinoma revealed through rapid autopsy.JCI Insight doi: 10.1172/jci.insight.128728 *co-first authors #co-corresponding author

Labrecque, MP, Coleman IM, Brown LG, True LD, Kollath J, Lakely B, Nguyen HM, Yang YC, Kaipainen AH, Coleman RT, Higano CS, Yu EY, Cheng HH, Mostaghel EA, Montgomery RB, Schweizer MT, Hsieh AC, Lin DW, Corey E, Nelson PS, Morrissey C. (2019). "Molecular profiling stratifies diverse phenotypes of treatment-refractory metastatic castration-resistant prostate cancer.JCI doi: 10.1172/JCI128212

Schweizer M, Antonarakis E, Bismar T, Guedes L, Cheng HH, Tretiakova M, Vakar-Lopez F, Klemfuss N, Konnick E, Mostaghel E, Hsieh AC, Nelson PS, Yu E, Montgomery B, True L, Epstein J, Lotan T, Pritchard C. (2019). "Genomic characterization of prostatic ductal adenocarcinoma identifies a high prevalence of DNA repair gene mutations.JCO Precision Oncology doi: 10.1200/PO.18.00327

Diamantopoulos LN, Winters BR, Grivas P, Ngo SD, Zeng J, Hsieh AC,  Gore JL, Liao JJ, Yu EY, Schade GR, Psutka SP, Schweizer MT, Lee JH, Dighe M, Lin DW, Cheng HH, Daya J, Tretiakova MS, True LD, Russell KJ, Vakar-Lopez F, Montgomery RB, Wright JL. (2019). "Bladder Cancer Multidisciplinary Clinic (BCMC) model influences disease assessment and impacts treatment recommendations.Bladder Cancer doi: 10.3233/BLC-190239


Graham LBanda K, Pisano, K, Shelley G, Curley T, Scher HI, Lotan TL, Hsieh AC*, Rathkopf DE*. (2018).  "A Phase II Study of the Dual mTOR Inhibitor MLN0128 in Patients with metastatic castration-resistant prostate cancer." (2018). Investigational New Drugs doi: 10.1007/s10637-018-0578-9 *co-corresponding author

Guzzi N, Ciesla M, Ngoc P, Lang S, Arora S, Dimitrious M, Pimkova K, Sommarin MNE, Munita R, Lubas M, Lim Y, Okuyama K, Soneji S, Karlsson G, Hansson J, Jonsson G, Lund AH, Sigvardsson M, Hellstrom-Lindberg E, Hsieh AC, Bellodi C. (2018). "Pseudouridylation of tRNA-derived fragments steers translational control in stem cells.Cell doi: 10.1016/j.cell.2018.03.008

Nguyen HG, Conn CS, Kye Y, Xue L, Forester CM, Cowan JE, Hsieh AC, Cunningham JT, Truillet C, Tameire F, Evans MJ, Evans CP, Yang J, Hann B, Koumenis C, Walter P, Carroll PR, Ruggero D. (2018). "Development of a stress response therapy targeting aggressive prostate cancer.Science Translational Medicine doi: 10.1126/scitranslmed.aar2036

Winters BR, Vakar-Lopez F, Brown L, Montgomery RB, Seiler R, Black P, Boormans JL, Dall'Era M, Davincioni E, Douglas J, Gibb E, Van Rhijn BWG, Van der Heijden M, Hsieh AC, Wright JL, Lam H. (2018) "Mechanistic target of rapamycin (mTOR) protein expression in the tumor and its microenvironment correlates with more aggressive pathology at cystectomy.Urologic Oncology doi: 10.1016/j.urolonc.2018.03.016


Bluemn, EG, Coleman I, Lucas JM, Coleman R, Hernandez-Lopez S, Tharakan R, Bianchi-Frias D, Dumpit R, Kaipainen A, Corella A, Yang YC, Nyquist M, Mostaghel E, Hsieh AC, Zhang X, Corey E, Brown L, Nguyen H, Pienta K, Ittman M, Schweizer M, True L, Wise D, Rennie PS, Vessella R, Morrissey C, Nelson PS. (2017). "Androgen receptor pathway-independent prostate cancer is sustained through FGF signaling.Cancer Cell doi: 10.1016/j.ccell.2017.09.003

Jana SHsieh AC, Gupta R. (2017). "Reciprocal amplification of caspase-3 activity by nuclear export of a putative human RNA-modifying protein, PUS10 during TRAIL-induced apoptosis.Cell Death & Disease doi: 10.1038/cddis.2017.476

Wei XX, Hsieh AC, Kim W, Friedlander TW, Lin AM, Louttit M, Ryan CJ. (2017). "A phase I study of abiraterone acetate combined with BEZ235, a dual PI3K/mTOR inhibitor, in metastatic castration resistant prostate cancer.The Oncologist doi: 10.1634/theoncologist.2016-0432

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Hsieh AC*, Nguyen HG, Wen L, Edlind MP, Carroll P, Kim W, Ruggero D.* (2015). "Cell type-specific abundance of 4EBP1 primes prostate cancer sensitivity or resistance to PI3K pathway inhibitors.Science Signaling doi: 10.1126/scisignal.aad5111 *co-corresponding author

Sheridan CM, Grogan T, Nguyen HG, Rettig M*, Hsieh AC*, Ruggero D.*  (2015). "YB-1 and MTA1 protein levels and not DNA or mRNA alterations predict for prostate cancer recurrence."Oncotarget doi: 10.18632/oncotarget.3477  *co-corresponding author

Publications prior to joining Fred Hutch


Edlind MP, Hsieh AC. (2014). "PI3K-AKT-mTOR signalling in prostate cancer progression and androgen deprivation therapy resistance." Asian Journal of Andrology doi: 10.4103/1008-682X.122876

Long-Cheng L, Hsieh AC, Ruggero D, Greene KL, Carroll PR. (2014). Molecular basis of prostate cancer. In: The Molecular Basis of Cancer, 4th Edition. Mendelsohn J, Howley P, Israel M, Gray J, Thompson C. (eds).  doi: 10.1016/B978-1-4557-4066-6.00038-X


Olshen AB, Hsieh AC, Stumpf CR, Olshen RA, Ruggero D, Taylor BS. (2013). "Assessing gene-level translational control from ribosome profiling.Bioinformatics doi: 10.1093/bioinformatics/btt533


Hsieh AC*, Liu Y*, Edlind MP, Ingolia, NT, Janes MR, Sher A, Shi EY, Christensen C, Stumpf CR, Bonham MJ, Wang S, Ren P, Martin M, Jessen K, Feldman ME, Weissman JS, Shokat KM, Rommel C, Ruggero D. (2012)."The translational landscape of mTOR signaling steers cancer initiation and metastasis.Nature doi: 10.1038/nature10912 *co-first author


Hsieh AC, Truitt ML, Ruggero D. (2011). "Oncogenic AKTivation of translation as a therapeutic target.British Journal of Cancer doi: 10.1038/bjc.2011.241

Kondrashov N, Pusic A, Stumpf, CR, Shimizu K, Hsieh AC, Ishijima J, Kikkawa Y, Shiroishi T, Barna M. (2011). "Ribosome-mediated specificity of Hox mRNA translation and vertebrate tissue patterning.Cell doi: 10.1016/j.cell.2011.03.028

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Hsieh AC*, Costa M*, Zollo O, Davis C, Feldman M, Testa JR, Meyuhas O, Shokat K, Ruggero D. (2010). "Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E.Cancer Cell doi: 10.1016/j.ccr.2010.01.021 *co-first author  

Hsieh AC, Ruggero D. (2010). "Targeting eukaryotic translation initiation factor 4E (eIF4E) in cancer.Clinical Cancer Research doi: 10.1158/1078-0432.CCR-10-0433 


Mawad R, Hsieh AC, Damon L. (2009) "Graft-versus-Host Disease presenting with pancytopenia after en-bloc multi-organ transplant: case report and literature review.Transplantation Proceedings doi: 10.1016/j.transproceed.2009.06.229


Hsieh AC, Ryan CJ. (2008). "Novel concepts in androgen receptor blockade.Cancer Journal doi: 10.1097/PPO.0b013e318161d13e


Hsieh AC, Moasser MM. (2007). "Targeting HER proteins in cancer therapy and the role of the non-target HER3.British Journal of Cancer doi: 10.1038/sj.bjc.6603910

Hsieh AC*, Small EJ, Ryan CJ. (2007). "Androgen-response elements in hormone-refractory prostate cancer: implications for treatment development.Lancet Oncology doi: 10/1016/S1470-2045(07)70316-9 *corresponding author 


Hsieh AC, Bo R, Manola J, Vazquez F, Bare O, Khvorova A, Scaringe S, Sellers WR. (2004). "A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: determinants of gene silencing for use in cell-based screens.Nucleic Acid Research doi: 10/1093/nar/gkh238