Structures and Publications

2021 | 2020 | 2019 | 2018 | 2017


 

2021

Sholukh.JClinMicrobiol.2021

Sholukh.JClinMicrobiol.2021

 

 

Sholukh, A.M., Fiore-Gartland, A., Ford, E.S., Miner, M.D., Hou, Y.J., Tse, L.V., Kaiser, H., Zhu, H., Lu, J., Madarampalli, B., Park, A., Lempp, F.A., St Germain, R., Bossard, E.L., Kee, J.J., Diem, K., Stuart, A.B., Rupert, P.B., Brock, C., Buerger, M., Doll, M.K., Randhawa, A.K., Stamatatos, L., Strong, R.K., McLaughlin, C., Huang, M.L., Jerome, K.R., Baric, R.S., Montefiori, D., Corey, L.
Evaluation of Cell-Based and Surrogate SARS-CoV-2 Neutralization Assays
Journal of Clinical Microbiology (2021) 59(10):e0052721   2021 09 20

 

 

Finton.FrontImmunol.2021

Finton.FrontImmunol.2021

 

Finton, K.A.K., Brusniak, M.Y., Jones, L.A., Lin, C., Fiore-Gartland, A.J., Brock, C., Gafken, P.R., Strong, R.K.
ARTEMIS: A novel mass-spec platform for HLA-restricted self and disease-associated peptide discovery
Frontiers in immunology (2021) 12:658372


2020

CookSanger.SciTranslMed.2020

CookSanger.SciTranslMed.2020

 

Cook Sangar, M.L., Girard, E.J., Hopping, G., Yin, C., Pakiam, F., Brusniak, M.Y., Nguyen, E., Ruff, R., Gewe, M.M., Byrnes-Blake, K., Nairn, N.W., Miller, D.M., Mehlin, C., Strand, A.D., Mhyre, A.J., Correnti, C.E., Strong, R.K., Simon, J.A., Olson, J.M
A potent peptide-steroid conjugate accumulates in cartilage and reverses arthritis without evidence of systemic corticosteroid exposure
Science Translational Medicine  (2020) 12(533), eaay1041

  • cartilage-targeting cystine-dense peptide (CDP) #1       6ATM.pdb
  • cartilage-targeting cystine-dense peptide (CDP) #2       6ATY.pdb
  • cartilage-targeting cystine-dense peptide (CDP) #3       6AY7.pdb
  • cartilage-targeting cystine-dense peptide (CDP) #4       6AY8.pdb

 

 

Crook.JMolBiol.2020

Crook.JMolBiol.2020

 

 

Crook, Z.R., Girard, E., Sevilla, G.P., Merrill, M., Friend, D., Rupert, P.B., Pakiam, F., Nguyen, E., Yin, C., Ruff, R.O., Hopping, G., Strand, A.D., Finton, K.A., Coxon, M., Mhyre, A.J., Strong, R.K., Olson, J.M.
A TfR-binding cystine-dense peptide promotes blood-brain barrier penetration of bioactive molecules
Journal of Molecular Biology  (2020) 432(14), pp. 3989-4009

  • TfRB1G3                                                  6OKE.pdb 
  • TfRB1G3 in complex with hTfR          6OKD.pdb 

2019

Lopez-Yglesias.ImmunoHorizons.2019
Lopez-Yglesias.ImmunoHorizons.2019

 

Lopez-Yglesias, A.H., Lu, C.C., Zhao, X., Chou, T., Vanden Bos, T., Strong, R.K., Smith, K.D. 
FliC's Hypervariable D3 Domain Is Required for Robust Anti-Flagellin Primary Antibody Responses
ImmunoHorizons  (2019) 3(9), pp. 422-432

 

 

Bancroft.JExpMed.2019
Bancroft.JExpMed.2019

 

Bancroft, T., DeBuysscher, B.L., Weidle, C., Schwartz, A., Wall, A., Gray, M.D., Feng, J.,  Steach, H.R., Fitzpatrick, K.S., Gewe, M.M., Skog, P.D., Doyle-Cooper, C., Ota, T., Strong, R.K., Nemazee, D., Pancera, M., Stamatatos, L., McGuire, A.T., Taylor, J.J.
Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes
Journal of Experimental Medicine  (2019) 216(10), pp. 2331-2347

  • iglb12 scFv in complex with anti-idiotype ib2 Fab             6OL6.pdb
  • iglb12 Fab in complex with anti-idiotype ib3 Fab              6OL5.pdb

 

 

 

Clifton.JClinOncol.2019
Clifton.JClinOncol.2019

Clifton, M.C., Rupert, P.B., Hoette, T.M., Raymond, K.N., Abergel, R.J., Strong, R.K.
Parsing the functional specificity of Siderocalin/Lipocalin 2/NGAL for siderophores and related small-molecule ligands
Journal of Structural Biology: X (2019) 2 100008

Siderocalin-Ligand Complexes:


2018

Patient HLA Germline Variation and Transplant Survivorship
Petersdorf.JClinOncol.2018

Petersdorf, E.W., Stevenson, P., Malkki, M., Strong, R.K., Spellman, S.R., Haagenson, M.D., Horowitz, M.M., Gooley, T., Wang, T.
Patient HLA Germline Variation and Transplant Survivorship
Journal of Clinical Oncology  (2018) 36(24), pp. 2524-2531

 

 

Screening, large-scale production and structure-based classification of cystine-dense peptides
Correnti.NatStructMolBiol.2018

Correnti, C.E., Gewe, M.M., Mehlin, C., Bandaranayake, A.D., Johnsen, W.A., Rupert, P.B., Brusniak, M.Y., Clarke, M., Burke, S.E., De Van Der Schueren, W., Pilat, K., Turnbaugh, S.M., May, D., Watson, A., Chan, M.K., Bahl, C.D., Olson, J.M., Strong, R.K
Screening, large-scale production and structure-based classification of cystine-dense peptides
Nature Structural & Molecular Biology  (2018) 25(3), pp. 270-278

  • Scorpion Potassium Channel Toxin alpha-KTx 4.2               6ATL.pdb
  • Scorpion Potassium Channel Toxin alpha-KTx 4.5               6ATN.pdb
  • Scorpion Potassium Channel Toxin kappa-KTx 1.1               6ATS.pdb
  • Human Elafin                                                                                  6ATU.pdb
  • Scorpion Chlorotoxin                                                                    6ATW.pdb
  • Scorpion Potassium Channel Toxin gamma-KTx 2.2            6AU7.pdb
  • Scorpion Potassium Channel Toxin gamma-KTx 2.2            6AUP.pdb
  • Spider U5-theraphotoxin-Hs1b 1                                              6AV8.pdb
  • Scorpion Insectotoxin-I1                                                             6AVA.pdb
  • Scorpion Potassium Channel Toxin alpha-KTx 1.5                6AVC.pdb
  • Scorpion Potassium Channel Toxin alpha-KTx 6.9                6AVD.pdb

2017

Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets
Crook.NatComm.2017

Crook, Z.R., Sevilla, G.P., Friend, D., Brusniak, M.-Y., Bandaranayake, A.D., Clarke, M., Gewe, M., Mhyre, A.J., Baker, D., Strong, R.K., Bradley, P., Olson, J.M.
Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets
Nature Communications  (2017) 8:2244

 

 

Chelation and stabilization of berkelium in oxidation state +IV
Deblonde.NatChem.2017

Deblonde, G.J.P., Sturzbecher-Hoehne, M., Rupert, P.B., An, D.D., Illy, M.-C., Ralston, C.Y., Brabec, J., de Jong, W.A., Strong, R.K., Abergel, R.J.
Chelation and stabilization of berkelium in oxidation state +IV
Nature Chemistry   (2017) 9(9), pp. 843-849

  • Human Siderocalin + Californium          5KIC.pdb

 

 

Control of tumor initiation by NKG2D naturally expressed on ovarian cancer cells
Cai.Neoplasia.2017

Cai, X., Caballero-Benitez, A., Gewe, M.M., Jenkins, I.C., Drescher, C.W., Strong, R.K., Spies, T., Groh, V.
Control of tumor initiation by NKG2D naturally expressed on ovarian cancer cells
Neoplasia  (2017) 19(6), pp. 471-82