Journal Club

Crystals of a computationally designed protein
Crystals of a computationally designed protein Image by Lindsey Doyle

2024-2025 Fred Hutch Structural Biology and Molecular Biophysics Journal Club

Fred Hutch's Structural Biology and Molecular Biophysics Journal Club is held 10:30 am - 11:30 am on Thursdays in B1-072/074 unless otherwise noted on the dates below.

DatePresenterTopic / Manuscript
October 2Roland Strong“You should know what we did last summer”
October 9 - O’Mack Symposium Suite (S1-141/142)CryoEM Symposium
 
October 23Adam Nguyen (Campbell Lab)

"Plexins. Their dimeric structure using cryoEM and activation modulation by de novo FC peptide ligands."

Kuo YC, Chen H, Shang G, Uchikawa E, Tian H, Bai XC, Zhang X. Cryo-EM structure of the PlexinC1/A39R complex reveals inter-domain interactions critical for ligand-induced activation. Nat Commun. 2020 Apr 23;11(1):1953. doi: 10.1038/s41467-020-15862-0. PMID: 32327662; PMCID: PMC7181871.

Sugano-Nakamura N, Matoba K, Hirose M, Bashiruddin NK, Matsunaga Y, Yamashita K, Hirata K, Yamamoto M, Arimori T, Suga H, Takagi J. De novo Fc-based receptor dimerizers differentially modulate PlexinB1 function. Structure. 2022 Oct 6;30(10):1411-1423.e4. doi: 10.1016/j.str.2022.07.008. Epub 2022 Aug 17. PMID: 35981535.

November 13Peter Rupert (Strong Lab)

 

December 4Matthew Chan (Campbell Lab) 

 

December 18Sydney McGuire (Lapointe Lab) 
January 8
Alex Kaiser (Stoddard Lab)

 

 

January 29Jeremy Hollis (Campbell Lab)

 

 

February 19Rachel Cueny (Lapointe Lab)

 

 

March 12Thamiya Vasanthakumar (Campbell Group) 
April 23Nick Hurlburt (Pancera Lab) 
May 14Andrés Fernández (Campbell/Subramaniam Lab)

 

 

June 4Morgan Esler (Stoddard Lab)

 

 

June 25Eva Alleman (Campbell Lab)