Neuron and Glia -inseparable sisters in the Labyrinth of Thought,
Fingers intertwined, singing in strange argot.
Yet, identical peas in a pod? Certainly not.
Neuron, full of action and potential; her electrifying intelligence a legend.
Glia, shy and soft-spoken; helping, cooking and ever running an errand.
Naturally then, Neuron often commanded the attention scend.
Still, Cajal found Glia more enigmatic than she showed; he was prescient!
When biologists realized that even Neuron heeded Glia’s counsel to be efficient,
They started forging tools to translate the sisters’ descant…
A. Singhvi, 2016
Glia actively sculpt sensory neurons by controlled phagocytosis to tune animal behavior
Stephan Raiders, Erik Calvin Black, Andrea Bae, Stephen MacFarlane, Shai Shaham, Aakanksha Singhvi
Age-dependent changes in response property and morphology of a thermosensory neuron and thermotaxis behavior in Caenorhabditis elegans.
Huang TT, Matsuyama HJ, Tsukada Y, Singhvi A, Syu RT, Lu Y, Shaham S, Mori I, Pan CL.
Aging Cell. 2020 May;19(5):e13146.
Glia-Neuron Interactions in Caenorhabditis elegans.
Singhvi A and Shaham S
Annual Review of Neuroscience, 2019, 42:149-168.
Physical exertion exacerbates decline in the musculature of an animal model of Duchenne muscular dystrophy
K. J. Hughes, A. Rodriguez, K. M. Flatt, S. Ray, A. Schuler, B. Rodemoyer, V. Veerappan, K. Cuciarone, A. Kullman, C. Lim, N. Gutta, S. Vemuri, V. Andriulis, D. Niswonger, L. Barickman, W. Stein, A. Singhvi, N. E. Schroeder, A. G. Vidal-Gadea
Proceedings of the National Academy of Sciences (PNAS), 116 (9) 3508-3517.
A Glial K/Cl Transporter Controls Neuronal Receptive-Ending Shape by Chloride Inhibition of an rGC.
Singhvi A, Liu B, Friedman CJ, Fong J, Lu Y, Huang XY, Shaham S.
Cell, 165, 936-48.
Preview by Sun, LO and Barres, B in Cell. “Glia Get Neurons in Shape”
Editor’s Choice by Wong, W in Science Signaling. “Glia dictate Neuronal Morphology”
F1000 Recommendation by Jenny, A
A PROS-1/Prospero Is a Major Regulator of the Glia-Specific Secretome Controlling Sensory Neuron Structure and Function in C. elegans.
Wallace SW, Singhvi A, Liang Y, Lu Y, Shaham S.
Cell Reports, 15(3):550-62.
Asymmetric Neuroblast Divisions Producing Apoptotic Cells Require the Cytohesin GRP-1 in Caenorhabditis elegans
Teuliere J, Cordes S, Singhvi A, Talavera K, Garriga G.
Genetics, 198 (1), 229-47.
The ARF GAP protein, CNT-2 regulates asymmetric cell divisions in C. elegans.
Singhvi A, Teuliere J, Talavera K, Cordes S, Ou G, Vale RD, Prasad BC, Clark SG, Garriga G.
Current Biology, 21(11), 948-54.
Building a sustainable career in science.
Singhvi A and Sachdev, P.
Nature Biotechnology, 28(4), 378-9 (2010).
What else can we do to enhance the scientific potential of India?
Singhvi A and Singhvi AK.
Current Science, 99: 432-3 (2010).
Asymmetric cell divisions, aggrosomes and apoptosis. (Review)
Singhvi A and Garriga G.
Trends in Cell Biology, 19(1), 1.
The T-box gene tbx-2 and the homeobox gene egl-5 specify neural fate in the HSN/PHB lineage.
Singhvi A, Frank CA, Garriga G.
Genetics, 179(2), 887.
Taste representations in the Drosophila brain.
Wang Z, Singhvi A, Kong P, Scott K
Cell, 117 (7), 981-91.