Publications

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Molecular profiling of invertebrate glia  
Glia (2024). PMID: 39415317. Purice M, Lago-Baldaia I, Fernandes V*, Singhvi A*. (invited review, for special issue release, early publication online)

Glia in nervous system development and function in C. elegans
CSHL press textbook “Glia” (2024). 2nd edition. PMID: 38565269. Singhvi A*, Shaham S*, Rapti G*. Invited chapter on C. elegans glia. 

The complete molecular atlas of adult C. elegans glia across sexes
bioRxiv (2023). PMID: 36993469. Purice MD, Quitevis EJA, Manning RS, Severs LJ, Tran NT, Sorrentino V, Setty M*, Singhvi A*.

Neuron cilia restrain glia KCC-3 to a microdomain to regulate multi-sensory processing
Cell Reports (2024). bioRxiv (2023). PMID: 38421867. Ray S, Gurung P, Manning RS, Kravchuk A, Singhvi A*.  
In News:

NIH Director's Spotlight
Science Daily
EurekaAlert
Fred Hutch News: Glial cells are more than our brain’s glue
Fred Hutch Science Spotlight: Neuron-glia love triangles at single-cell resolution

Epithelial UNC-23 limits mechanical stress to maintain glia-neuron architecture
Developmental Cell (2024). bioRxiv (2022). PMID: 38670103. Martin C, Bent J, Hill T, Topalidou I, Singhvi A*.
In News:

Fred Hutch Science Spotlight: Epithelial cells prevent neurons from meandering
Fred Hutch News: Sniffing out new discoveries

Glia in invertebrate models: insights from Caenorhabditis elegans
Invited book chapter, Springer Nature textbook (2024), “Astrocyte-Neuron Interactions in Health and Disease”. PMID: 39190070.  Purice M*, Severs LJ*, Singhvi A.

Editorial: Accessory cells of sensory systems and their functional roles
Frontiers in Neuroscience (2022). PMID: 35844212. Ackerman SD, Singhvi A, Bianchi L*.

Multiplexing thermotaxis behavior measurement in Caenorhabditis elegans
Bio-Protocols (2022). PMID: 35530512. Raiders S, Klein M*, Singhvi A*.

Charging up the periphery: glial ionic regulation in sensory perception 
Frontiers in Cell and Developmental Biology (2021). PMID: 34458255. Ray S and Singhvi A*.

Engulfed by glia: glial pruning in development, function, and injury across species 
Jounrnal of Neuroscience (2021). PMID: 33468571. Raiders S, Han T, Scott-Hewitt N, Kucenas S, Lew D, Logan MA, Singhvi A.

Glia actively sculpt sensory neurons by controlled phagocytosis to tune animal behavior
eLife, 2 (2021). PMID: 33759761. Raiders S, Black EC, Bae A, MacFarlane S, Shaham S, Singhvi A*.
In News:

eLife Digest
Fred Hutch Science Spotlight: Too much of a good thing: pruning neurons to control behavior
Faculty Opinions: A. Ghosh Roy

Age-dependent changes in response property and morphology of a thermosensory neuron and thermotaxis behavior in Caenorhabditis elegans
Aging Cell (2020). PMID: 32307902. Huang TT, Matsuyama HJ, Tsukada Y, Singhvi A, Syu RT, Lu Y, Shaham S, Mori I*, Pan CL*.

Glia-neuron interactions in Caenorhabditis elegans
Annual Review of Neuroscience (2019). PMID: 30883261. Singhvi A and Shaham S.

Physical exertion exacerbates decline in the musculature of an animal model of Duchenne muscular dystrophy
Proceedings of the National Academy of Sciences (PNAS) (2019). PMID: 30755520. Hughes KJ, Rodriguez A, Flatt KM, Ray S, Schuler A, Rodemoyer B, Veerappan V, Cuciarone K, Kullman A, Lim C, Gutta N, Vemuri S, Andriulis V, Niswonger D, Barickman L, Stein W, Singhvi A, Schroeder NE, Vidal-Gadea AG*.

A glial K/Cl transporter controls neuronal receptive-ending shape by chloride inhibition of an rGC
Cell (2016). PMID: 27062922. Singhvi A, Liu B, Friedman CJ, Fong J, Lu Y, Huang XY, Shaham S*.
In News:

Preview by Sun, LO and Barres, B in Cell. “Glia get neurons in shape”
Editor’s Choice by Wong, W in Science Signaling. “Glia dictate neuronal morphology”
Rockefeller NewsWire
F1000 Recommendation by Jenny, A

PROS-1/Prospero is a major regulator of the glia-specific secretome controlling sensory neuron structure and function in C. elegans
Cell Reports (2016). PMID: 27068465. Wallace SW, Singhvi A, Liang Y, Lu Y, Shaham S*.

Asymmetric neuroblast divisions producing apoptotic cells require the cytohesin GRP-1 in Caenorhabditis elegans
Genetics (2014). PMID: 25053664. Teuliere J, Cordes S, Singhvi A, Talavera K, Garriga G.

The Arf GAP CNT-2 regulates the apoptotic fate in C. elegans asymmetric neuroblast divisions
Current Biology (2011). PMID: 21596567. Singhvi A, Teuliere J, Talavera K, Cordes S, Ou G, Vale RD, Prasad BC, Clark SG, Garriga G*.

Building a sustainable career in science
Nature Biotechnology (2010). PMID: 20379181. Singhvi A* and Sachdev P*.

What else can we do to enhance the scientific potential of India? 
Current Science, 99: 432-3 (2010). Singhvi A and Singhvi AK.

Asymmetric cell divisions, aggrosomes and apoptosis
Trends in Cell Biology (2009). PMID: 19091567. Singhvi A and Garriga G*.

The T-box gene tbx-2 and the homeobox gene egl-5 specify neural fate in the HSN/PHB lineage
Genetics (2008). PMID: 18505863. Singhvi A, Frank CA, Garriga G*.

Taste representations in the Drosophila brain
Cell (2004). PMID: 15210117. Wang Z, Singhvi A, Kong P, Scott K*.

F1000 Recommendation by Luo, L and Hildebrand, J