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Nguyen A, Heim JB, Cordara G, Chan MC, Johannesen H, Charlesworth C, Li M, Azumaya CM, Madden B, Krengel U, Meves A, Campbell MG "Structural and functional characterization of integrin α5-targeting antibodies for anti-angiogenic therapy" 2025 Jan 08 https://www.biorxiv.org/content/10.1101/2025.01.08.631572v1
Jin MJ, Seed RI, Cai G, Shing T, Wang L, Ito S, Cormier A, Wankowicz SA, Jespersen JM, Baron JL, Carey ND, Campbell MG, Yu Z, Tang PK, Cossio P, Wen W, Lou J, Marks J, Nishimura SL, Cheng Y. "Dynamic allostery drives autocrine and paracrine TGF-β signaling" Cell. 2024 September 16. doi: https://doi.org/10.1016/j.cell.2024.08.036
Wang X, Guillem-Marti J, Kumar S, Lee DS, Cabrerizo-Aguado D, Werther R, Estrado Alamo KA, Zhao YT, Nguyen A, Kopyeva I, Huang B, Li J, Hao Y, Li X, Brizuela-Velasco A, Murray AN, Gerben S, Roy A, DeForest CA, Springer TA, Ruohola-Baker H, Cooper JA, Campbell MG, Manero JM, Ginebra MP, Baker D. "De Novo Design of Integrin α5β1 Modulating Proteins for Regenerative Medicine" bioRxiv. 2024 June 25. doi: https://doi.org/10.1101/2024.06.21.600123
Hollis JA, Chan MC, Malik HS, Campbell MG. "Evolutionary origin and structural ligand mimicry by the inserted domain of alpha-integrin proteins" bioRxiv. 2023 November 05. doi: https://doi.org/10.1101/2023.11.05.565221
Roy A*, Shi L*, Chang A*, Dong X, Fernandez A, Kraft JC, Li J, Le VQ, Winegar RV, Cherf GM, Slocum D, Poulson PD, Casper GE, Vallecillo-Zuniga ML, Valdoz JC, Miranda MC, Bai H, Kipnis Y, Olshefsky A, Priya T, Carter L, Ravichandran T, Chow C, Johnson MR, Chang A, Overed-Sayer C, Finch DK, Lowe D, Bera AK, Matute-Bello G, Birkland TP, DiMaio F, Raghu G, Cochran JR, Stewart L, Campbell MG#, Van Ry PM#, Springer TA#, Baker D#. "De novo design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8" Nat Commun. 2023 Sep 13;14(1):5660. doi: 10.1038/s41467-023-41272-z. PMID: 37704610
• bioRxiv. 2023 June 12; doi: https://doi.org/10.1101/2023.06.12.544624
Gupta M*, Azumaya CM*, Moritz M*, Pourmal S*, Diallo A*, Merz GE*, Jang G*, Bouhaddou M*, Fossati A*, Brilot AF, Diwanji D, Evelyn Hernandez E, Herrera N, Kratochvi HT, Lam VL, Li F, Yang Li Y, Nguyen HC, Nowotny C, Owens TW, Peters JK, Rizo AN, Schulze-Gahmen U, Smith AM, Young ID, Yu Z, Asarnow D, Billesbølle C, Campbell MG, Chen J, Chen K, Chio U, Dickinson MS, Doan L, Jin M, Kim K, Li J, Li Y, Linossi E, Liu Y, Lo M, Lopez J, Lopez KE, Mancino A, Moss III FR, Paul MD, Pawar KI, Pelin A, Pospiech Jr.TH, Puchades C, Remesh SG, Safari M, Schaefer K, Sun M, Tabios MC, Thwin AC, Titus EW, Trenker R, Tse E, Tsui TKM, Wang F, Zhang K, Zhang Y, Zhao J, Zhou F, Zhou Y, Zuliani-Alvarez L, QCRG Structural Biology Consortium, Agard DA, Cheng Y, Fraser JS, Jura N, Kortemme T, Manglik A, Southworth DR, Stroud RM, Swaney DL, Krogan NJ, Frost A, Rosenberg OS, Verba KA. "CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes." bioRxiv. 2021 May 12; 443524v1.
Campbell MG, Cormier A, Ito S, Seed RI, Bondesson AJ, Lou J, Marks JD, Baron JL, Cheng Y, Nishimura SL. "Cryo-EM reveals a mechanism of integrin-mediated TGF-β activation within the latent TGF-β complex" Cell. 2020 Feb 6;180(3):490-501.e16.
Palovcak E, Asarnow D, Campbell MG, Yu Z, Cheng Y. "Enhancing the signal-to-noise ratio and generating contrast for cryo-EM images with convolutional neural networks" IUCrJ. 2020 Oct 24;7(Pt 6):1142-1150.
Gordon DE, Hiatt J, Bouhaddou M, Rezelj VV, Ulferts S, Braberg H, Jureka AS, Obernier K, Guo JZ, Batra J, Kaake RM, Weckstein AR, Owens TW, Gupta M, Pourmal S, Titus EW, Cakir M, Soucheray M, McGregor M, Cakir Z, Jang G, O'Meara MJ, Tummino TA, Zhang Z, Foussard H, Rojc A, Zhou Y, Kuchenov D, Hüttenhain R, Xu J, Eckhardt M, Swaney DL, Fabius JM, Ummadi M, Tutuncuoglu B, Rathore U, Modak M, Haas P, Haas KM, Naing ZZC, Pulido EH, Shi Y, Barrio-Hernandez I, Memon D, Petsalaki E, Dunham A, Marrero MC, Burke D, Koh C, Vallet T, Silvas JA, Azumaya CM, Billesbølle C, Brilot AF, Campbell MG, Diallo A, Dickinson MS, Diwanji D, Herrera N, Hoppe N, Kratochvil HT, Liu Y, Merz GE, Moritz M, Nguyen HC, Nowotny C, Puchades C, Rizo AN, Schulze-Gahmen U, Smith AM, Sun M, Young ID, Zhao J, Asarnow D, Biel J, Bowen A, Braxton JR, Chen J, Chio CM, Chio US, Deshpande I, Doan L, Faust B, Flores S, Jin M, Kim K, Lam VL, Li F, Li J, Li YL, Li Y, Liu X, Lo M, Lopez KE, Melo AA, Moss FR 3rd, Nguyen P, Paulino J, Pawar KI, Peters JK, Pospiech TH Jr, Safari M, Sangwan S, Schaefer K, Thomas PV, Thwin AC, Trenker R, Tse E, Tsui TKM, Wang F, Whitis N, Yu Z, Zhang K, Zhang Y, Zhou F, Saltzberg D; QCRG Structural Biology Consortium, Hodder AJ, Shun-Shion AS, Williams DM, White KM, Rosales R, Kehrer T, Miorin L, Moreno E, Patel AH, Rihn S, Khalid MM, Vallejo-Gracia A, Fozouni P, Simoneau CR, Roth TL, Wu D, Karim MA, Ghoussaini M, Dunham I, Berardi F, Weigang S, Chazal M, Park J, Logue J, McGrath M, Weston S, Haupt R, Hastie CJ, Elliott M, Brown F, Burness KA, Reid E, Dorward M, Johnson C, Wilkinson SG, Geyer A, Giesel DM, Baillie C, Raggett S, Leech H, Toth R, Goodman N, Keough KC, Lind AL; Zoonomia Consortium, Klesh RJ, Hemphill KR, Carlson-Stevermer J, Oki J, Holden K, Maures T, Pollard KS, Sali A, Agard DA, Cheng Y, Fraser JS, Frost A, Jura N, Kortemme T, Manglik A, Southworth DR, Stroud RM, Alessi DR, Davies P, Frieman MB, Ideker T, Abate C, Jouvenet N, Kochs G, Shoichet B, Ott M, Palmarini M, Shokat KM, García-Sastre A, Rassen JA, Grosse R, Rosenberg OS, Verba KA, Basler CF, Vignuzzi M, Peden AA, Beltrao P, Krogan NJ. "Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms" Science. 2020 Oct 15:eabe9403. doi: 10.1126/science.abe9403.
Wang F, Yu Z, Betegon M, Campbell MG, Aksel T, Zhao J, Li S, Cheng Y, Agard DA. "Amino and PEG-Amino Graphene Oxide Grids Enrich and Protect Samples for High-resolution Single Particle Cryo-electron Microscopy." J Struct Biol. 2020 Feb 1;209(2):107437.
• bioRxiv; 2019 October 22; doi: https://doi.org/10.1101/813972
Rosen L, Klebba J, Asfaha J, Ghent C, Campbell MG, Cheng Y, Morgan DO. "Cohesin cleavage by separase is enhanced by a substrate motif distinct from the cleavage site." Nat Commun. 2019; 10, 5189.
Stoddard CI, Feng S, Campbell MG, Liu W, Wang H, Zhong X, Bernatavichute Y, Cheng Y, Jacobsen SE, Narlikar GJ. "A plant maintenance DNA methyltransferase is activated by the combinatorial action of chromatin architecture, histone methylation and DNA methylation." Mol Cell. 2019; 73(1):73-83.e6.
Takasaka N, Seed RI, Cormier A, Bondesson AJ, Lou J, Elattma A, Ito S, Yanagisawa H, Hashimoto M, Ma R, Levine MD, Publicover J, Potts R, Jespersen JM, Campbell MG, Conrad F, Marks J, Cheng Y, Baron JL, Nishimura SL. "Integrin avb8 expressing tumor cells evade host immunity by regulating TGF-b activation in immune cells." JCI Insight. 2018; 3(20):e122591.
Cormier A, Campbell MG, Ito S, Wu S, Lou J, Marks J, Baron J, Nishimura SL, Cheng Y. "Cryo-EM structure of the αvβ8 integrin reveals a mechanism for stabilizing integrin extension." Nat Struct Mol Biol. 2018; 25(8):698–704.
Autzen HE, Myasnikov AG, Campbell MG, Asarnow D, Julius D, Cheng Y. "Structure of the human TRPM4 ion channel in a lipid nanodisc." Science. 2018; 359 (6372), 228-232.
Binning JM, Smith AM, Hultquist JF, Craik CS, Caretta N, Campbell MG, Burton L, La Greca F, McGregor MJ, Ta HM, Bartholomeeusen K, Peterlin BM, Krogan NJ, Sevillano N, Cheng Y, Gross JD. "Fab-based inhibitors reveal ubiquitin independent functions for HIV Vif neutralization of APOBEC3 restriction factors." PLOS Pathogens. 2018; 14(1):e1006830.
Yu X, Veesler D, Campbell MG, Barry ME, Asturias FJ, Barry MA and Reddy VS. "Cryo-EM structure of human adenovirus D26 reveals the conservation of structural organization among human adenoviruses." Science Advances. 2017; 3(5):e1602670.
Campbell MG, Veesler D, Cheng A, Potter CS, Carragher B. "2.8 Å resolution reconstruction of the Thermoplasma acidophilum 20S proteasome using cryo-electron microscopy." eLife. 2015; 4:e06380.
Campbell MG, Kearney BM, Cheng A, Potter CS, Johnson JE, Carragher B, Veesler D. "Near-atomic resolution reconstructions using a mid-range electron microscope operated at 200kV." J Struct Biol. 2014; 188(2):183-187.
Campbell MG, Smith BC, Potter CS, Carragher B, Marletta MA. "Molecular architecture of mammalian nitric oxide synthases." Proc Natl Acad Sci U S A. 2014;111(35):E3614–23.
Campbell MG, Underbakke ES, Potter CS, Carragher B, Marletta MA. "Single-particle EM reveals the higher-order domain architecture of soluble guanylate cyclase." Proc Natl Acad Sci U S A. 2014; 111(8):2960–2965.
Veesler D, Campbell MG, Cheng A, Fu C-Y, Murez Z, Johnson JE, Potter CS, Carragher B. Maximizing the potential of electron cryomicroscopy data collected using direct detectors. J Struct Biol. 2013; 184(2):193–202.
Campbell MG, Cheng A, Brilot AF, Moeller A, Lyumkis D, Veesler D, Pan J, Harrison SC, Potter CS, Carragher B, Grigorieff N. Movies of ice-embedded particles enhance resolution in electron cryo-microscopy. Structure. 2012; 20(11):1823–1828.
Fiedler JD, Higginson C, Hovlid ML, Kislukhin AA, Castillejos A, Manzenrieder F, Campbell MG, Voss NR, Potter CS, Carragher B, Finn MG. "Engineered mutations change the structure and stability of a virus-like particle." Biomacromolecules. 2012; 13(8):2339–2348.
Campbell MG, Karbstein K. "Protein-protein interactions within late pre-40S ribosomes." PloS one. 2011; 6(1):e16194.
Ma J, Peng L, Zhang X, Zhang Z, Campbell M, Wang J. "InI- or ZnI-catalyzed reaction of hydroxylated 1,5-allenynes with thiols: a new access to 3,5-disubstituted toluene derivatives." Chemistry, an Asian journal. 2010; 5(10):2214–2220.
Grzyska PK, Muller TA, Campbell MG, Hausinger RP. "Metal ligand substitution and evidence for quinone formation in taurine/alpha-ketoglutarate dioxygenase." Journal of inorganic biochemistry. 2007; 101(5):797–808.