Group Members

Joshua T Schiffer, MD, MSc

Principal Investigator

I am Professor in the Vaccine and Infectious Disease and Clinical Research Divisions at the Fred Hutchinson Cancer Center and an Associate Professor at the University of Washington in the Division of Allergy and Infectious Diseases, Department of Medicine. I love identifying problems in the clinic and the infectious diseases literature that can be addressed with mathematical models. I feel privileged to collaborate with such a driven and gifted group of multi-disciplinary scientists and clinicians at Fred Hutch and the University of Washington.

Daniel Reeves, PhD

Senior Staff Scientist, Fred Hutch; Affilite Assistant Professor, Department of Global Health, UW

I use a broad range of mathematical tools ranging from statistical physics, ecology, pharmacology, and epidemiology to inform vaccination, treatments, and cures for infectious diseases like SARS-CoV-2 and HIV. You can find out more on my Fred Hutch profile and www.dbrvs.org (personal). 

Shadi Esmaeili-Wellman, PhD

Staff Scientist

I am a statistical physicist by training, graduated from Virginia Tech in 2019. My burning desire to understand the complexity and interconnectedness of the human body sparked during my sister’s battle with cancer and only grew over time.  After three years of post-graduate work at the interface between modeling ecological systems with statistical physics, I joined the fantastic, diverse group of scientists at the Vaccine and Infectious Disease Division to understand and model the virus dynamics and its interaction with the immune system. Here at Schiffer’s group, I’m modeling gene drive technology in herpes viruses and the pharmacokinetic and pharmacodynamic modeling of combination therapy and simulating a clinical trial.

Lucero Rodriguez Rodriguez, PhD

Post-Doctoral Research Fellow

I'm an applied mathematician who studied at the University of Texas Rio Grande Valley before earning my Ph.D. in Applied Mathematics for the Life and Social Sciences from Arizona State University in 2024. I joined the Schiffer Group in early 2025 to use mathematical modeling to study the complex systems that arise at the cellular level, particularly in the context of the human immune system and HIV infection. My current research focuses on modeling the evolutionary dynamics of HIV to better understand the persistence of the viral reservoir and to help identify which therapeutics are most effective at different stages of infection.

Katherine Owens, PhD

Post-Doctoral Research Fellow

I studied mathematics at Willamette University and applied mathematics at the University of Washington before joining the Schiffer group as a post-doctoral research fellow in spring 2022. I am excited about using mechanistic mathematical models to address open questions in biology and medicine. In my current work, I aim to understand the within-host dynamics and evolution of SARS-CoV-2 during infection in order to inform optimal treatment plans for immunocompromised patients and clinical trial design.

Felix Yuan

Research Intern

I'm an undergraduate student at Colubmia University studying math. I'm especially interested in the application of math and computational theories and tools to biomedical research. 

Alumni

Ugo Avila-Ponce de Leon, PhD

Subhasish Baral, PhD

Postdoctoral Reseracher, Emory University

Catherine Byrne

E. Fabian Cardozo-Ojeda, PhD

Director of Modeling & Simulation, Xencore

Elizabeth Duke, MD

Palo Alto VA

Salisu Garba, PhD

Principal Scientist, Merck

Ashish Goyal, PhD

Principal Scientist, Vertex

Jonah Hall

Graduate Student, University of British Columbia

Elizabeth Krantz, MS

Statistical Research Associate

Yubi Mamiya

Undergraduate, Princeton University

Laura Matrajt

Staff Scientist, Fred Hutch

Bryan Mayer

Sr Staff Scientist, Fred Hutch

Makayla Poindexter

Biomedical Engineering Student at NC State University


 

Pavitra Roychoudhury, PhD

Research Assistant Professor, UW

David Swan, MS, MME

Bioinformatics Analyst

Florencia Tettamanti Boshier, PhD

Associate Director, Systems Medicine, AstraZeneca

Shuang Xu

Associate Scientist, Certara

Shuyi (Judy) Yang

Graduate Student, University of California, Berkeley