Journal Club

Crystals of a computationally designed protein
Crystals of a computationally designed protein Image by Lindsey Doyle

2023-2024 FHCRC Structural Biology and Molecular Biophysics Journal Club

Fred Hutch's Structural Biology and Molecular Biophysics Journal Club is held from 11:00 am - 12:00 pm on Thursdays in A3M-015.

Date Presenter Topic / Manuscript
October 12 Chris LaPointe Dynamics & disruption of human translation initiation
November 2 Barry Stoddard


Enustun et al. (2023) "A phage nucleus-associated RNA-binding protein is required for jumbo phage infection" (BioRxiv Posting)   

November 16 Nick Hurlbert (Pancera Group)


Structure-based design of a chimeric antigen for a malaria vaccine

Patel et al. (2023) "Structure-based design of a strain trnascending AMA1-RON2L malaria vaccine" Nature Communications 14: 5345.

Yanik et al. (2023) "Structure guided mimicry of an essential P. falciparum receptor-ligand complex enhances cross neutralizing antibodies" Nature Communications 14: 5879.

December 7 Jeremy Hollis (Campbell Group)


X-ray free electron lasers (XFEL) and studies of rhodopsin photoactivation

Gruhl et al. (2023) "Ultrafast structural changes direct the first molecular events of vision" Nature 615: 939 - 944.

(and a background review if you wish)

Branden and Neutze (2021) "Advances and challenges in time-resolved macromolecular crystallography" Science 373 (80): doi: 10.1126/science.aba0954.

January 11 Peter Rupert (Strong Group)


Beenken et al. (2023) "Structures of LRP2 reveal a molecular machine for endocytosis" Cell 186 (4): 821 - 836.

January 25 Adam Nguyen (Campbell Group)  
February 15 Gargi Kher (Pancera Group)  
March 7 Andrew Fernandez (Campbell Group)


April 4 Yasuhiro Arimura  
April 25 Juliana Young (Stoddard Group)  
May 16 Morgan McGovern (Pancera Group)  
June 6 Matthew Chan (Campbell Group)  
June 27 Thamiya Vasanthakumar (Campbell Group)