Professor, Human Biology and Public Health Sciences Division
Endowed Chair for Graduate Education
2003-present
Research Associate Professor, Human Biology, Fred Hutch
Affiliate Associate Professor, UW Department of Global Health
Faculty Consultant, Office of Education and Training, Fred Hutch
Lehman Lab
myNCBI
2016-present
I study the evolution of human antibody responses directed against HIV-1 infection. We sequence antibody genes from B cells within longitudinal patient blood samples to estimate how their HIV-specific antibody lineages developed.
2022-present
I study the evolution of broad neutralizing antibodies to viruses such as HIV-1 and SARS-CoV-2. More specifically, I aim to discover the antigens required to elicit their development, in view to inform vaccine design. I also have a strong interest in global public health and translating research into practical applications.
2019-present
I study mechanisms of adaptive and innate immunity against emerging and endemic human coronaviruses.
2023-present
I am broadly interested in early life immunity to viral infections. I study how recurrent CMV activation impacts HIV reservoir clonality in a longitudinal cohort of Kenyan children living with HIV
2020-present
I am interested in studying mechanisms of innate and adaptive immunity to emerging viruses, including Zika virus and SARS-CoV-2.
2008-present
I perform Gen Probe QC HIV viral RNA loads and population based sequencing for resistant mutations for women on ARV for the QRS cohort. I’ve also been involved with neutralization assays using the PBMC and TZM methods for PBMC and 293T-passaged chimeras with monoclonal antibodies.
2019-present
I am interested in studying the diversity and evolution of HIV-1 in Kenyan infants to understand the timing of infection.
2021-present
I am interested in the relationship between infectious diseases and their hosts. Specifically, I will study how immune responses correlate with HIV clearance in Kenyan infants.
2021-present
I am interested in studying immune responses to SARS-CoV-2; specifically, antibody responses to SARS-CoV-2 breakthrough infections in vaccinated individuals.
2014-present
Co-mentored with Erick Matsen
2020-present
Co-mentored with Erick Matsen
2017-present
Co-mentored with Jesse Bloom
2020-present
Co-mentored with Erick Matsen