See our most recent structures here.
Maps: EMD-20794, EMD-20797 to EMD-20802 & EMD-21125
Model: PDB: 6uja
Datasets: EMPIAR-10343 & EMPIAR-10344
Campbell MG, Cormier A, Ito S, Seed RI, Bondesson AJ, Lou J, Marks JD, Baron JL, Cheng Y, Nishimura SL. "Cryo-EM reveals a mechanism of integrin-mediated TGF-β activation within the latent TGF-β complex." Cell. 2020 Feb 6;180(3):490-501.e16.
Map: EMD-20795
Model: PDB: 6ujab
Dataset: EMPIAR-10345
Campbell MG, Cormier A, Ito S, Seed RI, Bondesson AJ, Lou J, Marks JD, Baron JL, Cheng Y, Nishimura SL. "Cryo-EM reveals a mechanism of integrin-mediated TGF-β activation within the latent TGF-β complex." Cell. 2020 Feb 6;180(3):490-501.e16.
Map: EMD-20796
Model: PDB: 6ujc
Campbell MG, Cormier A, Ito S, Seed RI, Bondesson AJ, Lou J, Marks JD, Baron JL, Cheng Y, Nishimura SL. "Cryo-EM reveals a mechanism of integrin-mediated TGF-β activation within the latent TGF-β complex." Cell. 2020 Feb 6;180(3):490-501.e16.
Map: EMD-7939
Model: PDB: 6djp
Cormier A, Campbell MG, Ito S, Wu S, Lou J, Marks J, Baron J, Nishimura SL, Cheng Y. "Cryo-EM structure of the αvβ8 integrin reveals a mechanism for stabilizing integrin extension." Nat Struct Mol Biol. 2018; 25(8):698–704.
Maps: EMD-7132 & EMD-7133
Models: PDB: 6bqr & 6bqv
Datasets: EMPIAR-10126 & EMPIAR-10127
Autzen HE, Myasnikov AG, Campbell MG, Asarnow D, Julius D, Cheng Y. "Structure of the human TRPM4 ion channel in a lipid nanodisc." Science. 2018; 359 (6372), 228-232.
Maps: EMD-8471
Model: PDB: 5tx1
Yu X, Veesler D, Campbell MG, Barry ME, Asturias FJ, Barry MA and Reddy VS. "Cryo-EM structure of human adenovirus D26 reveals the conservation of structural organization among human adenoviruses." Science Advances. 2017; 3(5):e1602670.
Map: EMD-6287
Model: PDB: 6bdf
Dataset: EMPIAR-10025
Campbell MG, Veesler D, Cheng A, Potter CS, Carragher B. "2.8 Å resolution reconstruction of the Thermoplasma acidophilum 20S proteasome using cryo-electron microscopy." eLife. 2015; 4:e06380.
Map: EMD-2791
Campbell MG, Kearney BM, Cheng A, Potter CS, Johnson JE, Carragher B, Veesler D. "Near-atomic resolution reconstructions using a mid-range electron microscope operated at 200kV." J Struct Biol. 2014; 188(2):183-187.
Model: EMD-2792
Campbell MG, Kearney BM, Cheng A, Potter CS, Johnson JE, Carragher B, Veesler D. "Near-atomic resolution reconstructions using a mid-range electron microscope operated at 200kV." J Struct Biol. 2014; 188(2):183-187.
Map: EMD-5754
Veesler D, Campbell MG, Cheng A, Fu C-Y, Murez Z, Johnson JE, Potter CS, Carragher B. "Maximizing the potential of electron cryomicroscopy data collected using direct detectors." J Struct Biol. 2013; 184(2):193–202.
Maps: EMD-5485 (Full); EMD-5487 (Spike)
Campbell MG, Cheng A, Brilot AF, Moeller A, Lyumkis D, Veesler D, Pan J, Harrison SC, Potter CS, Carragher B, Grigorieff N. "Movies of ice-embedded particles enhance resolution in electron cryo-microscopy." Structure. 2012; 20(11):1823–1828.
Maps: EMD-5486 (Full); EMD-5488 (Spike)
Campbell MG, Cheng A, Brilot AF, Moeller A, Lyumkis D, Veesler D, Pan J, Harrison SC, Potter CS, Carragher B, Grigorieff N. "Movies of ice-embedded particles enhance resolution in electron cryo-microscopy." Structure. 2012; 20(11):1823–1828.
Map: EMD-9127
Stoddard CI, Feng S, Campbell MG, Liu W, Wang H, Zhong X, Bernatavichute Y, Cheng Y, Jacobsen SE, Narlikar GJ. "A plant maintenance DNA methyltransferase is activated by the combinatorial action of chromatin architecture, histone methylation and DNA methylation." Mol Cell. 2019; 73(1):73-83.e6.
Maps: EMD-2718 to EMD-2749
Campbell MG, Smith BC, Potter CS, Carragher B, Marletta MA. "Molecular architecture of mammalian nitric oxide synthases." Proc Natl Acad Sci U S A. 2014;111(35):E3614–23
Maps: EMD-5861 to EMD-5878
Campbell MG, Underbakke ES, Potter CS, Carragher B, Marletta MA. "Single-particle EM reveals the higher-order domain architecture of soluble guanylate cyclase." Proc Natl Acad Sci U S A. 2014; 111(8):2960–2965.
Maps: EMD-5879 to EMD-5880
Campbell MG, Underbakke ES, Potter CS, Carragher B, Marletta MA. "Single-particle EM reveals the higher-order domain architecture of soluble guanylate cyclase." Proc Natl Acad Sci U S A. 2014; 111(8):2960–2965.
Maps: EMD-5881 to EMD-5884
Campbell MG, Underbakke ES, Potter CS, Carragher B, Marletta MA. "Single-particle EM reveals the higher-order domain architecture of soluble guanylate cyclase." Proc Natl Acad Sci U S A. 2014; 111(8):2960–2965.