Publications

Visit Pub Med to view Dr. Peterson’s complete publication record.

2026 | 2025 2024 | 2023

2026

Smac mimetic combined with eCD4-Ig reverses latency without reducing SHIV reservoirs in rhesus macaques

Pache L, Bui JK, Klouser LM, Fennessey CM, Noyola AC, Einhaus T, Zhu H, Stensland L, Leguizamo I, Koroma AA, Teriete P, Chang WLW, Hyrien O, Duggan NN, Heimann D, Pérez-Osorio AC, Bar KJ, Cosford ND, Keele BF, Hartigan-O'Connor DJ, Farzan M, Gardner MR, Jerome KR, Chanda SK, Kiem HP, Peterson CW. Smac mimetic combined with eCD4-Ig reverses latency without reducing SHIV reservoirs in rhesus macaques. J Clin Invest. 2026 Mar 16;136(6):e187961. doi: 10.1172/JCI187961. PMID: 41837286; PMCID: PMC12987619

Antigen-boosted CD4 CAR-T cells fail to expand or control viremia in multiple nonhuman primate models of HIV

Maynard L, Starke CE, Poole NH, Rust BJ, Zhu H, Stensland L, Huang ML, Pérez-Osorio AC, Atherley JI, Einhaus TK, Murray JD, Pampena MB, Betts MR, Jerome KR, Riley JL, Kiem HP, Peterson CW. Antigen-boosted CD4 CAR-T cells fail to expand or control viremia in multiple nonhuman primate models of HIV. Blood. 2026 Feb 24:blood.2025032142. doi: 10.1182/blood.2025032142. Epub ahead of print. PMID: 41734346

Engraftment of gene-edited hematopoietic stem cells after antibody-drug conjugate conditioning in nonhuman primates

Murray J, Einhaus T, Radtke S, Bar KJ, Peterson CW, Kiem HP. Engraftment of gene-edited hematopoietic stem cells after antibody-drug conjugate conditioning in nonhuman primates. Blood Adv. 2026 Feb 24;10(4):1094-1105. doi: 10.1182/bloodadvances.2025017838. PMID: 41324589; PMCID: PMC12915210


2025

Pooled CAR-T screening in nonhuman primates identifies designs with enhanced proliferation, trafficking, and persistence

Lucy H. Maynard, Eric J. Cavanaugh, Haiying Zhu, Carly E. Starke, Sarah M. Doherty, Teresa Einhaus, Ailyn Perez, Laurence Stensland, Michelle Hoffman, Veronica Nelson, Sarah Herrin, Chad Littlewood, Kaycee Camou, Erica Wilson, Christopher Wessel, Keith R. Jerome, Hans-Peter Kiem, Christopher W. Peterson
 

Heavy-chain immunoglobulin locus editing in rhesus macaque B cells to confer antibody production

Kuhlmann AS, Madkhali N, Moskovitz E, Parrott JE, Raman SS, Riker AO, Martinez-Reyes J, Gupta M, Jang RA, Nelson V, Gray MD, Taylor JJ, Peterson CW, Kiem HP. Heavy-chain immunoglobulin locus editing in rhesus macaque B cells to confer antibody production. Mol Ther Methods Clin Dev. 2025 Sep 22;33(4):101598. doi: 10.1016/j.omtm.2025.101598. PMID: 41146877; PMCID: PMC12554106


2024

Anti-PD-1 chimeric antigen receptor T cells efficiently target SIV-infected CD4+ T cells in germinal centers.

Eichholz K, Fukazawa Y, Peterson CW, Haeseleer F, Medina M, Hoffmeister S, Duell DM, Varco-Merth BD, Dross S, Park H, Labriola CS, Axthelm MK, Murnane RD, Smedley JV, Jin L, Gong J, Rust BJ, Fuller DH, Kiem HP, Picker LJ, Okoye AA, Corey L.J Clin Invest. 2024 Apr 1;134(7):e169309. doi: 10.1172/JCI169309.PMID: 38557496 

CD20 CAR T cells safely and reversibly ablate B cell follicles in a non-human primate model of HIV persistence.

Bui JK, Starke CE, Poole NH, Rust BJ, Jerome KR, Kiem HP, Peterson CW.Mol Ther. 2024 May 1;32(5):1238-1251. doi: 10.1016/j.ymthe.2024.02.030. Epub 2024 Feb 27.PMID: 38414244

Stem cell-derived CAR T cells show greater persistence, trafficking, and viral control compared to ex vivo transduced CAR T cells.

Carrillo MA, Zhen A, Mu W, Rezek V, Martin H, Peterson CW, Kiem HP, Kitchen SG.Mol Ther. 2024 Apr 3;32(4):1000-1015. doi: 10.1016/j.ymthe.2024.02.026. Epub 2024 Feb 27.PMID: 38414243 


2023

Efficient manufacturing and engraftment of CCR5 gene-edited HSPCs following busulfan conditioning in nonhuman primates.

Murray J, Einhaus T, Venkataraman R, Radtke S, Zhen A, Carrillo MA, Kitchen SG, Peterson CW, Kiem HP.Mol Ther Methods Clin Dev. 2023 Jul 18;30:276-287. doi: 10.1016/j.omtm.2023.07.006. eCollection 2023 Sep 14.PMID: 37575091

Efficient ex vivo expansion of conserved element vaccine-specific CD8+ T-cells from SHIV-infected, ART-suppressed nonhuman primates.

Dross S, Venkataraman R, Patel S, Huang ML, Bollard CM, Rosati M, Pavlakis GN, Felber BK, Bar KJ, Shaw GM, Jerome KR, Mullins JI, Kiem HP, Fuller DH, Peterson CW.Front Immunol. 2023 May 3;14:1188018. doi: 10.3389/fimmu.2023.1188018. eCollection 2023.PMID: 37207227

A multiplexed barcode approach to simultaneously evaluate gene delivery by adeno-associated virus capsid variants in nonhuman primates.

Stone D, Meumann N, Kuhlmann AS, Peterson CW, Xie H, Roychoudhury P, Loprieno MA, Vu XK, Strongin DE, Kenkel EJ, Haick A, Stensland L, Obenza WM, Parrott J, Nelson V, Murnane RD, Huang ML, Aubert M, Kiem HP, Büning H, Jerome KR.Hepatol Commun. 2023 Jan 20;7(2):e0009. doi: 10.1097/HC9.0000000000000009. eCollection 2023 Feb 1.PMID: 37074875 

Stable HIV decoy receptor expression after in vivo HSC transduction in mice and NHPs: Safety and efficacy in protection from SHIV.

Li C, Anderson AK, Wang H, Gil S, Kim J, Huang L, Germond A, Baldessari A, Nelson V, Bar KJ, Peterson CW, Bui J, Kiem HP, Lieber A.Mol Ther. 2023 Apr 5;31(4):1188. doi: 10.1016/j.ymthe.2023.02.019. Epub 2023 Mar 6.PMID: 36882062 

Stable HIV decoy receptor expression after in vivo HSC transduction in mice and NHPs: Safety and efficacy in protection from SHIV.

Li C, Anderson AK, Wang H, Gil S, Kim J, Huang L, Germond A, Baldessari A, Nelson V, Bar KJ, Peterson CW, Bui J, Kiem HP, Lieber A.Mol Ther. 2023 Apr 5;31(4):1059-1073. doi: 10.1016/j.ymthe.2023.02.002. Epub 2023 Feb 9.PMID: 36760126 


Dr. Peterson’s complete publication record.

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