"cryoEM Structures of tyrosine kinase receptors"

Reading: Huang et al. and Kuriyan, J. (2021) "A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor" eLife  (https://doi.org/10.7554/eLife.73218)

“Ferritin-scFv: A potential method for mapping of epitopes”

Reading: Knovich et al. (2009) "Ferritin for the Clinician" Blood Reviews 23: 95 -104. https://www.sciencedirect.com/science/article/pii/S0268960X08000660

“The mobilization, divergence, degradation, and reconstruction of modern-day and ancestral homing endonucleases”

"Computational design of prefusion-stabilized Herpesvirus gB trimers”

Reading:   https://pmc.ncbi.nlm.nih.gov/articles/PMC11526958/

"Look, up in the lysosome! It's a transporter! It’s a GPCR! It’s…LYCHOS!"

Reading: https://www.nature.com/articles/s41594-024-01474-5

"Improving Anti-Venom (Never tell me the odds)"

Reading: Vázquez Torres, S., Benard Valle, M., Mackessy, S.P. et al. De novo designed proteins neutralize lethal snake venom toxins. Nature (2025). DOI

"Structural biology of Factor VIII complexes: characterizing inhbitor epitopes in haemophila A treatment"

(Or: "Grad school: you can check out, but you can never leave")

"cryoET as a structural window into the cell."

Reading: 

Rodrigues-Oliveira, T., Wollweber, F., Ponce-Toledo, R.I. et al. Actin cytoskeleton and complex cell architecture in an Asgard archaeon. Nature 613, 332–339 (2023). DOI

Young LN, Villa E. Bringing Structure to Cell Biology with Cryo-Electron Tomography. Annu Rev Biophys. 2023 May 9;52:573-595. doi: 10.1146/annurev-biophys-111622-091327. PMID: 37159298; PMCID: PMC10763975.

Nogales E, Mahamid J. Bridging structural and cell biology with cryo-electron microscopy. Nature. 2024 Apr;628(8006):47-56. doi: 10.1038/s41586-024-07198-2. Epub 2024 Apr 3. PMID: 38570716; PMCID: PMC11211576.

"Deconvoluting disparate roles of DDX6 in translational control"

Reading:

Coller J, Parker R. General translational repression by activators of mRNA decapping. Cell. 2005 Sep 23;122(6):875-86. doi: 10.1016/j.cell.2005.07.012. PMID: 16179257; PMCID: PMC1853273.

"Cryo-electron tomography reveals how COPII assembles on cargo-containing membranes”

Reading:

Pyle, E., Miller, E.A. & Zanetti, G. Cryo-electron tomography reveals how COPII assembles on cargo-containing membranes. Nat Struct Mol Biol 32, 513–519 (2025). DOI

"Gating mechanism of the two-pore-domain potassium channel THIK1”

Reading:

Fang X, Jin H, Wang J, Zhang R, Li B. Gating mechanism of the two-pore-domain potassium channel THIK1. Nat Struct Mol Biol. 2025 Apr 30. doi: 10.1038/s41594-025-01542-4. Epub ahead of print. PMID: 40307591.       https://www.nature.com/articles/s41594-025-01542-4

"Understanding the structural basis of metal ion transport by human NRAMP proteins"

Reading:

Liziczai, M., Fuchs, A., Manatschal, C. et al. Structural basis for metal ion transport by the human SLC11 proteins DMT1 and NRAMP1. Nat Commun 16, 761 (2025). DOI

"From Viral Proteins to DNA Complexes: Structural Insights, Diagnostic Tools, and Design Challenges”

Reading:

Basu et al. (2025) “Twenty years of advances in prediction of nucleic acid binding residues in protein sequences” Briefings in Bioinformatics 26 (1). DOI