Bai Lab

Our Research

Welcome to the Bai Lab. Our goal is to understand how neurons talk to each other. Neuron communication underpins all cognitive and physical activities (i.e., movement, perception, learning, and memory). High quality communication is essential to maintain organism homeostasis and disruptions lead to severe consequences. The Bai Lab utilizes a combination of genetic, biochemical, imaging, and electrophysiological techniques to elucidate novel mechanisms governing neuron communication at the molecular, cellular, and circuit levels.
 


Featured Publications

The endophilin curvature-sensitive motif requires electrostatic guidance to recycle synaptic vesicles in vivo

Zhang L, Wang Y, Dong Y, Pant A, Liu Y, Masserman L, McLaughlin Jr RN, Bai J. Developmental Cell 2022

Dimensionality of locomotor behaviors in developing C. elegans

Hassinan CW*, Sterrett SC*, Summy B, Khera A, Wang A, and Bai J. PLoS Computational Biology 2024

Endocytic protein AP180 assembly domain regulates synaptic vesicle size and release in Caenorhabditis elegans

Wang Y*, Wu L*, Zhang L, Dong Y, Pant  A, Liu Y, Bai J. PLoS Biol 2026